A5071306772- SARS-CoV-2 and COVID-19 Research
- COVID-19 epidemiological studies
- Viral Infections and Outbreaks Research
- COVID-19 diagnosis using AI
- Disaster Response and Management
- COVID-19 Clinical Research Studies
- SARS-CoV-2 detection and testing
- Hepatitis B Virus Studies
- Viral Infections and Vectors
- Viral gastroenteritis research and epidemiology
- Animal Virus Infections Studies
- HIV-related health complications and treatments
- Respiratory viral infections research
- COVID-19 Pandemic Impacts
- Disaster Management and Resilience
- Curcumin's Biomedical Applications
- Flood Risk Assessment and Management
- Data-Driven Disease Surveillance
- Bacteriophages and microbial interactions
- Ethics in Clinical Research
- Computational Drug Discovery Methods
- Genital Health and Disease
- Cervical Cancer and HPV Research
- Vibrio bacteria research studies
- Diabetes Management and Research
Nigerian Institute of Medical Research
2011-2024
University of the Free State
2023
First Technical University
2023
Food and Agriculture Organization of the United Nations
2023
Federal University of Agriculture
2023
University of Lagos
2020
Background: Access to diagnostics was a significant challenge during the early stages of COVID-19 pandemic, as laboratory reagents, supplies, and consumables were in short supply high demand. Central laboratories, equipped with advanced real-time PCR equipment highly skilled staff, worked long hours produce test results for travellers, hospital patients, general public. We developed SARS-CoV-2 molecular diagnostic assay suitable point-of-care testing address this challenge. Methods:...
In an outbreak, effective detection of the aetiological agent(s) involved using molecular techniques is key to efficient diagnosis, early prevention and management spread. However, sequencing necessary for mutation monitoring tracking clusters transmission, development diagnostics vaccines drug development. Many methods are fast evolving reduce test turn-around-time increase through-put compared Sanger method; however, remains gold standard clinical research with its 99.99% accuracy This...
A key element in containing the spread of SARS-CoV-2 infection is quality diagnostics which affected by several factors. We now report comparative performance five real-time diagnostic assays. Nasopharyngeal swab samples were obtained from persons seeking a diagnosis for Lagos, Nigeria. The comparison was performed on same negative, low, and high-positive sample set, with viral RNA extracted using Qiagen Viral Kit. All assays are one-step reverse transcriptase PCR Testing done according to...
A common complication of any respiratory disease by a virus could be secondary bacterial infection, which is known to cause an increase in severity. It is, however, not clear whether the presence some opportunistic pathogens called pathobionts contributes severity disease. In COVID-19 patients, undetected co-infections may associated with Therefore, we investigated implications cases.This cross-sectional study that involved archived specimens collected from nasopharyngeal samples 150 people...
Issues: Quality-management systems (QMS) are uncommon in clinical laboratories Nigeria, and until recently, none of the nation’s 5 349 have been able to attain certifications necessary begin process attaining international accreditation. Nigeria’s Human Virology Laboratory (HVL), however, began implementation a QMS 2006, 2008 it was determined that laboratory conformed requirements ISO 9001:2000 (now 2008), making first diagnostic be certified Nigeria. The HVL has now applied for World...
Lassa virus (LASV), the causative agent of fever (LF), an endemic acute viral haemorrhagic illness in Nigeria, is transmitted by direct contact with rodent, contaminated food or household items. Person-to-person transmission also occurs and sexual has been reported. Thus, this study investigated presence LASV body fluids suspected confirmed cases.this was a cross-sectional between March 2018 April 2019 involving 112 consenting post ribavirin cases attending treatment center Ondo State. Whole...
Rampant chloroquine/hydroxychloroquine poisoning in Nigerian hospitals following suggestions of its possible efficacy the treatment and prevention newly emerged COVID-19 disease informed this survey.The aim study was to assess knowledge, attitude perception populace on use chloroquine pandemic.This cross-sectional done by administering an electronic questionnaire created using Google Docs, through social media cascade methods including WhatsApp application software capture data between April...
effective and safe means of sample collection is a crucial component testing for Covid-19. Uptake key to containing controlling the spread virus. Scientists have been working on various strategies that will increase uptake COVID-19. One such method involves use drive-through sampling strategy.data was collected by both qualitative quantitative methods. An eligibility form filled online. While in-depth interviews were conducted aspect study.2,600 visits recorded at website, 2300 (88.46%)...
Malaria and COVID-19, though caused by different organisms, share a significant number of symptoms like fever, headaches, difficulty in breathing fatigue. Therefore, determining if patient is positive for COVID-19 or based on alone, might be misleading, especially during pandemic response. It has been reported that an individual begins to manifest between 10 - 15 days after infection with malaria parasite, although some individuals may asymptomatic. Some infected patients, Malaria, are also...
Introduction: Cervical cancer remains a major cause of morbidity and mortality among the female population in sub-Saharan Africa. Vaccination against human papillomavirus (HPV), main causative agent, has potential to eradicate cervical cancer. In-country evidence sub-types HPV associated with is scanty, thus necessitating this study. Methods: A cross-sectional study was performed using multistage sampling technique. molecular technique Cobas 4800 machine used for genotyping. Results: 570...
The COVID-19 virus is rapidly crossing borders and spreading across countries the globe, with 212 currently affected as of May 2020, 6 months since reports first case in November 2019 Wuhan, China.Global efforts to lessen impact pandemic span surveillance, preparedness, response, prevention, testing, contact tracing, treatment.Co-creation Hub (CcHUB) collaboration Nigerian Institute Medical Research (NIMR) LifeBank developed a digital system support process free testing suspected cases...
Background: The world is currently experiencing a healthcare crisis caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Healthcare workers (HCWs) are at the forefront of controlling spread disease; this response has resulted in huge number infections amongst HCWs and unfortunately some casualties. Infection prevention control practices (IPC) practical, proven methods that prevent avoidable harm to patients protect health from contagious infection. This study was done...
Abstract Population-based study is known to be a very essential type of during and after pandemic or epidemic, as it provides crucial information on the incidence, prevalence, risk factors disease in question. There has been limited about challenges faced conducting such surveys Nigeria. In this paper, we will share our experience, describe population-based seroepidemiological COVID–19 Lagos, Some were peculiar specific Local Government Areas (LGAs) while others general. The include general...
Objectives: The objective of this study was to assess the factors affecting testing behaviours amongst population in Ondo and Lagos States. Methods: A cross-sectional involving 704 individuals who were considered eligible for COVID-19 4 local governments (307) (397) states Nigeria, conducted from April-June 2021. Respondents selected using simple random sampling. close-ended questionnaire administered a digital survey platform known as SurveyCTO. Data analyzed R 4.1.0. Results: In state,...
The Ceylon Journal of Science is a peer-reviewed journal published quarterly by the University Peradeniya, Sri Lanka in March, June, September and December. It aimed at publishing high quality research articles on topics related to different disciplines Science. accepts original articles, book reviews, reviews mini-reviews, short communications, opinions, notes, commentaries notes. has its own website https://site.pdn.ac.lk/cjs/. strictly adheres publication ethics as emphasized Committee...
The availability and ease of accessibility highly active antiretroviral therapy have changed the horizon Human Immunodeficiency Virus (HIV) pandemic from a fatal illness to chronic lifelong disease. People living with HIV (PLWH) are longer, as such there is an increasing risk acquiring diseases non-communicable A cross-sectional study among adolescents young adults (AYLHIV) attending clinic Nigerian Institute Medical Research. Anthropometric measurements (weight, height, waist circumference,...
Lassa Fever (LF) continues to be an endemic acute viral hemorrhagic fever (VHF) illness in Nigeria. Many suspected cases of LF infection have subsequently been confirmed negative and raises concerns as what the diagnosis such patients could be. Hence this study was determine causative agents unconfirmed among initially South Western In retrospective study, blood samples originally collected from 233 a outbreak response at Owo Ose LGAs Ondo State, were transported triple level packaging...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and Plasmodium species are the causative agents of disease 2019 (COVID-19) malaria respectively with similar clinical presentations. The objective this study is to determine burden co-infection SARS-CoV-2 in general population. Five (5 mLs) blood samples were collected for parasite test. test was performed using a commercially available one-step antigen falciparum histidine-rich protein (Pf HRP-II) rapid kit. results showed that...
<title>Abstract</title> Background Video Observed Therapy (VOT) is a method of adherence monitoring where participants transmit digital images their treatment intake to central location for review; either synchronously or asynchronously. VOT presents an option that can be explored developing countries like Nigeria with high TB burden, thereby reducing the burden and ultimately eliminating it. Methods The study was two-arm individually randomised clinical trial conducted by Institute Medical...
<title>Abstract</title> Background Disaster preparedness is critical for households, businesses, and communities. Over the years, Nigerians have had to rely on sheer luck providence save themselves from disasters with little or no help coming rescue agencies which many occasions been found lack capacity wherewithal intervene in such difficult moments. This research was focused determining level of awareness, response humanitarian concerning flood Nigeria. a descriptive cross-sectional study...
Access to essential diagnostics is crucial for primary healthcare (PHC) in low-and-middle income countries (LMICs). Many LMICs have invested equipping PHC with point-of-care (PoC) infectious diseases, however there has been no similar investment improve capacities clinical chemistry. The biochemistry gap among the deterrents universal health coverage. A social sciences project was conducted aim understand key stakeholders' insights on pertinence of PoC LMICs. Data generation between...
Abstract Aim Porcine circovirus 2 (PCV2) is a swine viral pathogen of substantial economic importance in pig farming globally. However, large-scale surveillance needed to determine its prevalence and associated risk factors Nigerian pigs. We conducted molecular-based mapping PCV2 the southwest, Nigeria, spatiality. Methods results A total 648 individual faecal samples were collected from different age groups pigs 67 farms three southwest states. The polymerase chain reaction technique was...