A5002922014- Musculoskeletal pain and rehabilitation
- Anesthesia and Sedative Agents
- Anesthesia and Pain Management
- Pain Management and Treatment
- Airway Management and Intubation Techniques
- Spine and Intervertebral Disc Pathology
- Cardiac, Anesthesia and Surgical Outcomes
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Hemodynamic Monitoring and Therapy
- Myofascial pain diagnosis and treatment
- EEG and Brain-Computer Interfaces
- Blood transfusion and management
- Nausea and vomiting management
- Intensive Care Unit Cognitive Disorders
- Transcranial Magnetic Stimulation Studies
- Transplantation: Methods and Outcomes
- Intraoperative Neuromonitoring and Anesthetic Effects
- Pain Mechanisms and Treatments
- Cardiac Arrest and Resuscitation
- Anesthesia and Neurotoxicity Research
- Pediatric Pain Management Techniques
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Neurosurgical Procedures and Complications
- Adrenal Hormones and Disorders
- Pain Management and Opioid Use
Erasmus Hospital
2006-2025
Université Libre de Bruxelles
2008-2025
Université Paris-Saclay
2023
Outcomes Research Consortium
2023
Assistance Publique – Hôpitaux de Paris
2023
University Hospital of Lausanne
2017
Homeostatic turnover of the extracellular matrix conditions structure and function healthy lung. In lung transplantation, long-term management remains limited by chronic allograft dysfunction, an umbrella term used for a heterogeneous entity ultimately associated with pathological airway and/or parenchyma remodeling.This study assessed whether local cross-talk between pulmonary microbiota host cells is key determinant in control lower remodeling posttransplantation.Microbiota DNA total RNA...
Introduction Spinal cord stimulation is a common treatment option for neuropathic pain conditions. Despite its extensive use and multiple technological evolutions, long term efficacy of spinal debated. Most studies on include rather limited number patients and/or follow-ups over period. Therefore, there an urgent need real-world, long-term data. Methods In 2018, the Belgian government initiated nationwide secure platform follow-up all new existing therapies. This unique approach used...
Colonoscopy is associated with discomfort that requires intravenous sedation (IVS). The aim of this randomized controlled trial (RCT) was to explore the feasibility virtual reality distraction (VRD) for colonoscopy using two primary endpoints: cecal intubation rate and rescue IVS. Patients scheduled elective IVS were in a 2:1 ratio favor VRD, by propofol if needed. VRD involved use device providing visual auditive experience similar clinical hypnosis. Ninety patients included (VRD:60, IVS:...
Objective: We assessed whether or not pain relief could be achieved with a new system that combines 3D augmented reality (3DARS) and the principles of mirror visual feedback. Methods: Twenty-two patients between 18 75 years age who suffered chronic neuropathic pain. Each patient performed five 3DARS sessions treatment 20 mins spread over period one week. The following parameters were assessed: (1) analogic scale after each session (2) McGill DN4 questionnaire completed before first 24 h last...
This was a prospective study evaluating the Pain Sensitivity Questionnaire (PSQ) in 110 patients undergoing spine surgery.The purpose of this to compare ability PSQ-total and PSQ-minor scores with Catastrophizing Scale (PCS) predicting immediate postoperative pain after spinal surgery their risk developing chronically painful state.Studies PSQ as preoperative determinant for development chronic are lacking. Therefore, we undertook following study.Patients lumbar or cervical were...
Abstract Background The aim of this multicenter randomized interventional prospective study was to compare the ultrasound (US)-guided lumbar medial branch block (LMBB) with fluoroscopy (FS)-guided LMBB in terms analgesic efficacy and disability setting treatment pain arising from facet joints (LFJ). Methods Fifty adults a “LFJ” syndrome were into two groups: group FS, fluoroscopic-guidance used at three levels (L3-L4, L4-L5 L5-S1); US, same blocks performed under ultrasound. Needle...
Purpose To study the long-term evolution of patients with lower-limb Complex Regional Pain Syndrome (CRPS), focusing on functional and proprioceptive aspects quality life.Methods In 20 suffering from chronic distal CRPS diagnosed using Budapest criteria, we assessed joint position sense strength knee muscles at unaffected leg, exercise capacity, pain, severity score, life kinesiophobia. Similar assessments were performed in age-matched controls.Results The performance (at 45°) was...
BACKGROUND Sugammadex allows for rapid reversal of muscle relaxation after the use rocuronium or vecuronium. The lowest recommended dose is 2 mg kg −1 intravenously when there are two twitches during train-of-four stimulation. OBJECTIVE To study efficacy and risks a lower sugammadex administered earlier. DESIGN Monocentric randomised controlled double-blind study. SETTING Academic hospital. PATIENTS Eighty patients were enrolled in 8 groups 10 patients, 56 finally evaluated. INTERVENTIONS...
<title>Abstract</title> The aim of the study was to examine various haemostasis values identify most relevant biological indicators for detecting significant hemorrhage, determine effectiveness fresh frozen plasma (FFP) transfusion. Our findings suggest that a low prothrombin time, elevated Von Willebrand Antigen, increased fibrinogen, and reduced Ca2+ levels are associated with challenges in achieving proper hemostasis. However, measurements factors II, V, VII, VIII, IX, X, XI, XIII,...
The aim of the study was to examine various haemostasis values identify most relevant biological indicators for detecting significant haemorrhage, determine effectiveness fresh frozen plasma (FFP) transfusion. Our findings suggest that a low prothrombin time, elevated Von Willebrand Antigen, increased fibrinogen, and reduced Ca2 + levels are associated with challenges in achieving proper haemostasis. However, measurements factors II, V, VII, VIII, IX, X, XI, XIII, protein C, S do not appear...
Background: To improve patient comfort during gastroscopy, sedation is essential. Propofol can cause adverse effects if underdosed or overdosed. Lidocaine has been suggested as an adjuvant to propofol in this context. Objectives: This study aimed evaluate consumption when adding intravenous lidocaine gastroscopy. We also assessed whether reduces the associated with inappropriate sedation. Design: Prospective, randomised, controlled, double-blind, single-centre trial. Setting: Day hospital of...
Background: Etomidate is a hypnotic agent frequently used to induce general anaesthesia, primarily in frail patients and emergency situations. The depth of etomidate-induced anaesthesia healthy currently poorly studied. Objectives: purpose this study was evaluate the duration by bispectral analysis electroencephalogram following administration an induction dose etomidate, combined with remifentanil. We also aimed gain insight into attitudes French-speaking-Belgian anaesthesiologists...
Background: One of the reasons that high-frequency jet ventilation (HFJV) is used due to near immobility thoracic structures. However, no study has quantified movements cardiac structures during HFJV compared with normal mechanical ventilation. Methods: After ethical approval and written informed consent, we included 21 patients scheduled for atrial fibrillation ablation in this prospective crossover study. Each patient was ventilated both HFJV. During each mode, displacements structure were...