- Nutrition, Health and Food Behavior
- Thin-Film Transistor Technologies
- Food Quality and Safety Studies
- Ginseng Biological Effects and Applications
- Diet and metabolism studies
- Nutritional Studies and Diet
- Fungal Biology and Applications
- Plant Molecular Biology Research
- Transition Metal Oxide Nanomaterials
- Plant tissue culture and regeneration
- Nuclear Materials and Properties
- Pharmacological Effects of Natural Compounds
- High Temperature Alloys and Creep
- High-Temperature Coating Behaviors
- Organic Light-Emitting Diodes Research
- Herbal Medicine Research Studies
- Health and Wellbeing Research
- Gastrointestinal motility and disorders
- Metabolism, Diabetes, and Cancer
- ZnO doping and properties
- Advanced Memory and Neural Computing
- Gut microbiota and health
- Diet, Metabolism, and Disease
- Phytoestrogen effects and research
- Drug-Induced Hepatotoxicity and Protection
Jeonbuk National University
2013-2025
Chonbuk National University Hospital
2015-2025
Yonsei University
2004-2025
Kyung Hee University
2016-2023
Ajou University
2023
Severance Hospital
2023
Yonsei University College of Dentistry
2015-2021
Rural Development Administration
2013-2019
Hanyang University
2019
Korea University
2006-2018
Very-long-chain fatty acids (VLCFAs) are essential precursors of cuticular waxes and aliphatic suberins in roots. The first committed step VLCFA biosynthesis is condensation C(2) units to an acyl CoA by 3-ketoacyl synthase (KCS). In this study, two KCS genes, KCS20 KCS2/DAISY, that showed higher expression stem epidermal peels than stems were isolated. relative KCS2/DAISY transcripts was compared among various Arabidopsis organs or tissues under stress conditions, including osmotic stress....
Early intervention using dietary supplements may be effective in alleviating cognitive impairment among individuals with mild (MCI). This study investigated the efficacy and safety of Lactobacillus plantarum C29-fermented soybean (DW2009) as a nutritional supplement for enhancement. One hundred MCI were randomly assigned to take DW2009 (800 mg/day, n = 50) or placebo 12 weeks. The primary outcome measure was change composite score functions related memory attention, measured by computerized...
Endothelial dysfunction is one of the main age-related arterial phenotypes responsible for cardiovascular disease (CVD) in older adults. This endothelial results from decreased bioavailability nitric oxide (NO) arising downstream oxidative stress. In this study, we investigated protective effect anthocyanins and underlying mechanism rat thoracic aorta human vascular cells aging models. vitro, cyanidin-3-rutinoside (C-3-R) cyanidin-3-glucoside (C-3-G) inhibited d-galactose (d-gal)-induced...
Summary The synthesis of fatty acids and glycerolipids in wild‐type Arabidopsis leaves does not typically lead to strong triacylglycerol ( TAG ) accumulation. LEAFY COTYLEDON 2 LEC 2) is a master regulator seed maturation oil accumulation seeds. Constitutive ectopic expression causes somatic embryogenesis defects seedling growth. Here, we report that senescence‐inducible caused threefold increase levels transgenic compared with the plants. Plant growth was severely affected by response...
Increased central arterial stiffness is an emerging risk factor for cardiovascular disease. Acute aerobic exercise reduces stiffness, while acute resistance may increase but this not a universal finding. We tested whether program was associated with in healthy young men.Thirteen subjects were studied under parallel experimental conditions on 2 separate days. The order of experiments randomized between (8 exercises at 60% 1 repeated maximal) and sham control (seated rest the room)....
The prevalence of metabolic syndrome, hypertension, and diabetes has been increasing rapidly in Korea. rate increase paralleled the replacement Korean traditional diets (KTD), which emphasize vegetables fermented foods, with western style dietary patterns that are rich animal foods saturated fat. We aimed to investigate efficacy KTD controlling fasting plasma glucose, blood pressure, cardiovascular disease risk factors hypertensive type 2 diabetic (T2D) patients. Forty-one patients (61.8±1.5...
The LEAFY COTYLEDON2 ( LEC2 ) gene plays critically important regulatory roles during both early and late embryonic development. Here, we report the identification of from castor bean plant Ricinus communis ), characterize effects its overexpression on regulation lipid metabolism in transgenic Arabidopsis plants. exists as a single‐copy bean, is expressed predominantly embryos, encodes protein with conserved B3 domain, but different N‐ C‐terminal domains to those found Arabidopsis. Ectopic...
Health benefits of Kochujang (KCJ) and its bioactive compounds have been reported in several vitro animal studies.The aim this study was to investigate the efficacy KCJ supplementation on body composition blood lipid profiles overweight adults.Sixty men women with BMI ≥23 kg/m2 waist-hip-ratio (WHR) ≥0.90 for ≥0.85 were randomly assigned a supplement (n=30, 32 g/day) or placebo group 12-week, double-blind, controlled study. We measured anthropometric parameters, serum profiles, abdominal fat...
Floral transition is influenced by environmental factors such as light and temperature. Plants are capable of integrating photoperiod ambient temperature signaling into their developmental program. Despite extensive investigations on individual genetic pathways, little known about the molecular components that integrate both pathways. Here, we demonstrate RING finger-containing E3 ubiquitin ligase CONSTITUTIVE PHOTOMORPHOGENIC1 (COP1) acts an integrator signaling. In addition to role in...
The prevalence of metabolic diseases has risen globally in parallel with the obesity epidemic over past few decades. Green tea been reported to have metabolically beneficial effects on obesity; however, mechanism by which green regulates lipid metabolism is not clearly understood. Male c57BL/6 mice were fed a normal chow diet, high-fat diet (HFD), or an HFD supplemented various doses epigallocatechin gallate-rich extract (GTE) for 12 weeks. GTE supplementation reduced body weight gain,...
Background: Cardiorespiratory fitness (CRF) is a fundamental component of physical fitness.While maximal oxygen uptake (VO2max) the gold standard for quantifying CRF, exercise tests using direct measurements VO2max are dependent on availability laboratory equipment, and thereby expensive time consuming.Recently, an equation was formulated to indirectly estimate YMCA 3-minute step test.Methods: The study included 15 Korean (KR) Vietnamese (VN) healthy adults aged 19-35 years.All subjects...
A recent animal study demonstrated that administration of Lactobacillus plantarum HAC01 isolated from Korean kimchi improved glycemic control in type 2 diabetic mice. In the present study, we evaluated HAC01's effects on metabolic parameters prediabetic human subjects. Forty subjects with impaired glucose tolerance were randomly assigned to receive a daily placebo (n = 20) or dose over eight weeks. The primary endpoint was change h postprandial (2h-PPG) levels and secondary endpoints...
Fermented foods are loved and enjoyed worldwide part of a tradition in several regions the world. Koreans have traditionally had healthy diet since people this region followed fermented-foods for at least 5000 years. Fermented-product footprints evolving beyond boundaries taking lead world food. foods, such as jang (fermented soybean products), kimchi vegetables), jeotgal fish), vinegar (liquor with grain fruit fermentation), prominent fermented Korean culture. These four major been passed...
Various forms of fermented soybean products are well documented for their health benefits. The efficacy anti-obesogenic effect Doenjang, one the most commonly used seasonings in Korean cuisine, has been reported only animal models; thus, an evaluation Doenjang needs to be conducted human studies. We aimed test hypothesis that supplementation reduces body weight and changes composition overweight adults. A total 51 adults participated this study. group males with BMI ≥ 23 kg/m(2) waist hip...
Wound healing is an important issue that influences quality of life, and the need for products associated with wound growing annually. New materials therapies skin wounds are being continuously researched developed in order to increase treatment efficacy. Here, we show peptide AES16-2M comprised five short amino acid sequences (REGRT) demonstrates efficacy healing. exerted more effective than control acute model, tissue regeneration was similar normal AES16-2M-treated skin. We found...
Excessive alcohol consumption is one of the most significant causes morbidity and mortality worldwide. Alcohol oxidized to toxic carcinogenic acetaldehyde by dehydrogenase (ADH) further a non-toxic acetate aldehyde (ALDH). There are two major ALDH isoforms, cytosolic mitochondrial, encoded ALDH1 ALDH2 genes, respectively. The polymorphism associated with flushing response use. Emerging evidence shows that Lactobacillus Bifidobacterium species encode (ALDH) mediate metabolism, A randomized,...
Cordyceps is a traditional Chinese herb that produces various biopharmaceutical effects, including immune-enhancing effects. In this study, we prepared mycelium culture extract (Paecilomyces hepiali, CBG-CS-2) to confirm its efficacy in enhancing the immune system and evaluate safety healthy adults. Healthy adults were divided into intervention group (n = 39), who given 1.68 g/day of CBG-CS-2 capsules, control 40) for 8 weeks. The activities natural killer (NK) cells serum levels...