A5077388431- Global Cancer Incidence and Screening
- Colorectal Cancer Treatments and Studies
- Lung Cancer Treatments and Mutations
- Breast Cancer Treatment Studies
- Head and Neck Cancer Studies
- Vitamin C and Antioxidants Research
- Esophageal and GI Pathology
- Lung Cancer Diagnosis and Treatment
- Nutrition and Health in Aging
- Neuroendocrine Tumor Research Advances
- Cancer Diagnosis and Treatment
- Cancer Immunotherapy and Biomarkers
- Childhood Cancer Survivors' Quality of Life
- Lung Cancer Research Studies
- Pancreatic and Hepatic Oncology Research
- Advances in Oncology and Radiotherapy
- Neuroblastoma Research and Treatments
- Multiple and Secondary Primary Cancers
- Esophageal Cancer Research and Treatment
- Stoma care and complications
- Economic and Financial Impacts of Cancer
- Colorectal Cancer Surgical Treatments
- Cancer survivorship and care
- Vitamin D Research Studies
- Health Literacy and Information Accessibility
University of Iowa Hospitals and Clinics
2022-2025
University of Iowa
2022-2024
Moffitt Cancer Center
2019-2024
University of South Florida
2024
University of Miami
2006-2021
Tufts Medical Center
2018-2021
Sylvester Comprehensive Cancer Center
2009-2021
King Fahad Specialist Hospital
2021
Tufts University
2018-2019
Northwell Health
2019
Aliment Pharmacol Ther 28 , 312–325 Summary Background Post‐operative ileus (POI) affects most patients undergoing abdominal surgery. Aim To evaluate the effect of alvimopan, a peripherally acting mu‐opioid receptor antagonist, on POI by negating impact opioids gastrointestinal (GI) motility without affecting analgesia in outside North America. Methods Adult subjects open surgery ( n = 911) randomly received oral alvimopan 6 or 12 mg, placebo, 2 h before, and twice daily following Opioids...
In Brief Objective: To compare outcomes for patients with hepatocellular carcinoma (HCC) treated either liver resection or transplantation. Methods: A retrospective, single-institution analysis of 413 HCC from 1999 to 2009. Results: total underwent surgical (n = 106) and transplantation 270) were listed without receiving 37). Excluding transplanted incidental tumors 50), 257 suspected the intent transplant (ITT). The median diameter largest tumor by radiography was 6.0 cm in resected, 3.0...
Platinum-based chemotherapy with or without immunotherapy is the mainstay of treatment for advanced stage non-small cell lung cancer (NSCLC) lacking a molecular driver alteration. Pre-clinical studies have reported that pharmacological ascorbate (P-AscH-) enhances NSCLC response to platinum-based therapy. We conducted phase II clinical trial combining P-AscH- carboplatin-paclitaxel chemotherapy.Chemotherapy naïve patients received 75 g twice per week intravenously carboplatin and paclitaxel...
Immune-checkpoint inhibitors (ICIs) have revolutionized lung cancer (LC) treatment; however, immune-related adverse effects (irAEs) may occur. The risk factors of irAEs and the impact on patient outcomes in LC remain uncertain. within 12 months ICI initiation patients who initiated ICIs 2018-2021 were identified. Cause-specific Cox regression was used to assess for with competing death; a subset analysis done among non-small cell (NSCLC) group. Multivariable regressions evaluate...
Malnutrition is a common and distressing condition among pancreatic cancer patients. Fewer than quarter of patients receive medical nutrition therapy (MNT), important for improving nutritional status, weight maintenance, quality life survival. System, provider, patient level barriers limit access to MNT. We propose examine the feasibility 12-week multi-level, digital health intervention designed expand MNT Individuals with advanced starting chemotherapy (N = 80) will be 1:1 randomized or...
We describe the characteristics of individuals being screened in community settings including factors influencing screening decisions and level information sought prior to screening. Individuals from two community-based radiology clinics (N = 27) were surveyed after Screening efficacy salience most important decisions, whereas healthcare provider recommendations rated not important. Half participants reported no or little conversation about with their primary care provider, 61.5 percent had...
With the increased use of immune checkpoint inhibitors (ICI), it is essential to improve our understanding immune-related adverse events (irAE). To date, most studies describing irAE have been performed in clinical trial populations, which may not be an accurate description real-world populations. Also, identification patients at risk needed as early recognition outcomes.
Private information induces individuals to self-select as subjects into clinical research trials, and it researchers select which trials they conduct. The authors show that selection can induce ex ante therapeutic misconception post disappointment among subjects, undermines the rationale of collective equipoise an ethical basis for trials. Selection provides a reason make nontrivial payments implies should not design experiments maximize statistical power.
We sought to determine whether patients with esophageal carcinoma benefit from regionalization of care.The Florida Cancer Data System (FCDS) and the Agency for Health Care Administration data sets (1998-2002) were merged queried.A total 5,041 (87.6% Caucasian vs. 11.1% African American (AA)) demonstrated a median survival time 9.8 months overall 23.4 following surgical resection (P < 0.001). Adenocarcinoma arose predominantly in (98.1%). Patients adenocarcinoma (n = 2,248) derived treatment...
Caregivers are engaging in recreational travel with the neuro-oncology patients they care for, yet there is little scientific research on this phenomenon.
Background Patients with small cell lung cancer (SCLC) often respond to first-line chemoimmunotherapy. However, relapse is inevitable and associated a poor prognosis. Treatments for relapsed SCLC, such as lurbinectedin topotecan, are limited by modest efficacy significant hematologic adverse events, leaving need newer therapeutic agents or regimens. The combination of gemcitabine nab-paclitaxel active safe in other types malignancies, pancreatic cancer. methods We conducted phase II trial...
e14561 Background: TYMS catalyzes methylation of dUMP to dTMP. As the sole de novo source thymidylate in cell it is an important target for 5-FU/CAP. Overexpression has been linked resistance these agents both vitro and vivo. Cause variability expression unclear, however, polymorphisms 5 3 untranslated regions (5UTR 3UTR) gene have described previously are suggested impact on efficacy TYMS-targeted chemotherapy. We analyzed genotyping its role with outcome pts treated Methods: was assessed...
1. Substantial contributions to conception and design.2. Acquisition of data analysis.3. Interpretation data.4. Drafting the article or revising it critically for important intellectual content. 5.
Welcome to Annals of Global Health,Annals Health is a peer-reviewed, fully open access, online journal dedicated publishing high quality articles all aspects global health. The journal's mission advance health, promote research, and foster the prevention treatment disease worldwide. Its goals are improve health well-being people, equity, wise stewardship earth's environment. latest impact factor 3.64.Annals supported by Program for Public Common Good at Boston College. It was founded in 1934...