A5082230912- Advanced MRI Techniques and Applications
- Functional Brain Connectivity Studies
- Advanced Neuroimaging Techniques and Applications
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Neuroscience and Neuropharmacology Research
- MRI in cancer diagnosis
- Neurological Disease Mechanisms and Treatments
- Biochemical effects in animals
- Ultrasound and Hyperthermia Applications
- Neuroendocrine regulation and behavior
- Advanced NMR Techniques and Applications
- Prenatal Substance Exposure Effects
- Diet and metabolism studies
- Olfactory and Sensory Function Studies
- Bipolar Disorder and Treatment
- Microwave Imaging and Scattering Analysis
- Schizophrenia research and treatment
- Cannabis and Cannabinoid Research
- Cardiac electrophysiology and arrhythmias
- Nutrition, Genetics, and Disease
- Neurological Disorders and Treatments
Czech Academy of Sciences, Institute of Scientific Instruments
2017-2025
Brno University of Technology
2019
Clinical studies consistently report structural impairments (i.e.: ventricular enlargement, decreased volume of anterior cingulate cortex or hippocampus) and functional abnormalities including changes in regional cerebral blood flow individuals suffering from schizophrenia, which can be evaluated by magnetic resonance imaging (MRI) techniques. The aim this study was to assess perfusion several schizophrenia-related brain regions using Arterial Spin Labelling MRI (ASL MRI, 9.4 T Bruker...
Abstract Purpose Focused ultrasound‐induced blood–brain barrier (BBB) opening is a promising method for neurotherapeutic delivery. The standard quantifying induced BBB permeability the parameter, which reflects both and plasma flow. influence of flow can be eliminated by estimating PS parameter. However, this parameter has been largely unexplored in application. This study aims to compare estimates based on focused ultrasound–induced experiments. Methods We used extended Tofts model (ETM)...
The aim of this study is to design a method myocardial T1 quantification in small laboratory animals and investigate the effects spatiotemporal regularization needed acquisition duration.We propose compressed-sensing approach based on self-gated inversion-recovery radial two/three-dimensional (2D/3D) golden-angle stack-of-stars with image reconstruction performed using total-variation regularization. was tested phantom healthy rat, as well rats myocardium-remodeling study.The results showed...
Pilot study validating the animal model of depression - bilateral olfactory bulbectomy in rats by two nuclear magnetic resonance methods, indirectly detecting metabolic state brain. Furthermore, focussed on potential differences brain laterality.Arterial spin labelling assessed cerebral flow prefrontal, sensorimotor, and piriform cortices, nucleus accumbens, hippocampus, thalamus, circle Willis, whole Proton spectroscopy provided information about relative metabolite concentrations cortex...
Myocardial remodelling involves structural and functional changes in the heart, potentially leading to heart failure. The deoxycorticosterone acetate (DOCA)/salt model is a widely used experimental approach study hypertension-induced cardiac remodelling. It allows investigate mechanisms underlying myocardial fibrosis hypertrophy, which are key contributors impaired function. In this study, rat acetate/salt was examined over three-week period. experiment involved 11 male Sprague-Dawley rats,...