- Rheumatoid Arthritis Research and Therapies
- Chronic Disease Management Strategies
- Venous Thromboembolism Diagnosis and Management
- Blood Pressure and Hypertension Studies
- COVID-19 and healthcare impacts
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Acute Ischemic Stroke Management
- Medication Adherence and Compliance
- Medical Coding and Health Information
- Nursing Diagnosis and Documentation
- Tuberculosis Research and Epidemiology
- COVID-19 and Mental Health
- Transplantation: Methods and Outcomes
- Intensive Care Unit Cognitive Disorders
- Lipoproteins and Cardiovascular Health
- Antifungal resistance and susceptibility
- Genetic Neurodegenerative Diseases
- Anesthesia and Neurotoxicity Research
- Pharmacology and Obesity Treatment
- Anesthesia and Sedative Agents
- Parkinson's Disease Mechanisms and Treatments
- Diabetes Management and Research
- Health, Environment, Cognitive Aging
- Healthcare Policy and Management
- Attention Deficit Hyperactivity Disorder
Mayo Clinic in Arizona
2019-2025
Arizona Department of Health Services
2023-2025
Florida International University
2024
Mayo Clinic Health System
2024
Mayo Clinic
2022
Mayo Clinic in Florida
2019-2021
High-quality diabetes care is evidence-based, timely, and equitable. Sodium-glucose cotransporter-2 inhibitors (SGLT2i) are the most recently approved class of glucose-lowering medications with additional cardio- renal-protective benefits low risk hypoglycemia. Cardiovascular kidney disease among common chronic complications, whereas hypoglycemia prevalent adverse effect therapy. We examine sociodemographic clinical factors associated early SGLT2i initiation appropriateness use based on...
<h3>Importance</h3> There are limited data on the racial disparities in incidence of attention-deficit/hyperactivity disorder (ADHD) diagnosis children at national level. <h3>Objective</h3> To explore differences rates ADHD and use treatment among by race ethnicity. <h3>Design, Setting, Participants</h3> This retrospective cohort study assessed insurance claims born US between January 1, 2006, December 31, 2012, who had continuous coverage for least 4 years. The last date follow-up included...
Real-world data sources, including electronic health records (EHRs) and personal digital device data, are increasingly available, but often siloed cannot be easily integrated for clinical, research, or regulatory purposes. We conducted a prospective cohort study of 60 patients undergoing bariatric surgery catheter-based atrial fibrillation ablation at two U.S. tertiary care hospitals, testing the feasibility using patient-centered health-data-sharing platform to obtain aggregate from...
To comprehensively assess multimorbidity burden in patients with rheumatoid arthritis (RA) order to unify the definition for RA research and clinical practice. In this population-based study, residents of eight Minnesota counties prevalent on 1 January 2015 were identified. Age, sex county-matched non-RA comparators selected from same population. Diagnostic codes retrieved 5 years before 2015. Using two ≥30 days apart, 44 previously defined morbidities 78 non-overlapping chronic disease...
Guidelines for diagnosing pulmonary embolism (PE) start with a risk assessment using pretest probability (PTP) tool, followed by D-dimer testing or computed tomography angiography (CTPA) depending on risk. The project aimed to develop an electronic clinical quality measure (eCQM) encourage broader use of validated PTP scoring tool in emergency departments (EDs) more accurately diagnose PE and reduce unnecessary CTPAs. To identify value set CTPA abnormal tests standard classification systems...
ABSTRACT Introduction/Aims Healthcare utilization and costs in myotonic dystrophy (DM) are not well understood. This study describes the burden of DM its associated costs. Methods We performed a retrospective using data from large U.S. administrative claims database to identify commercially insured individuals with compared healthcare cost matched cohort. Analyses were between cohorts ≥ 3 years follow‐up. Results identified 1182 coverage at least year prior following an index diagnosis...
Rationale: Many lung transplant centers prescribe antifungal medications after transplantation to prevent invasive fungal infections (IFIs); however, the effectiveness of prophylaxis at reducing risk all-cause mortality or IFI has not been established.Objectives: We aimed evaluate effect on and in patients.Methods: Using administrative claims data, we identified adult patients who underwent between January 1, 2005, December 31, 2018. Propensity score analysis using inverse probability...
Abstract Objective To evaluate the association between statin use and risk of developing rheumatoid arthritis (RA) in a large, US case-control study. Methods Using OptumLabs Data Warehouse, RA cases were identified as patients aged ≥18 years with ≥2 diagnoses January 1, 2010 June 30, 2019 ≥1 prescription fills for methotrexate within 1 year first diagnosis. The diagnosis was index date. Cases matched 1:1 to controls on age, sex, region, date, length baseline coverage. Statin users defined by...
Multimorbidity is burdensome for people with RA. We investigated differences in multimorbidity and comorbidities by sex age the RA population.
To identify differences in multimorbidity and individual comorbidities among individuals with rheumatoid arthritis (RA), separated by race ethnicity.
ABSTRACT Real-world data sources, including electronic health records (EHR) and personal digital device data, are increasingly available, but often siloed cannot be easily integrated for clinical, research, or regulatory purposes. We conducted a prospective cohort study of 60 patients undergoing bariatric surgery catheter-based atrial fibrillation ablation at two U.S. tertiary care hospitals, testing the feasibility using patient-centered sharing platform to obtain aggregate from multiple...
The global COVID-19 pandemic presented a period of considerable stress for healthcare professionals on scale. strain facilities nationwide has resulted in profound implications the well-being numerous practitioners. A heightened demand extended working hours emerged, potentially amplifying workload these professionals. This study aims to scrutinize levels experienced by specializing family medicine at tertiary medical center. Our findings reveal persistent escalation over course study....
Background: Studies evaluating the effect of statin use on risk rheumatoid arthritis (RA) onset have shown conflicting results. Most these studies evaluated European populations while data from US are scarce. Objectives: We aimed to assess association between (and intensity) and RA occurrence using claims population. Methods: For this case-control study, we used OptumLabs Data Warehouse, a large administrative database commercially insured Medicare Advantage beneficiaries, identify cases...
To date, there has been a notable lack of peer-reviewed or publicly available data documenting rates hospital quality outcomes and patient safety events during the coronavirus disease 2019 pandemic era. The dearth evidence is perhaps related to US health care system triaging resources toward away from reporting research also reflects that used in reported rankings ratings typically lag 2-5 years. At our institution, learning assessment underway evaluate how was affected by pandemic. Here we...
Background: Multimorbidity is burdensome for people with rheumatoid arthritis (RA). We investigated differences in multimorbidity and comorbidities by sex age the RA population.Methods: This case-control analysis used national administrative claims (OptumLabs® Data Warehouse) from non-RA controls (matched on age, sex, race, census region, index date year, length of baseline insurance coverage) 2010-2019. was determined using a validated algorithm. defined as having ≥2 (MM2+) or ≥5 (MM5+) set...
Background: Patients with rheumatoid arthritis (RA) have an increased burden of multimorbidity. Although many comorbidities vary by sex, sex differences in multimorbidity among individuals RA not been examined. Objectives: We aimed to compare between women and men comparators without RA. Methods: used a large longitudinal, real-world data warehouse de-identified administrative claims for commercial Medicare Advantage enrollees, identify cases matched controls. Cases were defined as patients...
Background: Patients with rheumatoid arthritis (RA) have an increased burden of multimorbidity. Racial/ethnic disparities also been associated Objectives: We aimed to compare multimorbidity among different racial/ethnic groups and geographic regions the US in patients RA comparators without RA. Methods: used a large longitudinal, real-world data warehouse de-identified administrative claims for commercial Medicare Advantage enrollees, identify cases matched controls. Cases were defined as...