- Pharmaceutical Practices and Patient Outcomes
- Patient Safety and Medication Errors
- Electronic Health Records Systems
- Pharmaceutical studies and practices
- Pharmacological Effects and Toxicity Studies
- Healthcare Technology and Patient Monitoring
- Pharmacovigilance and Adverse Drug Reactions
- Antibiotics Pharmacokinetics and Efficacy
- Epilepsy research and treatment
- HIV/AIDS drug development and treatment
- Pharmaceutical Economics and Policy
- Medical Malpractice and Liability Issues
- Oral and gingival health research
- Quality and Safety in Healthcare
- Drug-Induced Adverse Reactions
- Pharmacy and Medical Practices
- Public Health in Brazil
- Anesthesia and Sedative Agents
- Liver Disease Diagnosis and Treatment
- Food Allergy and Anaphylaxis Research
- Pneumocystis jirovecii pneumonia detection and treatment
- Medication Adherence and Compliance
- Analytical Methods in Pharmaceuticals
- Central Venous Catheters and Hemodialysis
- Reliability and Agreement in Measurement
Hospital Universitario Ramón y Cajal
2012-2024
Instituto Cajal
2022-2024
Instituto Ramón y Cajal de Investigación Sanitaria
2022-2024
Although nebulized liposomal amphotericin B (NLAB) is being used in invasive pulmonary aspergillosis (IPA) prophylaxis, no clinical trial has shown its efficacy as a therapeutic strategy. NAIFI the inaugural randomized, controlled designed to examine safety and effectiveness of NLAB (dosage: 25 mg 6 mL, three times per week for weeks) against placebo, auxiliary treatment IPA. Throughout three-year trial, thirteen patients (six NLAB, seven placebo) were included, with 61% onco-hematological...
Abstract Rationale, aims, and objectives To evaluate the effect of an electronic medication administration record (eMAR) application on rate errors in recording (ME‐MAR). Methods A before‐and‐after, quasiexperimental study was conducted a university hospital that implemented eMAR March 2014. Data collection April 2012 (pre‐) June 2014 (post‐) by two pharmacists. The ME‐MARs were analysed staff involved to identify their cause. pharmacists independently classified ME‐MARs. In case...
The American Society for Microbiology (ASM) and Spectrum are withdrawing the article mentioned below as it is an inadvertent duplicate publication: Esteban-Cartelle B, Serrano DR, Pérez Menéndez-Conde C, Vicente-Oliveros N, Álvarez-Díaz A, Abete JF, Martín-Dávila P. 2024. Stability of meropenem in portable elastomeric infusion devices: which protocol should be implemented clinical practice? Microbiol Spectr 12:e02063-23. https://doi.org/10.1128/spectrum.02063-23. This was accidentally...
ABSTRACT Meropenem has an excellent activity against gram-positive and gram-negative bacteria, including multi-resistant microorganisms. Even though meropenem is a great candidate for outpatient parenteral antimicrobial therapy (OPAT), its physicochemical stability major challenge. This work aimed to demonstrate the suitability of in OPAT by elucidating range commonly prescribed concentrations within portable elastomeric infusion devices. Physical chemical were evaluated at two used clinical...
The complexity of an electronic medication administration record (eMAR) has been underestimated by most designers in the past. Usability issues, such as poorly designed user application flow eMAR, are therefore vital importance, since they can have a negative impact on nursing activities and result poor outcomes. purpose this study was to evaluate usability eMAR during its development.A evaluation conducted development application. Two methods were used: heuristic complemented testing. Each...
Abstract Rationale, aims and objectives The aim of this study is to adapt assess the interrater reliability a potential future risk matrix for medication errors in administration recording (ME‐MAR). Methods was carried out teaching hospital. It conducted two phases. In first phase, consensus method used order published by National Patient Safety Otero et al. ME‐MAR. consisted nominal group formed four pharmacists. second multidisciplinary experts patient safety assessed adapted matrix. Five...
<h3>Background</h3> Novel information technologies are aimed mostly at reducing medicines errors. <h3>Purpose</h3> To develop and implement an electronic administration record (eMAR) in a university hospital. <h3>Materials methods</h3> The study was conducted 1118-bed Computerised prescription order entry (CPOE) fully implemented for hospitalised patients. Traditionally, once the electronically assisted prescriptions have been made, physicians print sign medical records which nurse will...
<h3>Background</h3> The emergence of new direct acting antiviral drugs (DAAs) for hepatitis C virus (HCV) has been a major advance in the treatment disease. It is interesting to see results first patients treated our setting. Purpose To evaluate effectiveness with DAAs monoinfected HCV and coinfected HIV. <h3>Material methods</h3> Retrospective observational study at university hospital Spain. All cirrhotic who started against from September 2014 until February 2015 were included. An...
<h3>Background</h3> Determining the prevalence and seriousness of interactions with oral antineoplastic agents (OAA) is essential if we want to design efficient systems that could prevent them. <h3>Purpose</h3> The aim this study was quantify assess OAA-drug OAA-food in cancer patients. <h3>Material methods</h3> An observational, cohort conducted between June 2011 May 2012 pharmacy outpatient department a general hospital. 340 patients receiving OAA were interviewed by pharmacist. Each one...
<h3>Background</h3> Drug administration is one of the most important stages in medication process. New technologies are being developed to improve patient safety. The majority studies focus on errors, but evaluation impact technology error rates has lagged behind implementation. <h3>Purpose</h3> ▶To classify and quantify errors record (MAR) before implementing an electronic drug record. identify main causes MAR errors. compare detected a surgical medical ward. <h3>Materials methods</h3> An...
<h3>Background</h3> Modules detection and warning of drug allergies is one the brackets for prescription offered by order entry systems (CPOE). This tool an important aid in to prevent potentially medication errors. However, there aren9t studies that analyse proper use these modules physicians. <h3>Purpose</h3> To quantify discrepancies allergy registered CPOE admission discharge patients records. <h3>Materials methods</h3> On day cross-sectional study a hospital with 1000 beds. The provides...
<h3>Background</h3> Medication costs are increasing, and hospital budgets small. Clinical trials an alternative for medication cost savings. <h3>Purpose</h3> To assess the savings by inclusion of patients in myeloma multiple (MM) clinical (CT). <h3>Material methods</h3> A retrospective, observational descriptive study was conducted from January 2013 to December 2015 pharmacy department a university hospital. Ongoing MM were included. Exclusion criteria were: CT without enrolled on treatment....
<h3>Background</h3> New technology can improve patient safety but also has the potential to introduce new errors and risks into healthcare delivery <h3>Purpose</h3> To evaluate effect of an electronic medication administration record (eMAR) application on rate in recording (ME-MAR). <h3>Material methods</h3> A before after, quasi-experimental study was conducted a university hospital that implementing eMAR application. implementation took place March 2014. Data collection April 2012 (pre-)...
<h3>Background</h3> Tenofovir alafenamide (TAF) is associated with less renal and bone toxicity compared tenofovir disoproxil (TDF) but elevation of cholesterol levels. In our hospital, patients were automatically changed from a regimen Eviplera (rilpivirine (RPV) +emtricitabine (FTC)+TDF) to Odefsey (FTC)+TAF). Patients informed the switch by pharmacist. Patient views on process these medication switches have been rarely explored. <h3>Purpose</h3> To assess patient satisfaction knowledge...