A5024510570- Spinal Fractures and Fixation Techniques
- Scoliosis diagnosis and treatment
- Spine and Intervertebral Disc Pathology
- Vascular Malformations Diagnosis and Treatment
- Pelvic and Acetabular Injuries
- Peripheral Artery Disease Management
- Intracerebral and Subarachnoid Hemorrhage Research
- Medical Imaging and Analysis
- Surgical Simulation and Training
- Cervical and Thoracic Myelopathy
- Cerebral Venous Sinus Thrombosis
- Cardiac, Anesthesia and Surgical Outcomes
- Pain Management and Treatment
- Epilepsy research and treatment
- Neurosurgical Procedures and Complications
- History of Medical Practice
- Traumatic Brain Injury and Neurovascular Disturbances
- Inflammatory Myopathies and Dermatomyositis
- Management of metastatic bone disease
- Spinal Hematomas and Complications
- Musculoskeletal pain and rehabilitation
- Acute Ischemic Stroke Management
- Intraoperative Neuromonitoring and Anesthetic Effects
- Takotsubo Cardiomyopathy and Associated Phenomena
- Airway Management and Intubation Techniques
University of California, San Diego
2020-2025
Neurological Surgery
2020-2025
Université Bourgogne Franche-Comté
2025
Primary Source
2023
University of Florida
2023
UC San Diego Health System
2022-2023
Lurie Children's Hospital
2023
Northwestern University
2023
St. Luke's University Health Network
2017-2021
University of San Diego
2021
BACKGROUND Effective decompression, arthrodesis, and correction of spinal conditions frequently utilize operative approaches that expose both the anterior posterior column. Until now, circumferential column access often requires surgeon to reposition drape patient multiple times or a only approach has limited capability lateral-only complicates otherwise traditional surgical maneuvers. OBJECTIVE To describe technique utilizing single position enables minimally disruptive with simultaneous...
OBJECTIVE The aim of this paper was to evaluate the changes in radiographic spinopelvic parameters a large cohort patients undergoing prone transpsoas approach lumbar spine. METHODS A multicenter retrospective observational study performed for all who underwent lateral lumber interbody fusion via single-position (PTP) approach. Spinopelvic from preoperative and first upright postoperative radiographs were collected, including lordosis (LL), pelvic incidence (PI), tilt (PT). Functional...
Patients with peripheral artery disease (PAD) and diabetes constitute a high risk population for development of critical limb ischemia (CLI) amputation, although the underlying mechanisms remain poorly understood.Comparison dysregulated microRNAs from diabetic human subjects PAD mice revealed conserved microRNA, miR-130b-3p. In vitro angiogenic assays demonstrated miR-130b rapidly promoted proliferation, migration, sprouting in endothelial cells (ECs), whereas inhibition exerted...
Dr. Joan Venes (1935-2010) is a well-respected pioneer of pediatric neurosurgery. She was the third board-certified female neurosurgeon in United States and first neurosurgery resident to be accepted by her residency program at Yale University. recipient numerous awards, including prestigious Van Wagenen Fellowship, which sparked interest furthering research around intracranial pressure monitoring. Throughout career, prolific researcher, publishing extensively on shunts, procedural...
INTRODUCTION: Patient specific rods (PSRs) are pre-bent to post-spinal fusion sagittal alignment goals. Adult idiopathic and degenerative scoliosis cause large rigid coronal deformities. Whether a sagittaly-derived PSR detracts from correction is unknown. METHODS: Patients > 18 years-old with idiopathic/degenerative receiving posterior instrumented single surgeon/single institution were reviewed. Prior fusions 2 levels excluded; >6 using PSRs UIV/LIV greater than T1/L1 included. All...
INTRODUCTION: Recent studies suggest L4-S1 lordosis is similar across individuals whereas lumbar (LL) differs by sagittal shape classification. Pre-bent rods account for both parameters. METHODS: Patients >18 years old with idiopathic or degenerative scoliosis receiving posterior instrumented fusion from a single surgeon/single institution were reviewed. Those fused >6 levels LIV at the sacrum/pelvis, PCOs, and PSRs included. Revision cases excluded. Demographics, operative/inpatient...
(1) Background: The correction of adult spinal deformity (ASD) can require long, complex constructs with multiple rods which traverse important biomechanical levels to achieve multi-pelvic fixation. Minimally invasive (MIS) placement these has historically been difficult. Advanced technologies such as robotics platforms facilitate the design and further enable surgical approaches in MIS surgery. (2) Methods: A retrospective study was performed on a series ASD patients undergoing ≥eight...
Study Design Retrospective cohort study. Objectives Preoperative risk stratification using frailty is common for adults but difficult to apply pediatric populations. We aimed identify factors indicating physiologic vulnerability and predict perioperative complications in children with neuromuscular scoliosis (NMS) create a prediction model physiological (PV-5). Methods Patients NMS were identified from the American College of Surgeons National Surgical Quality Improvement Program Pediatric...
AIMTo investigate the occurrence of cardiomyopathy (CMP) in a cohort patients with histologically proven pheochromocytoma (pheo), and to determine if catecholamine excess was causative left ventricular (LV) dysfunction. CONCLUSIONThis study adds growing body literature on predilection pheochromocytomas develop non-ischemic CMP.Degree as measured by urinary secretion metabolites did not predict development CMP but 2 3 developed setting significant acute physiologic stress.Our findings provide...
Abstract Purpose There is limited information on the clustering or co-occurrence of complications after spinal fusion surgery for neuromuscular disease in children. We aimed to identify frequency and predictive factors co-occurring perioperative these Methods In this retrospective database cohort study, we identified children (ages 10–18 years) with scoliosis who underwent elective 2012–2020 from National Surgical Quality Improvement Program-Pediatric database. The rates within 30 days were...
Chronic kidney disease (CKD) causes accumulation of uremic metabolites that negatively affect skeletal muscle. Tryptophan-derived are agonists the aryl hydrocarbon receptor (AHR), which has been shown to be activated in CKD. This study investigated role AHR muscle pathology Compared with controls normal function, AHR-dependent gene expression (CYP1A1 and CYP1B1) was significantly upregulated patients CKD, magnitude activation inversely correlated mitochondrial respiration. In mice oxidative...
Retrospective.
Prone transposoas (PTP) is a novel approach to the lateral lumbar interbody fusion that harnesses advantages of minimally invasive surgery with circumferential access spine in single position. We present peri-operative course four index cases patients having undergone PTP at institution.Pre and post-operative spinal imaging alignment parameters, operative approach, patient outcome are reviewed for each case.As advances neuromonitoring technology continue evolve, new approaches becoming...
The institution-wide response of the University California San Diego Health system to 2019 novel coronavirus disease (COVID-19) pandemic was founded on rapid development in-house testing capacity, optimization personal protective equipment usage, expansion intensive care unit analytic dashboards for monitoring institutional status, and implementation an operating room (OR) triage plan that postponed nonessential/elective procedures. We analyzed impact this only academic neurosurgery center...
Retrospective cohort.To examine SRS-Self Image scores at up to 10 years after surgery for adolescent idiopathic scoliosis (AIS).Self-image is complex with implications surgical and patient-reported outcomes AIS surgery. Surgically modifiable factors that impact self-image are inconsistently reported in the literature few longer-term reports. We examined rate durability of improvement.An registry was queried patients follow-up A mixed effects model estimated change SRS-22 Self from baseline 6...
INTRODUCTION: Both the prone transpsoas (PTP) and standard LLIF have been developed to facilitate minimally invasive (MIS) indirect decompression, alignment correction, posterior instrumentation. METHODS: A multi-center cohort of all patients was identified relevant data were retrospectively collected. Preoperative standing 36” scoliosis radiographs reviewed for pelvic incidence (PI), lumbar lordosis (LL), PI minus LL (PI-LL mismatch). Postoperative regional sagittal parameters measured...
Retrospective registry analysis.
BACKGROUND: Chronic kidney disease (CKD) has emerged as a significant risk factor that accelerates atherosclerosis, decreases muscle function, and increases the of amputation or death in patients with peripheral artery (PAD). However, modulators underlying this exacerbated pathobiology are ill-defined. Recent work demonstrated uremic toxins associated limb PAD have pathological effects both vasculature. Herein, we utilize multiomics to identify novel CKD. METHODS: A cross-sectional study...
The unique anatomy at L5-S1 presents different challenges and considerations to be made when compared other areas in the lumbar spine. In this way, oblique interbody fusion (OLIF) is more closely related a supine anterior (ALIF) except that former performed lateral position down smaller minimally invasive retroperitoneal corridor. This positioning L5-S1, however, provides an opportunity for single-position surgery simultaneously with posterior fixation, which not afforded by approaches. We...
The lateral lumbar interbody fusion has evolved as newly envisioned access corridors become feasible with technological advances. Prone a single-access approach to combine the benefits of minimally invasive surgery direct and indirect decompression neural elements synergistic anterior posterior column correction. In this video, authors discuss pearls, pitfalls, adjuvant technologies they use in high-volume prone center via case demonstration corpectomy. video can be found here:...
Lewis, Courtney S. BS; Stone, Lauren E. MD; Forseth, Kiefer J. MD PhD; Pham, Martin H. Author Information