A5077564635- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Peripheral Artery Disease Management
- Cardiac Imaging and Diagnostics
- Cerebrovascular and Carotid Artery Diseases
- Diagnosis and Treatment of Venous Diseases
- Venous Thromboembolism Diagnosis and Management
- Cardiac pacing and defibrillation studies
- Health Systems, Economic Evaluations, Quality of Life
- Acute Myocardial Infarction Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Neurological Disease Mechanisms and Treatments
- Acute Ischemic Stroke Management
- Traditional Chinese Medicine Analysis
- Diet and metabolism studies
- Chronic Disease Management Strategies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Lipoproteins and Cardiovascular Health
- Streptococcal Infections and Treatments
- Cardiac Health and Mental Health
- Infective Endocarditis Diagnosis and Management
- Vitamin K Research Studies
- Flavonoids in Medical Research
- Otolaryngology and Infectious Diseases
Sana Klinikum Lichtenberg
2019-2024
Zhengzhou People's Hospital
2015-2024
Invictus Medical (United States)
2024
Tianjin University of Traditional Chinese Medicine
2013
Tongji University
2006-2007
Background The aim of the present study was to prospectively evaluate sensitivity, specificity, positive and negative likelihood ratios (LR+, LR-) ankle - brachial index (ABI), using conventional digital subtraction angiography (DSA) as reference standard, in assessment lower extremity arteries, research threshold value ABI diagnosing periphery arterial disease (PAD), well relationship between stenosis artery Chinese high-risk cardiovascular patients. Methods Results A total 298 consecutive...
Peripheral arterial disease (PAD) is an important manifestation of systemic atherosclerosis and associated with elevated cardiovascular morbidity mortality. The aim the present study was to evaluate use antiplatelet agents, statins angiotensin-converting enzyme inhibitors (ACEI) in Chinese high-risk (CV) patients PAD, emphasis on need for aggressive medical management all atherosclerotic manifestations.Medical records from 5,263 at high risk CV were evaluated ACEI without PAD. PAD defined as...
Female patients affected by non-valvular atrial fibrillation (NVAF) have a higher risk of stroke compared with male patients. Left appendage (LAA) closure has been demonstrated as reasonable alternative to warfarin therapy for prevention in NVAF. However, the impact sex-related differences on outcomes undergoing LAA (LAAC) remains unclear. Our study investigated LAAC efficacy and safety endpoints between sexes. 387 consecutive WATCHMAN device implantation were enrolled stratified sex....
Objective The effect of atrial fibrillation (AF) patterns on outcomes remains controversial. This study aims to evaluate the influence AF type risk cardiocerebrovascular events after left appendage closure (LAAC) at long-term follow-up. Methods was categorized as paroxysmal (PAF) and non-PAF (NPAF). baseline characteristics, procedural data, peri-procedural complications, between patients with PAF NPAF LAAC were compared. Results We analyzed 410 (mean age 74.8 ± 8.2 years; 271 male; 144 PAF,...
Many clinical trials showed that antiatherosclerotic drugs could significantly reduce the mortality in patients with peripheral arterial disease (PAD). The aim of this study was to evaluate effect statins, calcium channel blockers (CCBs), angiotensin-converting enzyme inhibitors (ACEIs), angiotensin receptor (ARBs), antiplatelet drugs, beta-blockers, diuretics, and hypoglycemic hospitalized Chinese PAD. Nine hundred fifty-eight (mean age 72.35 ± 9.39 years, 472 male) PAD were continuously...
Introduction: Patients with non-valvular atrial fibrillation (NVAF) and previous stroke are at significantly higher risk of recurrence. Data on the efficacy left appendage closure (LAAC) these patients is limited. The aim this study was to investigate differences LAAC long-term cardio- cerebrovascular outcomes in NVAF vs. without prior stroke. Methods: Three hundred seventy consecutive who underwent were enrolled divided into non-stroke groups based history Endpoints, such as...
Higher CHA2DS2-VASc score is associated with an increased risk of adverse cardio-cerebrovascular events in patients non-valvular atrial fibrillation (NVAF), regardless oral anticoagulation (OAC) status. However, whether this association still exists undergoing left appendage closure (LAAC) unknown. We evaluated the impact on LAAC efficacy and outcomes.A total 401 consecutive were included divided into 3 groups based (0-2, 3-4, ≥5). Baseline characteristics, periprocedural complications,...
To evaluate the influence of congestive heart failure (CHF) on safety and efficacy left atrial appendage closure (LAAC) in non-valvular fibrillation (NVAF) patients.A total 401 patients who consecutively underwent LAAC with Watchman LAmbre devices were divided into CHF (85 cases) non-CHF (316 groups. Comparisons between groups performed against data.No significant differences found implantation success periprocedural complication rates two During a mean 2.2 years follow-up, incidence rate...
To investigate safety and effectiveness of left atrial appendage closure (LAAC) in fibrillation patients with prior major bleeding.A total 377 consecutive scheduled for LAAC Watchman device were divided into bleeding group (n = 137) non-bleeding 240). Data compared between groups.The had more ≥75 years old (P 0.044), higher CHA2DS2-VASc 0.029) HAS-BLED scores 0.001) than the group. During long-term follow-up, except thromboembolism event 0.031), incidences , all-cause death co-primary...
心房颤动(房颤)的最大危害是引起卒中或血栓栓塞事件，临床上常以抗凝药物，包括华法林或新型口服抗凝药物来有效降低血栓栓塞事件，但药物治疗有增加出血的风险。基于非瓣膜性房颤患者90%的血栓是来自左心耳，近年有些临床研究显示，左心耳封堵术(LAAC)可用于卒中风险高危、不能耐受华法林治疗或不愿长期口服抗凝药物的房颤患者的治疗，不仅能减少卒中、体循环栓塞与心血管死亡复合事件，而且在降低心血管死亡与全因死亡事件方面较口服华法林有更优的结局。但LAAC的远期预后、与新型口服抗凝药物的比较以及在国人房颤患者的应用经验仍需进一步研究。
Abstract Purpose: Left atrial appendage closure (LAAC) may present an alternative to anticoagulation in patients with non-valvular fibrillation (NVAF). However, evidence regarding benefit of LAAC prior major bleeding is limited. We evaluate whether a previous factor influences the safety and effectiveness LAAC. Methods: A total 377 consecutive scheduled for were categorized into group (n=137) non-bleeding (n=240). The implantation success prevalence severe peri-procedural complications,...