- Scoliosis diagnosis and treatment
- Spinal Fractures and Fixation Techniques
- Spine and Intervertebral Disc Pathology
- Pelvic and Acetabular Injuries
- Hip disorders and treatments
- Cerebral Palsy and Movement Disorders
- Connective tissue disorders research
- Cardiac, Anesthesia and Surgical Outcomes
- Intraoperative Neuromonitoring and Anesthetic Effects
- Medical Imaging and Analysis
- Shoulder Injury and Treatment
- Hip and Femur Fractures
- Bone fractures and treatments
- Surgical site infection prevention
- Spinal Dysraphism and Malformations
- Musculoskeletal pain and rehabilitation
- Botulinum Toxin and Related Neurological Disorders
- Congenital Diaphragmatic Hernia Studies
- Orthopedic Infections and Treatments
- Anesthesia and Pain Management
- Neurogenetic and Muscular Disorders Research
- Pleural and Pulmonary Diseases
- Shoulder and Clavicle Injuries
- Dupuytren's Contracture and Treatments
- Orthopedic Surgery and Rehabilitation
Nemours Children's Health System
2022-2025
Setting Scoliosis Straight Foundation
2014-2025
Case Western Reserve University
2025
Alfred I. duPont Hospital for Children
2015-2024
Dupont Hospital
2014-2024
Globus Medical (United States)
2016-2024
Pacira (United States)
2023-2024
Stryker (United States)
2016-2024
Memorial Sloan Kettering Cancer Center
2022-2024
Rogers (United States)
2024
Background: Previous reports have indicated high complication rates associated with non-fusion surgery in patients early-onset scoliosis. This study was performed to evaluate the clinical and radiographic complications growing-rod treatment. Methods: Data from multicenter Growing Spine Study Group database were evaluated. Inclusion criteria treatment for scoliosis a minimum of two years follow-up. Patients divided into groups according rod type (single or dual) location (subcutaneous...
Background: Despite the many reports attesting to efficacy of intraoperative somatosensory evoked potential monitoring in reducing prevalence iatrogenic spinal cord injury during corrective scoliosis surgery, these afferent neurophysiological signals can provide only indirect evidence motor tracts since they monitor posterior column function. Early on use transcranial electric potentials corticospinal directly suggested that method holds great promise for improving detection emerging injury....
A retrospective multicenter study.To evaluate the effect of repeated surgical lengthenings and time on spinal growth Cobb angle in children with early onset scoliosis dual growing rods.Previous studies have established effectiveness rods for controlling deformity promoting "growth." Although anecdotal experience suggests that decreases over time, this has not been previously studied.Medical records from five different centers were reviewed to identify treated who had a minimum 2-year...
In Brief Study Design. Retrospective review. Objective. To compare the incidence of and risk factors for proximal junctional kyphosis (PJK) in adolescent idiopathic scoliosis (AIS) following posterior spinal fusion using hook, pedicle screw, or hybrid constructs. Summary Background Data. Proximal is a recently recognized phenomenon adults adolescents after AIS surgery. The postoperative effect on PJK with use hooks, constructs, screws has not been compared multicenter study to date. Methods....
Retrospective multicenter review.Determine the definition, indications, results, and outcomes, focusing on complications of vertebral column resection (VCR) for severe pediatric spinal deformity.The strict definition VCR procedure, numerous, potentially serious are unknown or controversial, a large review has never been performed.A total 147 patients treated by 7 deformity surgeons were reviewed-seventy-four females 73 males, with an average age 13.7 years, 1.6 (range, 1-5) vertebrae...
Background: Despite the many reports attesting to efficacy of intraoperative somatosensory evoked potential monitoring in reducing prevalence iatrogenic spinal cord injury during corrective scoliosis surgery, these afferent neurophysiological signals can provide only indirect evidence motor tracts since they monitor posterior column function. Early on use transcranial electric potentials corticospinal directly suggested that method holds great promise for improving detection emerging injury....
Perioperative surgical site infection (SSI) after pediatric spine fusion is a recognized complication with rates between 0.5% and 1.6% in adolescent idiopathic scoliosis up to 22% "high risk" patients. Significant variation the approach prophylaxis has been well documented. The purpose of this initiative develop consensus-based "Best Practice" Guideline (BPG), informed by both available evidence literature expert opinion, for high-risk patients undergoing fusion. For effort, high risk was...
Review of a prospectively collected growing rod database.To define risk factors for and characterize the nature fractures.Rod fracture is common complication treatment. The project sought to analyze breakage develop preventive strategies.Records 327 patients in database were studied. Risk studied as patient-related rod-related. Multivariate analysis was performed.Eighty-six fractures occurred 49 (49 327, 15%). Sixteen had repeat with eight having more than two (maximum six). most locations...
Background: Single-surgeon series investigating the learning curve involved in surgery for spinal deformity may be confounded by changes technology and techniques. Our objective with this multicenter, prospective study was to present a cross-sectional analysis of impact surgeon experience on adolescent idiopathic scoliosis. Methods: All posterior-only surgical procedures scoliosis performed 2007 2008 academic year, minimum two years patient follow-up, were included. Two groups created basis...
Background: Spinal instrumentation in adolescent idiopathic scoliosis (AIS) aims to correct spinal deformity and maintain long-term stability until bony healing is ensured. The purpose of this study was compare the minimum 2-year postoperative radiographic clinical results posterior spine correction fusion with all-hook versus hybrid segmental pedicle screw for AIS from a single institution. Methods: A total 105 patients who underwent (35), hook or (35) were sorted matched according...
The nature of orthopaedic implant surfaces affects the interaction between bone and implant. To analyze this at a cellular level, study examined early phase cell adhesion to surfaces. Using an in vitro model, primary human osteoblasts cultured on Ti6A14V (Ti), CoCrMo (CC), tissue culture polystyrene (PS) was characterized. were found adhere greater numbers Ti compared with PS CC during 12 hour period. Other characteristics related adhesion, such as spreading, cytoskeletal organization, focal...
Summary of Background Data Growing rods are a commonly used form growth guidance for patients with early onset scoliosis, but no studies exist to characterize their use among large group surgeons. Methods A survey regarding growing rod preferences and case-based scoliosis were completed by an international Two hundred sixty-five treated over 4.7±2.1 years in the Spine Study Group database analyzed actual practice compare it results. All had at least 2 treatment. Results In survey, there was...
In Brief Study Design. A retrospective matched cohort study with control group. Objective. To compare the infection rate after posterior spinal fusion unit rod instrumentation or without gentamicin-impregnated allograft bone in children cerebral palsy (CP). Summary of Background Data. Previous studies evaluating wound rates surgery CP report an 8.7% to 10% rate. The concept using antibiotic-loaded graft (AbBGF) provide local antibiotics has been explored high risk patients, such as those...
Infection is a serious complication of surgery to correct scoliosis in patients with cerebral palsy (CP). We obtained multicenter representative figures for deep and superficial infection rates, analyzed risk factors treatment outcomes, compared deformity correction relative infection. retrospectively reviewed 157 who had posterior spinal fusion CP at one eight centers. Preoperative intraoperative variables were subjected multivariate analysis determine predictive There 16 wound infections...
The aim of this study was to investigate and evaluate complications intrathecal baclofen (ITB) pump implantation maintenance in children with cerebral palsy.We reviewed our entire consecutive series pediatric patients treated ITB between 1997 2006 at hospital. There were 174 a diagnosis palsy, 8 mixed dystonia, 2 athetosis, 3 pure dystonia. During follow-up, deaths occurred no evidence or catheter malfunction any way contributing the cause death. Acute infection within 60 days surgery late...
Retrospective case series.This study aimed to validate the Sanders Skeletal Maturity Staging System and assess its correlation curve progression in idiopathic scoliosis.The has been used predict scoliosis. This intended that initial with a larger sample size.We retrospectively reviewed 1100 consecutive patients scoliosis between 2005 2011. Girls aged 8 14 years (<2 yr postmenarche) boys 10 16 who had obtained at least 1 hand spine radiograph on same day for evaluation of skeletal age...
In Brief Study Design. Therapeutic comparative study. Objective. To evaluate the safety and efficacy of antifibrinolytic (AF) agents in reducing blood loss transfusions during posterior spinal fusion (PSF) children with cerebral palsy (CP) scoliosis. Summary Background Data. Scoliosis surgery CP is associated substantial loss. Few reports on role AFs exist. Methods. A multicenter, retrospective review a prospectively collected database 84 consecutively enrolled patients CF (age < 18 years)...
Definitive "final" surgical fusion is the common end point for growing-rod treatment of early-onset scoliosis. However, final may be unnecessary patients who have reached skeletal maturity with good alignment. This study characterizes completed but did not undergo fusion.Using a multicenter early-onset-scoliosis database, we identified 167 received from 1995 through 2010, maturity, and had minimum 2-year follow-up after their last surgery. Thirty (observation group) were compared clinically...
Background: Appearance concerns in individuals with adolescent idiopathic scoliosis can result impairment daily functioning, or body image disturbance. The Body Image Disturbance Questionnaire (BIDQ) is a self-reported, seven-question instrument that measures disturbance general populations; no studies have specifically examined those scoliosis. This study aimed to validate modified version of the BIDQ population and establish discriminant validity by comparing responses operatively...
In Brief Study Design. Multicenter, retrospective study. Objective. To compare the outcomes of three surgical treatments for congenital spinal deformity due to a hemivertebra. Summary Background Data. Congenital anomalies spine can cause significant and progressive scoliosis kyphosis. Their management may be challenging controversy remains over “best” treatment. Methods. A multicenter study patients with 1 or 2 level hemivertebra(e) was performed. The included hemiepiphysiodesis in situ...
A cross-sectional study.The purpose of this study was to assess intervertebral segmental and cumulative motion in the distal unfused segments spine patients with adolescent idiopathic scoliosis after instrumentation as a function lowest instrumented level.The implications hyper- or hypomobility are poorly understood. There is little research on changes functional movement capabilities thoracolumbar spinal fusion.Patients were prospectively offered inclusion into institutional review...