Both left-handed and right-handed helical chains of [(VO2)(HPO4)]∞, which are linked by [M(4,4′-bpy)2] to form three-dimensional framework structures (see picture), present in the two novel inorganic–organic hybrid materials, [M(4,4′-bpy)2(VO2)2(HPO4)4]. These were prepared from hydrothermal systems characterized single-crystal X-ray diffraction. M=Co or Ni; bpy=bipyridine.

Pine needle oil from crude extract of pine needles has been used as an anti-cancer agent in Traditional Chinese Medicine. The α-pinene is a natural compound isolated which shown activity. In previous study, we found that exhibited significant inhibitory effect on hepatoma carcinoma BEL-7402 cells. this investigate the inhibition cells vitro and vivo further explore mechanism. results show liver cancer cell growth was inhibited obviously with rate 79.3% 69.1% vivo, Chk1 Chk2 levels were...

By using the mixed-linker strategy, a new pillar-layered luminescence Zn-LMOF (JLU-MOF71) ([Zn2Na2(TPHC)(4,4-Bipy)(DMF)]·8H2O) (TPHC = [1,1':2',1″-terphenyl]-3,3″,4,4',4″,5'-hexacarboxylic acid, 4,4-bipy 4,4-bipyridine, DMF N, N-dimethylformamide) was successfully synthesized and structurally characterized. JLU-MOF71 is constructed by pillars 2D layers which consist of Zn2+ TPHC ligands, displays rare fsh topology. Benefiting from uncoordinated carboxylate sites in framework, not only can...

Osteosarcoma is a malignant musculoskeletal tumor that has high-rate morbidity and mortality worldwide. Alginate oligosaccharide (AOS), natural product, antitumor activities may have therapeutic effects in osteosarcoma, the molecular mechanisms of which remain unclear. AOS was prepared from alginate sodium using lyase. The fractions were further isolated by size-exclusion chromatography verified electrospray ionization mass spectrometry (ESI-MS). patients enrolled study assigned into two...

A novel metal-organic framework, [(CH3)2NH2]2[Cu3O(SO4)3Cu2L2(DMF)(H2O)]·9DMF (JLU-Liu39) H2L = pyridine-3,5-bis(phenyl-4-carboxylic acid), has been successfully synthesized under solvothermal conditions. Structure analysis indicates that the framework of JLU-Liu39 is constructed by ternary building units which include a rare hexa-nuclear [Cu6O2(SO4)6] cluster, classical [Cu2(CO2)4] paddlewheel, and 3-connected hetero-N, O donor ligand. The whole 3D possesses (3,4,4)-connected fjh topology...

Distinct from predominately known fluorescence quenching (turn-off) detection, turn-on response to hazardous substances by luminescent metal–organic frameworks (LMOFs) could greatly avoid signal loss and susceptibility environmental stimulus. However, such detection rarely occurs lacks theoretical elucidations. Here, we present the first example of unique unprecedented turn-off–on responses a variety acids stable 12-connected hexanuclear Y(III)-cluster-based LMOF material─JLU-MOF111,...

The use of porous solid adsorbents is an effective and excellent approach for the separation purification methanol-to-olefins product methane (CH4). In this particular study, a series adenine (AD)-based biological metal–organic frameworks (Bio-MOFs) {Their general formula Cu 2 (AD) (X) [X = formic acid, acetic acid (AA), propionic acid]} were proposed, which exhibited remarkable efficiency in CH4 C3H6 from product, ultimately yielding purified C2H4. experimental findings demonstrate that...

Two new metal–organic frameworks [Cd3(H2O)2(C5N2O4H)2·H2O] 1 and [KCd(C7N2O4H5)] 2 have been hydrothermally synthesized employing 4,5-imidazoledicarboxylic acid (IMDC) 2-ethyl-4,5-imidazoledicarboxylic (2-EtIMDC) as organic ligands. The single-crystal structure analysis reveals that compound exhibits a 3-D framework, which is generated from 2-D layers pillared by 1-D chains along the c-axis. Compound presents with channels, are connected in cross-like fashion [CdN2O3] trigonal bipyramid...

Four novel zinc(II) metal-organic frameworks, {[Zn7(trz)6(1,3-bdc)4(H2O)2]·2H2O}n (1), {[Zn7(trz)6(hip)4(H2O)2]·8H2O}n (2), [Zn4(trz)4(Hnip)2(nip)]n (3), and [Zn5(trz)2(Hbtc)4(H2O)4]n (4) (Htrz = 1,2,4-triazole, 1,3-H2bdc 1,3-benzenedicarboxylic acid, H2hip 5-hydroxyisophthalic H2nip 5-nitroisophthalic H3btc 1,3,5-benzenetricarboxylic acid), have been hydrothermally synthesized by reaction of Zn salt Htrz with four different aromatic acids, respectively. Their structures were determined...

Two highly porous MOFs, [Co2(μ2-OH)(bpdc)(Htpim)2][SiF6]·3.5DMA·2.5CH3OH (JLU-Liu37, H2bpdc = biphenyl-4,4′-dicarboxylate, Htpim 2,4,5-tri(4-pyridyl)imidazole) and [Ni2(μ2-OH)(bpdc)(Htpim)2][SiF6]·7.5DMA·6CH3OH (JLU-Liu38), have been solvothermally synthesized by using the mixed ligand strategy. Both of compounds possess finite binuclear [M2(μ2-OH)(COO)2] (M Co, Ni) secondary building units (SBUs) which formed with a polar functional group, μ2-OH. JLU-Liu37 JLU-Liu38 exhibit notable...

Osteoporosis is a chronic disease whose symptoms include reduction in bone strength, osteopenia, and damage to the microstructure. Ferulic acids are natural polyphenols present various fruits that suppress fusion apoptosis of mature osteoclasts. Rats were divided into sham, control (osteoporosis), 10 mg/kg body weight ferulic acid, 20 30 acid treatment groups. was induced neonatal by administration dexamethasone (glucocorticoids). Bone mineral density (BMD), osteocalcin alkaline phosphatase...

Here, a Y(III)-based metal-organic framework, JLU-MOF112 {[Y3(μ3-O)2(μ3-OH)(H2O)2(BTCTBA)2]·2[(CH3)2NH2]·5DMF·C6H5Cl·4H2O}, has been successfully synthesized under solvothermal conditions. was constructed with amide-functionalized tricarboxylate ligands and infinite chains, where the Y3 repeating units are arranged in trans order. The overall framework could be viewed as novel (3,5)-connected net two types of channels along [100] [010] directions. possesses large BET surface area (1553 m2...

The assembly of Cu(CH3COO)2·H2O and pyridine-4,5-imidazoledicarboxylic acid (H3PyImDC) under solvothermal conditions in the presence different organic templates yielded two three-dimensional chiral frameworks, |(C3H10N2)(C3H7NO)0.5(H2O)2|[CuIIC10H5O4N3] (1) |(C4H9NO)0.5(H2O)8|[CuII2CuI(C10H5O4N3)2(C10H6O4N3)] (2). Both compounds crystallized cubic, P4332 space group possessed open helical channels frameworks. To best our knowledge, 1 2 present first synthesized MOFs with a bmn lcy-a net....

A luminescent MOF was constructed by employing a mixed ligands strategy and may be used as potential probe for the detection of acetone.

To further reveal the extraction model for selective separation of trivalent actinides over lanthanides by dithiophosphinic acids (DPAHs), five representative DPAH ligands with different substituent groups have been synthesized, and their complexation behaviors toward Am3+/Eu3+ investigated both experimentally theoretically. The introduction electron-withdrawing group −CF3 into is beneficial to extractability among ligands. Slope analyses show that Am3+ Eu3+ were extracted as...

We explored the effects of chitosan oligosaccharides (COS) on coronary heart disease (CHD) patients. The component COS was measured by matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS). CHD patients were evenly assigned into group (COG) and placebo (CG). duration treatment 6 months therapeutic results measuring left ventricular ejection fraction (LVEF) value, Lee scores, quality life (QOL), blood urea nitrogen, serum creatinine. intestinal flora...

Two coordination polymers of {[Mn(maleate)(μ-4,4'-bipy)]·0.5(H2O)}∞ (1) and {[Mn(fumarate)(μ-4,4'-bipy)(H2O)]·0.5(4,4'-bipy)}∞ (2) (bipy = bipyridine) were synthesized structurally characterized. The 1-D [Mn(maleate)]8 chains formed by maleate molecules chelating Mn atoms, these connected with 4,4'-bipy to form a 2-D structure (structure 1). [Mn(fumarate)(H2O)]∞ layers composed the fumarate coordinating different ions, linked give 3-D open framework 2).

Two novel porous MOFs, [Zn5(DpImDC)2(DMF)4(H2O)3]·H2O·DMF (JLU-MOF48, H5DpImDC = 2-(3,5-dicarboxyphenyl)-1H-imidazole-4,5-dicarboxylic acid) and [Co5(DpImDC)2(DMF)4(H2O)6]·DMF (JLU-MOF49), have been solvothermally synthesized by using a ligand consisting of 4,5-imidazoledicarboxylic acid part an isophthalic part. compounds similar structures connections, but with significant differences in symmetry (monoclinic orthorhombic) due the cis–trans isomerism mononuclear metal node. Moreover,...