AIM: To describe the anatomic characteristics of lacrimal sac and its adjacent bone structures to provide surgical recommendations for endoscopic dacryocystorhinostomy (EN-DCR). METHODS: This retrospective comparative study involved 118 sides with complete nasolacrimal duct obstruction 83 unaffected from 126 patients. Computed tomographic-dacryocystography (CT-DCG) scans were performed before surgery, image reconstruction was used obtain continuous 0.75-mm axial, coronal, segmental sections...

Aim The aim of this study was to evaluate the long-term visual outcomes and factors affecting results in children undergoing secondary intraocular lens (IOL) implantation following primary congenital cataract extraction. Methods Children with cataracts who underwent IOL for aphakia at Eye ENT Hospital Fudan University between January 1, 2001, December 31, 2007, were retrospectively reviewed. One eye randomly selected bilateral cataracts. Laterality, type (total or partial opacity), sex, age...

Purpose To investigate the influence of lens thickness (LT) on accuracy Kane, Hill-RBF 3.0 Barrett Universal II (BUII), Emmetropia Verifying Optical (EVO), and Pearl-DGS formulas in eyes with different axial lengths (AL).

Abstract Background The 24-item Recovery Assessment Scale (RAS) is the most widely-used and well-validated tool for measuring recovery people with mental illness. current study aims to assess reliability validity of an 8-item short form RAS (RAS-8) among a Chinese sample living schizophrenia. Methods A 400 schizophrenia were recruited scale validation. Internal consistency was tested by calculating Cronbach's α. Test–retest calculated using intraclass correlation coefficient (ICC) total...

Objective. To evaluate the postoperative visual quality of cataract patients with extreme myopia after implantation aspheric intraocular lenses (IOLs). Methods. Thirty-three eyes were enrolled in this prospectivestudy. Eighteen an axial length longer than 28 mm included group, and other 15 nonextreme group. Phacoemulsification IOL performed. Six months surgery, best-corrected acuity (BCVA), contrast sensitivity, wavefront aberrations measured, subjective was assessed. Results. The BCVA...

Purpose: To evaluate whether α-lipoic acid (LA) inhibits lens opacity of naphthalene-induced cataract by altering post-translational modifications (PTMs) and protecting the chaperone activity α-crystallins.Methods: Forty-five Sprague-Dawley rats were divided into three groups: control, naphthalene, naphthalene plus LA. Cataracts induced oral administration 1 g naphthalene/kg body weight/day. Rats in LA group also fed 30 mg LA/day. The development naphthalene-initiated was monitored every...

To determine the appropriate concentration of trypan blue (TB) for subretinal injection in a rat model and to provide safety profile that limits retinal toxicity while maintaining dye visibility.Adult rats were subretinally injected with various concentrations either TB or phosphate-buffered saline (PBS); which received sham injections served as an additional control. The areas visualized under surgical microscope. Electroretinography (ERG) was performed measure function. Animals then...

Despite significant advances in cataract surgery techniques, posterior capsule opacification (PCO) remains a common complication. In PCO, remaining epithelial cells cloud the lens and impair postoperative vision. This vitro study was designed to investigate potential of gene-based approach, specifically over-expression proapoptotic BAX gene, prevent PCO. Human (HLECs) were transfected by nucleofection with plasmid encoding fusion protein green fluorescent human BAX. The expression levels its...

Abstract Purpose To describe the anatomic characteristics of lacrimal sac and its adjacent bone structures to provide surgical recommendations for endoscopic dacryocystorhinostomy (EN - DCR) in Asians. Methods This retrospective comparative study involved 118 sides with complete nasolacrimal duct obstruction 83 unaffected sides. Computed tomographic dacryocystography (CT-DCG) scans were performed before surgery, image reconstruction was used obtain continuous 0.75-mm axial, coronal,...

Background: Myocardial infarction with nonobstructive coronary artery disease (MINOCA) is a special syndrome clear evidence of myocardial ischemia, but no stenosis imaging sign. Inflammation closely related to the prognosis such diseases. This study focuses on correlation between cumulative exposure inflammation during hospital stay period and MINOCA patients. Methods: was single-center, prospective cohort study. Patients who underwent angiography diagnosed in Fuwai Hospital from January...

According to the latest official report, incidence and mortality rates of cardiovascular diseases continue rise in China.1 Among these, coronary heart disease (CHD) represents most significant threat public health imposes substantial social burdens. Percutaneous intervention (PCI) has rapidly advanced as a key treatment modality for CHD. With an aging population, number PCIs performed China is projected increase over long term. To enhance prognosis patients with CHD, it essential improve...

Purpose. To evaluate and compare the objective subjective visual function after implantation of 2 aspheric intraocular lenses (IOLs) in Chinese cataract patients. Methods. Forty-one eyes 28 patients with were randomly assigned to receive either MC X11 ASP IOL or AcrySof IQ IOL. Three months postoperatively, best-corrected acuity (BCVA), contrast sensitivity, wavefront aberrations, quality measured. The degree posterior capsule opacification (PCO) was recorded at last follow-up. Results....

Objective To investigate whether apeptosis of human lens epithelial cells (HLEC) can be induced by inhibition bcl-2 shRNA. Methods It was an experimental study. Two pairs oligonucleotides were synthesized and inserted into plasmid PGCsi to generate shRNA eukaryotic expression vectors, named P1 P2. At 48 hours after transfection in HLEC (SRA01/04) with LipofectamineTM 2000, the whole cell protein extracted detected Western blot. The mRNA level real-time PCR percentage HLECs undergoing...

An 8-year-old boy presented with low vision in his left eye and no right since birth. The diagnosis was bilateral microphthalmos orbital cysts a dense cataract the eye. To improve eye, extraction anterior vitrectomy were performed. After surgery, visual acuity improved from light perception to counting fingers. During follow-up of 3 months, severe complications occurred. our knowledge, this is first case surgery cysts. Neither author has financial or proprietary interest any material method...

Objective To explore the distribution characteristics of intra/extracranial large-artery disturbance in patients with ischemic stroke (IS)/transient attack (TIA). Methods The medical history information 169 IS/TIA was recorded. The results laboratory examination, electrocardiogram, echocardiography, abdominal ultrasound and chest radiography were analyzed. At same time, intra/extra-cranial large arteries examined to analyze degree, pattern their disturbance. Results Among them,...