- Coronary Interventions and Diagnostics
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Orthopaedic implants and arthroplasty
- Cardiac and Coronary Surgery Techniques
- Ultrasound and Hyperthermia Applications
- Cardiovascular Disease and Adiposity
- Titanium Alloys Microstructure and Properties
- Lipoproteins and Cardiovascular Health
- Cardiovascular Effects of Exercise
- Cardiac, Anesthesia and Surgical Outcomes
- Hernia repair and management
- Global Health and Surgery
- Aluminum Alloys Composites Properties
- Integrated Circuits and Semiconductor Failure Analysis
- Sex and Gender in Healthcare
- Peripheral Artery Disease Management
- Innovations in Medical Education
- Spine and Intervertebral Disc Pathology
- Aortic aneurysm repair treatments
Odense University Hospital
2016-2025
University of Southern Denmark
2024-2025
Al Yarmouk University College
2018
BACKGROUND: Bioresorbable scaffolds (BRS) were developed to overcome limitations related late stent failures of drug-eluting stents, but lumen reductions over time after implantation BRS have been reported. This study aimed investigate if lesion preparation with a scoring balloon compared standard noncompliant minimizes reduction Magmaris assessed optical coherence tomography and intravascular ultrasound. METHODS: Eighty-two patients stable angina randomized in ratio 1:1 versus before BRS....
Myocardial dysfunction and the presence of calcified non-calcified coronary plaques are predictors cardiovascular disease. Masculinizing gender-affirming hormone therapy may increase risk, highlighting need for prospective studies to evaluate outcomes during therapy. To changes in cardiac morphology, systolic diastolic function, development after masculinizing Prospective study including 47 transmasculine persons (gender-affirming therapy-naïve, TransM_TN, n = 15 therapy-ongoing, TransM_TO,...
Percutaneous coronary intervention with implantation of a bioresorbable scaffold (BRS) provide the vessel support for limited period allowing to restore normal vasomotion after degradation BRS, opposed treatment drug-eluting stents where metal persist in wall. Late lumen loss and reduction area have been reported. The purpose this study was investigate whether intense pre-dilatation before BRS resulted less minimal at 6- 12-month follow-up Magmaris (MgBRS). Coronary imaging optical coherence...
Background: Biodegradable polymer drug-eluting stents were developed to improve safety and efficacy outcomes for patients undergoing percutaneous coronary intervention. However, few long-term follow-up studies are available. The study sought investigate 5-year results from the SORT OUT VII trial (Scandinavian Organization Randomized Trials With Clinical Outcome) comparing biodegradable ultrathin-strut sirolimus-eluting Orsiro stent (O-SES) versus biolimus-eluting Nobori (N-BES). Methods:...
Abstract Background Bioresorbable scaffolds (BRS) have been proposed as an alternative to drug-eluting stents (DES), offering radial support during the early phases of healing, while potentially reducing risk long-term complications. A magnesium-based BRS (MgBRS) has shown promising results after implantation. However, there is a lack knowledge regarding outcomes. Case summary 62-year-old man with hypertension, dyslipidaemia, family history ischaemic heart disease, and previous myocardial...
The purpose of a bioresorbable scaffold (BRS) is to provide radial support during coronary healing. In this study, artery healing after optical coherence tomography (OCT)- versus angiography-guided magnesium BRS (MBRS) implantation in patients with non-ST-segment-elevation myocardial infarction (NSTEMI) compared. 75 were randomized 1:1 OCT- or MBRS protocolled pre- and post-dilation. the OCT-guided group, prespecified criteria indicating additional intervention (1) under-expansion, (2) strut...
The relation between the resting full cycle ratio (RFR) and fractional flow reserve (FFR) is not fully understood. This study aims to investigate influence of coronary microvascular dysfunction, assessed by index resistance (IMR), on RFR compared FFR in patients undergoing functional assessment for stenosis. Two-hundred with borderline stenosis underwent RFR, FFR, (CFR) IMR. Retriever operator curve analysis was performed assess diagnostic value (IMR ≥ 24) < 24). Median did differ...
The purpose of the study was to investigate incidence, cause and probability re-hospitalization within 30 365 days after percutaneous coronary intervention (PCI) in patients with diabetes.Between January 2010 September 2014, 2763 diabetes were treated PCI at two Hospitals Western Denmark. Reasons for readmission identified.Readmission risks 58% 18% days. Reason ischemic heart disease (IHD) 725 (27%), non-IHD-related reasons 826 (31%). IHD-related associated female gender (OR 1.3, 95% CI:...
Abstract Introduction Bioresorbable scaffolds (BRS) have been developed to overcome limitations related late stent failures of drug-eluting-stents, but previous studies observed lumen reduction over time after implantation BRS. The aim the study was investigate if lesion preparation with a scoring balloon compared standard non-compliant minimizes Magmaris BRS (MgBRS) assessed optical coherence tomography (OCT) and intravascular ultrasound (IVUS). Method Eighty-two patients stable angina...
Diabetes mellitus is associated with higher risk of target lesion failure (TLF) after percutaneous coronary intervention. We studied the 5-year outcome in patients diabetes treated biodegradable polymer stents.
<b><i>Background:</i></b> Bioresorbable scaffolds (BRSs) is a relatively new approach in treating coronary artery stenosis. The initial results of the first commercially available consisting backbone poly-L-lactide raised safety concerns related to delayed resorption and healing. magnesium alloy-based scaffold degrades via bio-corrosion within months, whereas it often takes several years for polymer degrade. aim study was assess healing stage by optical coherence...
Introduction: Percutaneous coronary intervention with implantation of a bioresorbable scaffold (BRS) provide the vessel support for limited period allowing to restore normal vasomotion after degradation BRS, opposed treatment drug-eluting stents where metal persist in vesselwall. Late lumen loss and reduction area have been reported. The purpose this study is investigate whether intense pre-dilatation before BRS will result less minimal at 6- 12-month follow-up Magmaris (MgBRS). Coronary...
Abstract Background Patients with acute coronary syndromes (ACS) may have worse outcomes after percutaneous intervention compared to patients without ACS. Aims To compare 5‐year efficacy and safety in ACS treated biodegradable polymers, the ultrathin strut sirolimus‐eluting Orsiro stent (O‐SES) or biolimus‐eluting Nobori (N‐BES). Methods The Scandinavian Organisation for Randomized Trials Clinical Outcome VII is a randomized trial comparing O‐SES N‐BES an all‐comer setting. Of 2525 patients,...