- Retinal Diseases and Treatments
- Multilevel Inverters and Converters
- Neurological Disease Mechanisms and Treatments
- Sensorless Control of Electric Motors
- Food Quality and Safety Studies
- GABA and Rice Research
- Advanced Glycation End Products research
- Glaucoma and retinal disorders
- Diabetes Treatment and Management
- Teleoperation and Haptic Systems
- Iterative Learning Control Systems
- Ginger and Zingiberaceae research
- Sirtuins and Resveratrol in Medicine
- Microgrid Control and Optimization
- Ginseng Biological Effects and Applications
- Pharmacological Effects of Natural Compounds
- Seaweed-derived Bioactive Compounds
- Electric Motor Design and Analysis
- Chronic Kidney Disease and Diabetes
- Trace Elements in Health
- Nutrition, Health and Food Behavior
- Biochemical effects in animals
- Ginkgo biloba and Cashew Applications
- Pharmacology and Obesity Treatment
- Garlic and Onion Studies
Seoul National University
2013-2025
Chonbuk National University Hospital
2014-2023
Jeonbuk National University
2014-2023
Jeonbuk Development Institute
2011-2015
LG (South Korea)
2015
Doosan (South Korea)
2014
This paper presents a nine-phase permanent-magnet synchronous motor (PMSM) drive system based on multiple three-phase voltage source inverters. The PMSM was developed as traction for an ultrahigh-speed elevator. mathematical model of the simplified through symmetry system. Using model, can be controlled by well-known d-q control theory. feasibility and validity were experimentally demonstrated at world's tallest elevator test tower. Moreover, additional experiment performed to ensure...
Endothelial dysfunction is one of the main age-related arterial phenotypes responsible for cardiovascular disease (CVD) in older adults. This endothelial results from decreased bioavailability nitric oxide (NO) arising downstream oxidative stress. In this study, we investigated protective effect anthocyanins and underlying mechanism rat thoracic aorta human vascular cells aging models. vitro, cyanidin-3-rutinoside (C-3-R) cyanidin-3-glucoside (C-3-G) inhibited d-galactose (d-gal)-induced...
We report proteogenomic analysis of locally advanced cervical cancer (LACC). Exome-seq data revealed predominant alterations keratinization-TP53 regulation and O-glycosylation-TP53 axes in squamous adeno-LACC, respectively, compared to early-stage cancer. Integrated clustering mRNA, protein, phosphorylation identified six subtypes (Sub1-6) LACC among which Sub3, 5, 6 showed the treatment-resistant nature with poor local recurrence-free survival. Elevated immune extracellular matrix (ECM)...
Background: Cardiorespiratory fitness (CRF) is a fundamental component of physical fitness.While maximal oxygen uptake (VO2max) the gold standard for quantifying CRF, exercise tests using direct measurements VO2max are dependent on availability laboratory equipment, and thereby expensive time consuming.Recently, an equation was formulated to indirectly estimate YMCA 3-minute step test.Methods: The study included 15 Korean (KR) Vietnamese (VN) healthy adults aged 19-35 years.All subjects...
Cordyceps is a traditional Chinese herb that produces various biopharmaceutical effects, including immune-enhancing effects. In this study, we prepared mycelium culture extract (Paecilomyces hepiali, CBG-CS-2) to confirm its efficacy in enhancing the immune system and evaluate safety healthy adults. Healthy adults were divided into intervention group (n = 39), who given 1.68 g/day of CBG-CS-2 capsules, control 40) for 8 weeks. The activities natural killer (NK) cells serum levels...
Augmenting glucose utilization in skeletal muscle via the phosphatidylinositol-3 kinase (PI3 kinase)/protein B (Akt) pathway or adenosine monophosphate (AMP)-activated protein (AMPK) is necessary to regulate hyperglycemia patients with type 2 diabetes mellitus.We investigated effect of mulberry leaf extract (MLE) on uptake cells and explored its vivo antidiabetic potential.Male db/db mice were treated either MLE (50 mg/kg, 100 250 mg/kg) metformin (100 for 8 weeks.MLE treatment stimulated...
Swelling of retinal Müller cells is implicated in edema and neuronal degeneration. cell swelling observed patients with liver failure referred to as hepatic retinopathy. In the present study, we evaluated effects aloin, an anthraquinone-C-glycoside various Aloe species, on dysfunction a rat model thioacetamide (TAA)-induced Experimental retinopathy was induced by three injections TAA (200 mg/kg/day, intraperitoneal injection) for 3 days rats. After last injection TAA, aloin (50 100 mg/kg)...
: Menopause compounds many cardiometabolic risk factors through endogenous estrogen withdrawal. This study aimed to find the association between serum follicle-stimulating hormone (FSH) levels and in post-menopausal Korean women. A total of 608 women from eight randomized double-blind, placebo-controlled clinical trials on menopause during year 2012-2019 were analyzed. Cardiometabolic such as body mass index, waist circumference, systolic blood pressure, fasting glucose, triglycerides (TG),...
This paper presents an application of a disturbance observer for relative position control system. In this system, since the prefixed motion profile is not defined <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">ex ante</i> , acceleration state which generated based on also available. Therefore, feedforward controls cannot be used, and performance restricted solely by bandwidth controller. To enhance performance, observers can utilized actively....
Dyslipidemia is associated with endothelial dysfunction, which linked to nitric oxide (NO) biology. The coupling of NO synthase cofactors a major step for release. This study aimed investigate the vascular pharmacology effects mulberry in rat thoracic aorta and human cells. In vitro, we investigated protective extract its main component cyanidin-3-rutinoside (C-3-R), against oxidized low-density lipoprotein (ox-LDL)-induced (eNOS) uncoupling. Whereas ox-LDL significantly decreased levels...
The goal of treatment for mild cognitive impairment (MCI) is to reduce the existing clinical symptoms, delay progression and prevent Alzheimer’s disease (AD). At present, there no effective drug therapy AD treatment. However, early intake dietary supplements may be in alleviating delaying MCI. This study aims evaluate effects sesame oil cake extract (SOCE) supplementation on function aged 60 years or older adults with memory impairment. A total 70 subjects received either SOCE (n = 35)...
Aging | doi:10.18632/aging.205343. Geum-Hwa Lee, Hwa-Young Young-Je Lim, Ji-Hyun Kim, Su-Jin Jung, Eun-Soo Soo-Wan Chae, Juwon Junghyun Mohammad Mamun Ur Rashid, Kyung Hyun Min, Han-Jung Chae
Dry eye disease is affected by a broad range of causes such as age, lifestyle, environment, medication and autoimmune diseases. These induce tear instability that activates immune cells promotes expression inflammatory molecules. In this study, we investigated the therapeutic effects an ethanolic extract Aucuba japonica (AJE) its bioactive compound, aucubin, on dry disease. The human corneal were exposed to desiccation stress induced exposing air, so viability was decreased. On other hand,...
In this paper, a motion controller based on Field Programmable Gate Array (FPGA) with high performance current regulator is presented. This system contains processor and bandwidth as peripheral, all of these are implemented single-chip FPGA. The execution time the less than 200 ns at 100 MHz clock frequency. Thanks to fast execution, inevitable digital delay, which 1.5 times sampling period in PWM inverter has been reduced half period. As result, control extended up about 3 kHz 10 switching...
Advanced glycation end products (AGEs) is a causative factor of various chronic diseases, including kidney disease and atherosclerosis. AGE inhibitors, such as aminoguanidine pyridoxamine, have the therapeutic activities for reversing increase in AGEs burden. This study evaluated inhibitory effects aucubin on formation methylglyoxal (MGO)-modified vitro. We also determined potential activity reducing burden kidney, blood vessel, heart, retina exogenously MGO-injected rats. Aucubin inhibited...
The conventional motion control system simply consists of a PID position controller and disturbance observer. estimated speed from the observer has been used to as feedback force, which is byproduct observer, reject disturbance. However, in this case rejection performance should be traded off with estimation performance. This paper explains trade-off using Bode analysis presents dual for application. proposed method uses two observers, where one dedicated other compensation. enhanced by...