A5091014703- COVID-19 and healthcare impacts
- Reproductive Biology and Fertility
- Advanced Statistical Methods and Models
- Ovarian function and disorders
- SARS-CoV-2 and COVID-19 Research
- Long-Term Effects of COVID-19
- Pain Management and Opioid Use
- COVID-19 Clinical Research Studies
- Anesthesia and Pain Management
- Crustacean biology and ecology
- Animal Behavior and Welfare Studies
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Sperm and Testicular Function
- Reproductive Health and Technologies
- Cardiac, Anesthesia and Surgical Outcomes
- Renal function and acid-base balance
- Cancer Immunotherapy and Biomarkers
- Knee injuries and reconstruction techniques
- Electrolyte and hormonal disorders
- Aquaculture Nutrition and Growth
- Emergency and Acute Care Studies
- Sepsis Diagnosis and Treatment
- Cephalopods and Marine Biology
- Sports injuries and prevention
- Advanced Statistical Process Monitoring
Antwerp University Hospital
2013-2025
University of Antwerp
2010-2024
Statistics Belgium
2015-2023
Universitair Ziekenhuis Leuven
2019
University College Odisee
2015-2016
Newcastle University
2012-2014
Royal Bank of Canada
2010
University of Toronto
2010
Ghent University
2006-2008
Research on intravenous fluid therapy and its side effects, volume, sodium, chloride overload, has focused almost exclusively the resuscitation setting. We aimed to quantify all sources in ICU assess creep, hidden unintentional volume administered as a vehicle for medication or electrolytes.We precisely recorded burdens imposed by every source 14,654 patients during cumulative 103,098 days they resided our 45-bed tertiary simulated impact of important strategic choices patients' burdens. In...
To investigate impacts of practice environment factors and burnout at the nursing unit level on job outcomes nurse-assessed quality care in acute hospital nurses.Prior research has consistently demonstrated correlations between nurse environments nurses' satisfaction health work, but somewhat less evidence connects with patient outcomes. The relationship also been more extensively documented using hospital-wide measures as opposed to level.Survey.Data from a sample 546 staff nurses 42 units...
Cancer patients are at a higher risk of developing severe coronavirus disease 2019 (COVID-19). However, the safety and efficacy COVID-19 vaccination in cancer undergoing treatment remain unclear.In this interventional prospective multicohort study, priming booster doses BNT162b2 vaccine were administered 21 days apart to solid tumor receiving chemotherapy, immunotherapy, targeted or hormonal therapy, with hematologic malignancy rituximab after allogeneic hematopoietic stem cell...
Introduction Despite advances in immunomodulatory treatments of multiple sclerosis (MS), patients with non-active progressive (PMS) continue to face a significant unmet need. Demyelination, smoldering inflammation and neurodegeneration are important drivers disability progression that insufficiently targeted by current treatment approaches. Promising preclinical data support repurposing metformin for PMS. The objective this clinical trial is evaluate whether metformin, as add-on treatment,...
Aim The aim of this study was to investigate if intervention targeting breath support, phonation, and speech rate increases intelligibility participation in the conversational interactions younger children with dysarthria cerebral palsy ( CP ). Method Fifteen (nine males, six females; age range 5–11y, mean 8y, SD 2y; type: eight spastic, four dyskinetic, one ataxia, two W orster D rought syndrome; G ross M otor F unction C lassification S ystem levels II – IV , median level ) participated...
Daily and globally, millions of adult hospitalized patients are exposed to maintenance i.v. fluid solutions supported by limited scientific evidence. In particular, it remains unclear whether tonicity contributes the recently established detrimental effects fluid, sodium, chloride overload.This crossover study consisted two 48 h periods, during which 12 fasting healthy adults were treated with a frequently prescribed solution (NaCl 0.9% in glucose 5% supplemented 40 mmol litre -1 potassium...
To determine the effects of sodium content maintenance fluid therapy on cumulative balance and electrolyte disorders. We performed a randomized controlled trial adults undergoing major thoracic surgery, randomly assigned (1:1) to receive fluids containing 154 mmol/L (Na154) or 54 (Na54) from start surgery until their discharge ICU, occurrence serious adverse event third postoperative day at latest. Investigators, caregivers patients were blinded treatment. Primary outcome was balance....
We investigated whether a web-based cognitive training video game is an effective approach to improve decline in combination with our standard of care for rehabilitation breast cancer (BC) patients.Self-selected BC patients between 18 and 71 years old complaining disturbing impairment were studied. The received access internet online assessments (Aquasnap, Cambridge, MyCQ™). early intervention group (n = 23) had program 6 months at least three times week minimum 60 min playing per home...
Introduction Spinal cord stimulation is a common treatment option for neuropathic pain conditions. Despite its extensive use and multiple technological evolutions, long term efficacy of spinal debated. Most studies on include rather limited number patients and/or follow-ups over period. Therefore, there an urgent need real-world, long-term data. Methods In 2018, the Belgian government initiated nationwide secure platform follow-up all new existing therapies. This unique approach used...
The level of protection against SARS-CoV-2 breakthrough infections conferred by the presence anti-S1 antibodies (IgGs) in cancer patients is still understudied. This work examines existence an immunoglobulin G (IgG) -based correlate (CoP) established prospectively collected observational data about with different variants a large cohort study vaccinated patients. 760 were longitudinally followed-up, starting before first vaccination until six months after second booster. Anti-S1 IgGs...
Abstract Introduction: Long COVID is defined as the continuation of symptoms, unexplainable by alternative diagnosis, longer than four weeks after SARS-CoV-2 infection. These symptoms might hinder daily activities and overall well-being, ultimately impacting quality life (QoL). Several studies have reported fatigue most common symptom, followed dyspnoea, headache myalgia. Although it assumed that long affects 10–20% infected individuals, recently numbers up to 60% were described for patients...
Malignant pleural mesothelioma (MPM) is an aggressive cancer with a very poor prognosis. Recently, immune checkpoint inhibition (ICI) has taken center stage in the currently ongoing revolution that changing standard-of-care treatment for several malignancies, including MPM. As multiple arguments and accumulating lines of evidence are support existence therapeutic synergism between chemotherapy immunotherapy, as well different classes immunotherapeutics, we designed multicenter, single-arm,...
Objective The Montreal Cognitive Assessment (MoCA) is a sensitive and clinically practical test but its usefulness in measuring long‐term cognitive effects of ECT unclear. Using the MoCA, we investigated short‐ global change ECT‐treated patients with Major Depressive Episode (MDE). Method We included 65 consecutive MDE, whom functioning was assessed at baseline (T0); during (before third session; T1); 1 week (T2), 3 months (T3), 6 (T4) after completion index course. Changes MoCA (sub)scores...