Roman B. Schefer

ORCID: 0000-0003-1143-9871
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About
Contact & Profiles
Research Areas
  • Microplastics and Plastic Pollution
  • Extracellular vesicles in disease
  • Recycling and Waste Management Techniques
  • Nanoparticles: synthesis and applications
  • RNA Interference and Gene Delivery
  • Advanced biosensing and bioanalysis techniques
  • Environmental DNA in Biodiversity Studies
  • Surface Modification and Superhydrophobicity
  • MicroRNA in disease regulation

ETH Zurich
2023-2025

University of Basel
2023

Plastic fate in freshwater systems is dependent on particle size, morphology, and physicochemical surface properties (e.g., charge, roughness, hydrophobicity). Environmental aging processes, such as photochemical weathering eco-corona formation due to dissolved organic matter (DOM) adsorption plastic surfaces, can alter their properties, affecting transport. While has been studied from a materials science perspective, its specific implications environmental contexts remain less understood....

10.1021/acs.est.3c04180 article EN Environmental Science & Technology 2023-09-18

Adsorption of biomacromolecules onto polymer surfaces, including microplastics (MPs), occurs in multiple environmental compartments, forming an ecocorona. Environmental DNA (eDNA), genetic material shed from organisms, can adsorb MPs which potentially either (1) promote long-range transport antibiotic resistant genes or (2) serve to gain insights into the pathways and origins by analyzing sequences on MPs. However, little is known about capacity eDNA factors that influence sorption, such as...

10.1021/acs.est.3c10825 article EN Environmental Science & Technology 2024-04-16

Abstract Extracellular vesicles (EVs) are highly interesting for the design of next-generation therapeutics. However, their preparation methods face challenges in standardization, yield, and reproducibility. Here, we describe a efficient reproducible EV method monodisperse nano plasma membrane (nPMVs), which yields 10 to 100 times more particles per cell hour than conventional methods. nPMVs produced by homogenizing giant following blebbing apoptotic body secretion induced chemical...

10.1038/s42003-023-04859-2 article EN cc-by Communications Biology 2023-05-03

Plastics used in agriculture improve productivity and resource efficiency. As they fragment over time, microplastics are unintentionally released into soil, raising concerns regarding long-term implications for soil structure fertility. Here we investigated transport their impact on through a two-year field experiment. 45 re-packed columns were installed with three treatments: indium-doped polyethylene terephthalate fragments or fibers the top 2 cm control no microplastics. Soil pore was...

10.1038/s43247-025-02237-w article EN cc-by Communications Earth & Environment 2025-04-09

Abstract The increasing exposure to nanoplastics (NPs) raises significant concerns for human health, primarily due their potential bioaccumulative properties. While NPs have recently been detected in blood, interactions with specific immune cell subtypes and impact on regulation remain unclear. In this proof‐of‐concept study, model palladium‐doped polystyrene (PS‐Pd NPs) are utilized enable single‐cell mass cytometry (CyTOF) detection. size‐dependent of carboxylate (50–200 nm) is...

10.1002/adma.202413413 article EN cc-by-nc Advanced Materials 2024-10-24

Anthropogenic contaminants can place significant stress on vegetation, especially when they are taken up into plants.

10.1039/d4en00286e article EN cc-by Environmental Science Nano 2024-01-01
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