A5100628519- Catalytic C–H Functionalization Methods
- Catalytic Cross-Coupling Reactions
- Radical Photochemical Reactions
- Molecular Sensors and Ion Detection
- Sulfur-Based Synthesis Techniques
- Quinazolinone synthesis and applications
- Carbon dioxide utilization in catalysis
- Luminescence and Fluorescent Materials
- Oxidative Organic Chemistry Reactions
- Asymmetric Hydrogenation and Catalysis
- Advanced Photocatalysis Techniques
- Electrocatalysts for Energy Conversion
- Analytical Chemistry and Sensors
- Fluorine in Organic Chemistry
- Synthesis and Catalytic Reactions
- Crystallization and Solubility Studies
- Sulfur Compounds in Biology
- Organometallic Complex Synthesis and Catalysis
- Advanced biosensing and bioanalysis techniques
- Supercapacitor Materials and Fabrication
- Synthesis and pharmacology of benzodiazepine derivatives
- Electrochemical sensors and biosensors
- X-ray Diffraction in Crystallography
- Chemical Synthesis and Reactions
- CO2 Reduction Techniques and Catalysts
Qilu University of Technology
2018-2025
Shandong Academy of Sciences
2018-2025
Xinjiang Agricultural University
2024-2025
Jiangnan University
2023-2025
Nanjing Tech University
2024
Institute of New Materials
2021-2024
Taizhou Municipal Hospital
2020-2024
Lanzhou Institute of Chemical Physics
2024
Chinese Academy of Sciences
2024
University of Nottingham
2024
Boron difluoride compounds are light emitting materials with impressive optical properties. Though their strong one- and two-photon absorption intense fluorescence well-known exploited in molecular probes, lasers, photosensitizers, phosphorescence, contrast, is typically observed only at low temperatures. Here, we report that unusual room-temperature phosphorescence achieved by combining a classic boron dye, difluoroboron dibenzoylmethane, BF2dbm, poly(lactic acid) (PLA), common biopolymer,...
A palladium-catalyzed cyanation of the 3-position indole sp(2) C-H bonds by combination NH(4)HCO(3) and DMSO as "CN" source was achieved to provide aromatic nitriles in moderate good yields with excellent regioselectivity. It represents a practical safe method.
The new routes and strategies for the synthesis of valuable 4(3<italic>H</italic>)-quinazolinones have been summarized.
A simple copper-mediated cyanation of aryl halide with the combination ammonium bicarbonate and N,N-dimethylformamide as a cyanide source is achieved, providing nitriles in moderate to good yields. This new approach represents an exceedingly practical safe method for synthesis nitriles.
Abstract The CF 3 group is an omnipresent motif found in many pharmaceuticals, agrochemicals, catalysts, materials, and industrial chemicals. Despite well‐established trifluoromethylation methodologies, the straightforward selective introduction of such groups into (hetero)arenes using available less expensive sources still a major challenge. In this regard, synthesis various trifluoromethyl‐substituted by palladium‐catalyzed C−H functionalization herein reported. This novel methodology...
Abstract A new approach for the facile synthesis of fused quinazolinone scaffolds through a palladium‐catalyzed carbonylative coupling followed by an intramolecular nucleophilic aromatic substitution is described. The base serves as key modulator: Whereas DBU gives rise to linear isomers, Et 3 N promotes preferential formation angular products. Interestingly, light‐induced 4+4 reaction product was also observed.
Abstract Herein, an environmentally friendly electrochemical approach is reported that takes advantage of the captodative effect and delocalization to generate nitrogen‐centered radicals (NCRs). By changing reaction parameters electrode material feedstock solubility, dearomatization enabled a selective dehydrogenative C−N versus N−N bond formation reaction. Hence, pyrido[1,2‐ ]benzimidazole tetraarylhydrazine frameworks were prepared through sustainable transition‐metal‐ exogenous...
Abstract The design of highly efficient and stable electrocatalysts for large‐current‐density hydrogen evolution reactions (HER) is an urgent need commercial industrial electrolyzers. Herein, a novel heterostructure in the form Pd 4 S/Pd 3 P 0.95 constructed through interfacial engineering, which inherits intrinsic merits individual components exposes active sites. Density functional theory (DFT) calculations indicate that optimized not only possesses largest conductivity adsorption energy...
Mesoporous silica nanoparticles grafted with light-responsive polymer on the outer surface were developed as novel nanogated ensembles, which allow encapsulation and release of drug biological molecules under light irradiation.
Abstract A copper‐catalyzed formylation reaction has been developed by employing oxygen (O 2 ) as the clean oxidant. The CH bonds of indoles were C‐3‐formylated tetramethylethylenediamine (TMEDA) and water (H O; in situ formed external added water) carbonyl source moderate to good yields with functional group tolerance. Thus, it represents a facile procedure leading 3‐formylindoles.
Abstract A novel palladium‐catalyzed CO‐gas‐ and autoclave‐free protocol for the synthesis of 11 H ‐pyrido[2,1‐ b ]quinazolin‐11‐ones has been developed. Quinazolinones, which are omnipresent motif in many pharmaceuticals agrochemicals, were prepared good yields by CH bond activation annulation using DMF as CO surrogate. 13 CO‐labelled control experiment demonstrated that gas was released from carbonyl with acid promotor. The kinetic isotope effect (KIE) value indicated step may not be...
Abstract Dearomatization reactions represent a versatile approach for the preparation of three‐dimensionally (3D) privileged cyclic moieties from simple planar aromatic compounds. However, exogeneous oxidants are required most radical and oxidative dearomatizations. Therefore, sustainable procedures in high demand, especially those absence external oxidizing reagents. Fortunately, electrolytic dearomatization protocols can fulfill above requirements due to manipulation traceless electrons...
Abstract We describe here a novel procedure for the synthesis of highly substituted 2‐quinolinones. By this newly developed approach, 2‐quinolinone derivatives were prepared in moderate to good yields by carbonylative cyclization N ‐aryl‐pyridine‐2‐amines and internal alkynes CH activation. Remarkably, [Mo(CO) 6 ] was applied as solid CO source reaction proceeded an atom economic manner.
A new porous organic polymer has been prepared via copolymerization of divinyl-functionalized phosphoramidite ligand and tris(4-vinylphenyl)phosphine. The was loaded with Rh(acac)CO2 to yield a supported Rh catalyst, which demonstrated good regioselectivity (l/b = 6.7–52.8) high catalytic activity (TON up 45.3 × 104) in hydroformylation terminal internal olefins. Remarkably, the heterogeneous catalyst can be reused at least 10 cycles without losing selectivity 1-hexene.
Molecular electrophotocatalysis has emerged as a powerful strategy for the development of sustainable synthetic protocols. With proof-of-concept, we exploited versatile electrophotocatalytic deaminative alkylation approach. Mechanistic investigation indicated that in situ recycling alkyl radicals was key point. Notably, ligand modification and late-stage functionalization pharmaceuticals were also established, highlighting its feasibility practical utilization.