A5084942960- Antibiotic Resistance in Bacteria
- Gallbladder and Bile Duct Disorders
- Bacterial Identification and Susceptibility Testing
- Antimicrobial Resistance in Staphylococcus
- Gastrointestinal disorders and treatments
- Diet and metabolism studies
- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- Liver Disease Diagnosis and Treatment
- Esophageal and GI Pathology
- Pediatric Hepatobiliary Diseases and Treatments
- Liver Disease and Transplantation
- Sepsis Diagnosis and Treatment
- Viral gastroenteritis research and epidemiology
- Salmonella and Campylobacter epidemiology
- Bacterial biofilms and quorum sensing
- Acute Myeloid Leukemia Research
- Nutritional Studies and Diet
- Abdominal vascular conditions and treatments
- Helicobacter pylori-related gastroenterology studies
- Enterobacteriaceae and Cronobacter Research
- Biliary and Gastrointestinal Fistulas
- Gastrointestinal Bleeding Diagnosis and Treatment
- Nephrotoxicity and Medicinal Plants
- Bioinformatics and Genomic Networks
Incheon St. Mary's Hospital
2016-2025
Catholic University of Korea
2016-2025
Chonbuk National University Hospital
2013-2025
Jeonbuk National University
2012-2025
Seoul Medical Center
2005-2023
Seoul St. Mary's Hospital
2001-2021
SK Group (South Korea)
2014
Catholic University of America
2013-2014
Pohang University of Science and Technology
2011
The University of Tokyo
2009
Heterojunction electrodes were fabricated by layer-by-layer deposition of WO3 and BiVO4 on a conducting glass, investigated for photoelectrochemical water oxidation under simulated solar light. The electrode with the optimal composition four layers covered single layer showed enhanced photoactivity 74% relative to bare 730% BiVO4. According flat band potential optical gap measurements, both semiconductors can absorb visible light have edge positions that allow transfer photoelectrons from...
An antimicrobial susceptibility test rapidly identifies bacterial response to drugs based on imaged morphology of single cells.
Abstract Human perinatal tissue is an abundant source of mesenchymal stromal cells(MSCs) and lacks the ethical concerns. Perinatal MSCs can be obtained from various tissues as like amnion, chorion, umbilical cord. Still, little known distinct nature each MSC type. In this study, we successfully isolated cultured amnion(AMSCs), chorion(CMSCs), cord(UC-MSCs). Proliferation potential was different among them, that AMSCs revealed lowest proliferation rate due to increased Annexin V...
Accumulating evidence indicates that components of the systemic inflammatory response, such as C-reactive protein (CRP) and neutrophil-to-lymphocyte ratio (NLR), have been associated with prognosis various cancers. We aimed to elucidate whether CRP NLR could serve potential surrogate markers for response survival in patients hepatocellular carcinoma (HCC).The study population consisted 318 consecutive HCC. were measured at baseline follow-up measurements.With mean 13.9 months, median time...
Abstract Background The revised definition of sepsis is life‐threatening organ dysfunction caused by a dysregulated host response to infection (SEPSIS‐3). objective this study was evaluate procalcitonin (PCT) for the diagnosis and prognosis using SEPSIS‐3. Methods We enrolled 248 patients, who were admitted emergency department with suspected bacterial from June 2016 February 2017. Definite defined proven culture results, probable based on diagnostic modalities other than culture. sequential...
Recently, resistance to extended-spectrum cephalosporins due acquired beta-lactamases has been reported in Pseudomonas aeruginosa. The aim of this study was investigate the prevalence Ambler class A and D their derivatives antimicrobial susceptibilities P. aeruginosa isolated from various parts Korea.A total 252 consecutive, non-duplicate isolates were studied for presence or beta-lactamase. Antibiotic susceptibility tests PCR amplification genes encoding (bla(PSE-1), bla(PER-1), bla(VEB-1),...
The role of clinical parameters such as systemic inflammatory response syndrome (SIRS) criteria in predicting the infection remains unclear cirrhosis patients. aim was to evaluate usefulness markers including C-reactive protein (CRP) and neutrophil-to-lymphocyte ratio (NLR) for diagnosis outcomes hospitalized cirrhotic study included 184 patients consecutively from 2011 2012. presence overt survival evaluated. CRP concentration, NLR, Model End-Stage Liver Disease (MELD) score SIRS were...
The object of this study was to evaluate biomarkers for diagnosis sepsis, hematologic parameters, and cytokine profiles use in the evaluation severity sepsis.We enrolled 127 consecutive patients with systemic inflammatory response syndrome (SIRS), 97 whom were diagnosed sepsis. following evaluated: procalcitonin (PCT); C-reactive protein (CRP); erythrocyte sedimentation rate (ESR); white blood cell count, immature granulocyte (IG) count; multiplex cytokines, including interleukin (IL)1-β...
Human mesenchymal stromal cells (MSCs) have served as a major cellular resource for cell-based immunomodulatory and regenerative therapies. However, genomic instability may accumulate during ex vivo expansion of MSCs, thereby increasing the potential malignant transformation. Here, we performed whole genome sequencing two peripheral blood-derived MSC lines (MSC1 MSC2) at various passages (passage 1 [P1] to P9). The majority single-nucleotide variations (SNVs) occurred in later passages;...
Background. The prevalence of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) strains causing bloodstream infection (BSI) has not been studied in Korea. Objective. We sought to determine the CA-MRSA among isolates recovered from patients with MRSA BSIs and explore epidemiological changes also evaluate clinical characteristics relevant development healthcare-associated BSIs. Methods. prospectively collected consecutive BSI at 4 hospitals July 1 through November 30,...
Hyeyoung Lee , M.D., Ji Hyeong Ryu B.S., Hye-Sun Park M.S., Ki Hyun Hyunjoo Bae Sojeong Yun Ae-Ran Choi Sung-Yeon Cho Chulmin Ph.D., Dong-Gun Jihyang Lim Jehoon Seungok Soyoung Shin Haeil and Eun-Jee Oh M.D.. Ann Lab Med 2019;39:566-71. https://doi.org/10.3343/alm.2019.39.6.566
A recent animal study demonstrated that administration of Lactobacillus plantarum HAC01 isolated from Korean kimchi improved glycemic control in type 2 diabetic mice. In the present study, we evaluated HAC01's effects on metabolic parameters prediabetic human subjects. Forty subjects with impaired glucose tolerance were randomly assigned to receive a daily placebo (n = 20) or dose over eight weeks. The primary endpoint was change h postprandial (2h-PPG) levels and secondary endpoints...
We evaluated the characteristics of bone marrow stromal cells (BMSCs) and hematopoietic (HCs) from patients myelodysplastic syndrome (MDS, n=21) acute myeloid leukemia (AML, n=58), compared results with control BMSCs derived healthy donors (n=8). The patient had lower proliferative activity than that controls due to increased senescence. This retarded proliferation induced failure obtain enough metaphase for karyotyping in (10%). Patient were genetically altered which was demonstrated by...
The focus of sepsis has shifted from inflammation to organ dysfunction on the basis a recent definition based sequential failure score (SOFA). A diagnostic and prognostic marker is necessary under this but currently unknown. We enrolled 80 patients consecutively admitted an intensive care unit through emergency department healthy control who received routine health check-ups August 2018 January 2019. SEPSIS-3 criteria were used for diagnosis <mml:math...
Excessive alcohol consumption is one of the most significant causes morbidity and mortality worldwide. Alcohol oxidized to toxic carcinogenic acetaldehyde by dehydrogenase (ADH) further a non-toxic acetate aldehyde (ALDH). There are two major ALDH isoforms, cytosolic mitochondrial, encoded ALDH1 ALDH2 genes, respectively. The polymorphism associated with flushing response use. Emerging evidence shows that Lactobacillus Bifidobacterium species encode (ALDH) mediate metabolism, A randomized,...
Dong Wook Jekarl, M.D., Hyunyu Choi, B.S., Seungok Lee, Jung Hyun Kwon, Sung Won Hein Yu, M.T., Myungshin Kim, Yonggoo Pil Soo Sung, and Seung Kew Yoon, M.D.. Ann Lab Med 2018;38:348-54. https://doi.org/10.3343/alm.2018.38.4.348
Probiotics have been shown to enhance cognitive function in individuals with mild impairment (MCI), but their efficacy varies, depending on the strain and dosage. Clinical investigations are crucial confirm safety, efficacy, mechanism of action. This study was designed assess effective dosage, MH-Pro, a test product containing Lacticaseibacillus rhamnosus CBT-LR5 (LR5) skim milk (non-fat dry milk), improving related physiological changes older adults suspected MCI over 12 weeks. In total, 20...
Background Stroke recovery is influenced by genetics, biochemical markers, and rehabilitation. This study examines their combined impact on early upper limb in stroke patients. Methods Forty-eight ischemic or hemorrhagic patients were assessed using the Purdue Pegboard Score (PPS) Fugl-Meyer Assessment (FMA) at admission discharge. Genetic analysis included selected SNPs (APOE, CRP, PTGS2, IGF1, etc.). Biochemical markers (vitamin B12, folate, homocysteine, cholesterol, vitamin D) measured....
Background: Sepsis is a life-threatening condition of organ dysfunction caused by dysregulated host immune response to infection.We performed network analysis cytokine molecules and compared structures between systematic inflammatory syndrome (SIRS) or normal control (NC) group sepsis group.Results: We recruited SIRS (n = 33) 89) patients from electronic medical records (EMR) according whether data on PCT, CRP, interleukin (IL)-1, IL-2, IL-4, IL-5, IL-6, IL-9, IL-10, IL-12p70, IL-13, IL-17,...