A5101893423- DNA Repair Mechanisms
- Genomics and Chromatin Dynamics
- Biofuel production and bioconversion
- Higher Education and Teaching Methods
- Anaerobic Digestion and Biogas Production
- Thermochemical Biomass Conversion Processes
- Medical Imaging and Analysis
- Asian Culture and Media Studies
- Composting and Vermicomposting Techniques
- Language, Metaphor, and Cognition
- Scoliosis diagnosis and treatment
- Municipal Solid Waste Management
- Memory and Neural Mechanisms
- Stress Responses and Cortisol
- Engineering Education and Curriculum Development
- Educational Reforms and Innovations
- Cancer-related molecular mechanisms research
- Spinal Fractures and Fixation Techniques
- Phosphorus and nutrient management
- Microplastics and Plastic Pollution
- Algal biology and biofuel production
- Epigenetics and DNA Methylation
- Cholinesterase and Neurodegenerative Diseases
- Neurotransmitter Receptor Influence on Behavior
- Phosphodiesterase function and regulation
Jiangsu Academy of Agricultural Sciences
2014-2025
Ministry of Agriculture and Rural Affairs
2018-2025
Xinjiang University
2025
Soochow University
2024
Beijing Institute of Petrochemical Technology
2010-2024
Knowledge Integration (United Kingdom)
2024
Nanjing Agricultural University
2023
Capital Medical University
2019-2022
National Clinical Research Center for Digestive Diseases
2020-2022
Seoul School of Integrated Sciences and Technologies
2022
Abstract Previous genome-wide association studies have identified dozens of susceptibility loci for sporadic Alzheimer’s disease, but few these been validated in longitudinal cohorts. Establishing predictive models disease based on novel variants is clinically important verifying whether they pathological functions and provide a useful tool screening risk. In the current study, we performed two-stage study 3913 patients with 7593 controls four (rs3777215, rs6859823, rs234434, rs2255835;...
The present study investigated the effects of social defeat stress on behaviours and expressions 78-kDa glucose-regulated protein (Grp78), CCAAT/enhancer-binding (C/EBP) homologous (CHOP) choline acetyltransferase (Chat) in brains adolescent mice. Adolescent male C57BL/6J mice were divided into two groups (susceptible unsusceptible) after 10 d stress. In expt 1, behavioural tests conducted processed for Western blotting day 21 2, avoidance subsequently 12 Chronic produced more pronounced...
What is the optimal protocol of management for phenotypic female patients with Y chromosome or Y-derived sequences, in particular adult patients? Immediate gonadectomy, long-term hormone therapy and psychological care are suggested to be older sequences. Phenotypic sequences at increasing risk developing gonadal tumors age. Early diagnosis safe guidelines these needed. One hundred two women were included a straightforward, retrospective-observational study conducted over period 26 years from...
Abstract Background Direct analogs of chemically modified bases that carry important epigenetic information, such as 5-methylcytosine (m5C)/5-methyldeoxycytosine (5mC), 5-hydroxymethylcytosine (hm5C)/5-hydroxymethyldeoxycytosine (5hmC), and N 6 -methyladenosine (m6A)/ -methyldeoxyadenosine (6mA), are detected in both RNA DNA, respectively. The base 4 -acetylcytosine (ac4C) is well studied RNAs, but its presence roles cellular DNA have not been explored. Results Here, we demonstrate the...
The Chinese version of Boston Naming Test (BNT-C) is administered in China widely. However, the neuropsychological parameter BNT-C native Chinese-speaking elders mainland has not been explored systematically. aim this study was to explore cultural influences on performance and establish norms among Beijing.A total 161 native, Chinese-speaking, cognitively normal aged ≥55 years were enrolled from various communities Beijing. conducted all participants. internal consistency, participants'...
Beta-propeller protein-associated neurodegeneration (BPAN) is a rare neurological disease characterized by severe cognitive and motor impairments. BPAN caused de novo pathogenic variants in the WDR45 gene on X chromosome. encodes protein WDR45/WIPI4, known regulator of autophagy. A defective autophagy has been observed cellular models associated with dysfunctions knockout (KO) mice. However, it remains unclear whether autophagic defect directly contributes to all loss-induced phenotypes or...
ABSTRACT This paper proposes a stochastic version based on deterministic SVEIRS (Susceptible‐Vaccinated‐Exposed‐Infectious‐Recovered‐Susceptible) model with saturation incidences and analyzes their dynamic properties control strategies. For the model, we simply study asymptotic of disease‐free endemic equilibria discuss parametric branching. Focusing prove existence uniqueness global positive solution. Further, extinction persistence are obtained under certain threshold conditions. By...
ABSTRACT An abrupt change occasionally occurs when the dynamical system suddenly shifts from one stable state to a new state, which can take place in many complex systems, such as climate, ecosystem, social system, and so on. In order detect change, this article presents novel method – sliding transformation parameter ( STP ) on basis of skewness Box–Cox transformation. Tests model time series 1000 simulated daily precipitation data show ability present identify probability density function....