A5002735817- Bladder and Urothelial Cancer Treatments
- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Urinary and Genital Oncology Studies
- Frailty in Older Adults
- Urinary Bladder and Prostate Research
- Renal cell carcinoma treatment
- Urological Disorders and Treatments
- Cancer, Lipids, and Metabolism
- Testicular diseases and treatments
- Esophageal Cancer Research and Treatment
- Renal and Vascular Pathologies
- Organ Donation and Transplantation
- Renal Transplantation Outcomes and Treatments
- Organ and Tissue Transplantation Research
- Sperm and Testicular Function
- Multiple and Secondary Primary Cancers
- Nutrition and Health in Aging
- Renal and related cancers
- Urologic and reproductive health conditions
- Chronic Kidney Disease and Diabetes
- Kidney Stones and Urolithiasis Treatments
- Adrenal and Paraganglionic Tumors
- Genital Health and Disease
- Cancer Genomics and Diagnostics
Hirosaki University
2013-2023
Towada City Hospital
2023
Miyagi Prefectural Hospital Organization
2020
La Jolla Alcohol Research
2020
United States Department of Veterans Affairs
2018
Providence College
2018
BackgroundNeoadjuvant chemotherapy (NAC) use for patients with locally advanced upper tract urothelial carcinoma (UTUC) is debatable.ObjectiveTo investigate the efficacy and safety of platinum-based NAC UTUC.Design, settings, participantsOf 233 consecutive who underwent radical nephroureterectomy, 55 received (NAC group) 138 did not (Ctrl group).Outcome measurements statistical analysisThe two arms vs NAC) were matched using propensity scores to minimize selection bias. We retrospectively...
Abstract Background Management of renal cell carcinoma (RCC) with tumor thrombus extending to the vein and inferior vena cava (IVC) is challenging. The aim this study was evaluate benefit surgical management in such patients. Methods From February 1995 2013, 520 patients were treated for RCC at Hirosaki University Hospital, Hirosaki, Japan. (n = 42) IVC 43) included study. records these 85 retrospectively reviewed assess relevant clinical pathological variables survival. Prognostic factors...
Abstract Objectives To evaluate the relationship between frailty and lower urinary tract symptoms (LUTS), association of LUTS remains unclear. Methods This cross‐sectional study investigated in 710 individuals (249 men 461 women, aged ≥60 years) who participated Iwaki Health Promotion Project 2014 2015 Hirosaki, Japan. Parameters were compared for with mild moderate to severe LUTS. The International Prostate Symptom Score (IPSS) Overactive Bladder (OABSS) used Frailty was evaluated by...
Objectives To evaluate the association between score of Geriatric 8 screening tool and treatment by disease stages in patients with prostate cancer. Methods Between January 2017 June 2019, we prospectively evaluated 540 cancer who were treated robot‐assisted radical prostatectomy, radiotherapy, androgen deprivation therapy alone standard care for metastatic hormone‐naïve or castration‐resistant The primary purpose was frailty (Geriatric ≤14) alone, diseases. Secondary purposes included a...
// Itsuto Hamano 1 , Shingo Hatakeyama Hiromichi Iwamura Naoki Fujita Ken Fukushi Takuma Narita Kazuhisa Hagiwara Ayumu Kusaka Shogo Hosogoe Hayato Yamamoto Yuki Tobisawa Tohru Yoneyama 2 Takahiro Yasuhiro Hashimoto Takuya Koie Hiroyuki Ito 3 Kazuaki Yoshikawa 4 Toshiaki Kawaguchi 5 and Chikara Ohyama 1, Department of Urology, Hirosaki University Graduate School Medicine, Hirosaki, Japan Advanced Transplant Regenerative Aomori Rosai Hospital, Hachinohe, Mutsu General Mutsu, Prefectural...
The incidence of secondary neoplasms the testis during autopsies is approximately 2.5%. Although most testicular metastases are due to prostate cancer, only a few patients with cancer have clinically manifested metastasis. We report case patient metastasis who was diagnosed after presence palpable mass in right testis. A 56-year-old Japanese male presented our hospital an elevated serum prostate-specific antigen (PSA) level 137 ng/ml. He stage IV (T3N1M1b) and received androgen deprivation...
The benefits of novel androgen receptor axis-targeted agents (ARATs) on oncological outcomes in patients with non-metastatic castration-resistant prostate cancer (nmCRPC) real-world settings are unclear.
Objectives To evaluate the effect of pretreatment C‐reactive protein/albumin ratio and modified Glasgow prognostic score on prognosis in patients with metastatic renal cell carcinoma. Methods A retrospective study was carried out 176 carcinoma who received first‐line tyrosine kinase inhibitors. The adding inflammatory scores to International Metastatic Renal Cell Carcinoma Database Consortium model (International Consortium‐C‐reactive Consortium‐Glasgow models) overall survival evaluated...
Objectives To evaluate the association of tumor burden with prognosis in real‐world patients metastatic castration‐sensitive prostate cancer and to investigate eligibility for upfront intensification therapy. Methods We retrospectively evaluated 679 who were initially treated conventional androgen deprivation therapy between August 2001 November 2018. The primary purpose was based on progression castration‐resistant cancer. secondary included comparison rate, cancer‐free survival overall...
Objectives To determine the influence of serum uric acid (UA) levels on renal impairment in patients with UA stone. Materials and methods We retrospectively analyzed 463 calcium oxalate and/or phosphate stones (CaOx/CaP), 139 stones. The subjects were divided into UA-high (UA ≥ 7.0 mg/dL) or UA-low group < mg/dL). control comprised 3082 community-dwelling individuals that pair-matched according to age, sex, body mass index, comorbidities, hemoglobin, albumin, using propensity score matching....
The aim of the present study is to investigate clinical relevance aortic calcification in urolithiasis patients. Between January 2010 and September 2014, 1221 patients with were treated Oyokyo Kidney Research Institute Hirosaki University Hospital. Among these, 287 (Stone group) on whom adequate data available included this retrospective study. We also selected 148 subjects early stage (pT1N0M0) renal cell carcinoma from 607 who underwent radical nephrectomy at Hospital (Non-stone as control...
To evaluate the impact of preoperative chronic kidney disease (CKD) on oncological outcomes in patients with upper tract urothelial carcinoma who underwent radical nephroureterectomy.A total 426 nephroureterectomy at five medical centers between February 1995 and 2017 were retrospectively examined. Oncological outcomes, including intravesical recurrence-free, visceral cancer-specific, overall survival rates (intravesical RFS, CSS, OS, respectively) stratified by CKD status (CKD vs. non-CKD)...
Although oncologic testicular sperm extraction (onco-TESE) has been increasingly practiced, the evidence of onco-TESE performed in patients with cancer is insufficient. Furthermore, bilateral cancer, accounting for 0.5%-1% cancers, more challenging and insufficiently reported.Here we report case a 25-year-old man who underwent from his residual single testis nonseminomatous germ cell tumor that occurred 5 years after orchiectomy contralateral testis. A second simultaneous TESE noncancerous...
Objectives To investigate the effect of frailty on type urinary diversion after radical cystectomy in patients with muscle‐invasive bladder cancer. Methods Between January 2014 and 2020, we prospectively evaluated 88 localized cancer, who had received diversion. The selection was determined by operating surgeon based performance status, comorbidities, tumor status patient’s preference. evaluation included Fried phenotype criteria, modified index discriminant score. We investigated...
To investigate the association of pain with frailty in patients localized prostate cancer (PC) who underwent robot-assisted laparoscopic radical prostatectomy (RARP).Between January 2017 and June 2019, we prospectively evaluated geriatric 8 (G8) score, simplified index (sFI), numerical rating scale (NRS) 154 PC RARP at our institution. NRS was measured on preoperative day 0, postoperative days 1, 2, 3, discharge. Moderate to severe defined as ≥ 5, whereas G8 ≤ 14. The primary objectives this...
Abstract Objectives To evaluate the effect of overactive bladder (OAB) and frailty on indoor fall events in community‐dwelling adults aged 50 or older. Methods We conducted a cross‐sectional study involving 723 between 2016 2017 Hirosaki, Japan. OAB symptoms sleep disturbance were assessed using Overactive Bladder Symptom Score (OABSS) Pittsburgh Sleep Quality Index (PSQI). Indoor (falls near‐falls) within 1 year evaluated. Frailty was evaluated by discriminant score. investigated...
We aimed to investigate the association of frailty with treatment selection in patients muscle-invasive bladder cancer (MIBC) as is one key factors for modality selection.We retrospectively evaluated 169 MIBC from January 2014 September 2020 using Fried phenotype, modified index, and discriminant score. The primary purpose was comparing between who underwent radical cystectomy (RC) those had trimodal therapy (TMT) preservation. Secondary purposes were groups effect TMT on overall survival...
Although the number of elderly patients requiring dialysis has increased, data regarding prognosis undergoing hemodialysis are limited. In present study, in Japanese aged ≥80 years was evaluated. From January 1988 to July 2013, 1144 consecutive with end‐stage renal disease required replacement therapy at our institution; these, 141 were years. These patients’ charts retrospectively reviewed for relevant clinical variables and survival time. The life expectancies table from National Vital...