A5061669470- Trypanosoma species research and implications
- Research on Leishmaniasis Studies
- Public Health and Social Inequalities
- Insect symbiosis and bacterial influences
- Mosquito-borne diseases and control
- Synthesis and Biological Evaluation
- Eosinophilic Disorders and Syndromes
- Vector-Borne Animal Diseases
- Biochemical and Molecular Research
National University of the Littoral
2007-2021
Centro Nacional de Investigaciones Científicas
2016
National University of Rosario
2011
The efficacy of treatment with nifurtimox and/or benznidazole among adults chronic Chagas disease no previous electrocardiographic disturbances was evaluated over a mean follow-up 21 years, by means conventional serology, xenodiagnosis, clinical examination, electrocardiograms and chest X-ray. One hundred eleven patients, between 17 46 years old, were studied: 54 underwent (nifurtimox 27, 27) 57 remained untreated (control group). Xenodiagnosis performed on 65% them: 36/38 the treated 9/34...
This work compared the time at which negative seroconversion was detected by conventional serology (CS) and ELISA-F29 test on a cohort of chronic chagasic patients treated with nifurtimox or benznidazole. A retrospective study performed using preserved serum from 66 asymptomatic adults under clinical supervision, bi-annual serological examinations over mean follow-up 23 years. Twenty nine received trypanocide treatment 37 remained untreated. The used recombinant antigen obtained expressing...
We investigated the relationship between potentially pathogenic antibodies against a Trypanosoma cruzi ribosomal protein (P2β) and evolution of Chagas disease effect trypanocidal treatment on these variables. Seventy-eight patients with chronic who were followed-up for more than 20 years divided into three groups: 30 asymptomatic persons undergoing specific (group A), 37 not B), 11 chagasic cardiomyopathy (CCC) treated. Five in group B showed to myocardial abnormalities. Among CCC, six no...
La enfermedad de Chagas, producida por el Trypanosoma cruzi y transmitida un insecto triatomino, es gran complejidad. En control esta endemia no puede considerarse la como hecho individual y solo biologico. Entre sus multiples componentes debe considerarse relacion los sujetos con habitat, los modos produccion, las condiciones culturales, las relaciones sociales formas organizativas.Como profesionales del campo salud intentamos nuevos enfoques que integran diferentes miradas disciplinares y...
American trypanosomiasis is transmitted by the bite of blood-sucking bugs Triatoma (in most cases), congenital infection, or transfusion infected blood. During acute stage it generally asymptomatic and during chronic can lead to heart problems (most commonly), digestive problems. The etiological treatment more effective in cases children under 15 with infection. Our objective was determine: a) existence young people that missed opportunity being treated because they were too old when...
The present article looks at the association between epidemiological history of women infected with Trypanosoma cruzi and risk vertical transmission. Eighty-three chronically mothers their 237 children were studied, using a cohort design. All patients reside in Santa Fe city, Argentina. Twenty-five transmitted infection to 38 children. potential factors evaluated exposure vector transmission, bloodtransfusion history, maternal seropositivity, parasitemia age birth child. 72% (18/25) who...
The direct agglutination technique for chagasic infection diagnosis is easy to performand inexpensive. It has good sensitivity and specificity when used in conjunctionwith other serological and/or parasitological techniques. been replaced withother reactions with faster results easiness read (i.e. immunoenzymaticassay (ELISA) indirect hemagglutination). Currently it difficult obtaincommercial kits. In the present paper we a series of cases that show theusefulness test early determine acute...
Los anticuerpos anti-muscarínicos (anti-M2) podrían estar relacionados con alteraciones disautonómicas en la enfermedad de Chagas.Objetivo: evaluar efecto del tratamiento tripanocida sobre los anti-M2 adultos chagásicos crónicos seguidos durante 24 años promedio.Estudio cohorte retrospectivo.Infectados por T. cruzi agrupados en: A) 31 tratados drogas tripanocidas (102 muestras post-tratamiento); B) 36 no (95 muestras).Controles chagásicos: 17 cardiópatas y 22 sanos.Pacientes tratados:...