A5067868620- Health Systems, Economic Evaluations, Quality of Life
- Medication Adherence and Compliance
- Diabetes Treatment and Management
- HIV/AIDS drug development and treatment
- HIV/AIDS Research and Interventions
- Cardiac, Anesthesia and Surgical Outcomes
- Healthcare Policy and Management
- Rheumatoid Arthritis Research and Therapies
- Bariatric Surgery and Outcomes
- Pharmaceutical Practices and Patient Outcomes
- Atrial Fibrillation Management and Outcomes
- Surgical Sutures and Adhesives
- Advanced Causal Inference Techniques
- Retinal Diseases and Treatments
- Colorectal Cancer Surgical Treatments
- Hemostasis and retained surgical items
- Pharmaceutical Economics and Policy
- Surgical site infection prevention
- Chronic Lymphocytic Leukemia Research
- Retinal Imaging and Analysis
- Venous Thromboembolism Diagnosis and Management
- Gastric Cancer Management and Outcomes
- Biosimilars and Bioanalytical Methods
- Systemic Lupus Erythematosus Research
- Antiplatelet Therapy and Cardiovascular Diseases
Johnson & Johnson (United States)
2017-2025
Northwestern University
2011-2024
York Hospital
2024
University of Mississippi Medical Center
2024
Jackson Memorial Hospital
2024
Midland Regional Hospital at Tullamore
2023
NHS Lothian
2023
Diagnostics for the Real World (United States)
2022
Museum of Heilongjiang Province
2021
Johnson & Johnson (Israel)
2017-2020
Detailed information on the cost burden of atrial fibrillation (AF) is limited. To provide an up-to-date estimate national AF, we conducted a retrospective, observational cohort study using administrative claims from MarketScan Commercial and Medicare Supplemental research data bases, 2004 to 2006.Patients aged ≥20 years with ≥1 inpatient or ≥2 outpatient AF diagnoses in 2005 (first diagnosis=index) ≥12 months' enrollment before after index were selected. patients propensity score-matched...
Hip fractures are common, morbid, costly, and associated with subsequent fractures. Historically, postfracture osteoporosis medication use rates have been poor, but not recently examined in a large-scale study. We conducted retrospective, observational cohort study based on U.S. administrative insurance claims data for beneficiaries commercial or Medicare supplemental health insurance. Eligible participants were hospitalized hip fracture between January 1, 2002, December 31, 2011, aged 50...
Aims: This retrospective observational study examined the association between International Classification of Diseases, Ninth Revision, Clinical Modification (ICD‐9‐CM)‐coded outpatient hypoglycaemic events and fall‐related fractures in Medicare‐covered patients with type 2 diabetes. Methods: Data were derived from healthcare claims for individuals employer‐sponsored Medicare supplemental insurance. The period consisted two consecutive 1‐year periods; baseline (1 April 2008 to 31 March 2009)...
This retrospective study examined the association between ICD-9-CM-coded outpatient hypoglycemic events (HEs) and acute cardiovascular (ACVEs), i.e., myocardial infarction, coronary artery bypass grafting, revascularization, percutaneous intervention, incident unstable angina, in patients with type 2 diabetes.Data were derived from healthcare claims for individuals employer-sponsored primary or Medicare supplemental insurance. A baseline period (30 September 2006 to 30 2007) was used...
Abstract BACKGROUND: Patients hospitalized for medical illness are at increased risk of venous thromboembolism (VTE), but the duration is not well understood. OBJECTIVE: To assess incidence and time course symptomatic VTE following hospitalization in a large, real‐world patient population. DESIGN: Data were extracted from Thomson Reuters MarketScan ® Inpatient Drug Link File. PATIENTS: Those with cancer, heart failure, severe lung disease, or infectious disease 2005 to 2008. MEASUREMENTS:...
Abstract The prevalence of obesity has grown rapidly over the past several decades and been accompanied by an increase in chronic pain prescription opioid use. Obesity, through its association with pain, may represent important contributor to This cross-sectional study investigated relationship between use among adults aged 35 79 years using data from National Health Nutrition Examination Survey (NHANES, 2003-2016). Relative normal weight, body mass indices overweight {odds ratio (OR), 1.11...
Real-world data sources, including electronic health records (EHRs) and personal digital device data, are increasingly available, but often siloed cannot be easily integrated for clinical, research, or regulatory purposes. We conducted a prospective cohort study of 60 patients undergoing bariatric surgery catheter-based atrial fibrillation ablation at two U.S. tertiary care hospitals, testing the feasibility using patient-centered health-data-sharing platform to obtain aggregate from...
Objective: To quantify and compare direct costs, utilization, the rate of comorbidities in a sample patients with fibromyalgia (FM), poorly understood illness associated chronic widespread pain that is commonly treated by rheumatologists, to rheumatoid arthritis (RA), well studied rheumatologic inflammatory joint pain. Patients both illnesses were isolated reported as third group. A secondary analysis work loss was performed for an employed subset these patients.Research design methods:...
To evaluate the incidence and prevalence of extra-articular (ExRA) systemic (SysM) manifestations in a cohort newly-diagnosed patients with rheumatoid arthritis (RA) United States.Retrospective analysis using inpatient, outpatient, pharmacy claims data contained Thomson Healthcare MarketScan research databases. Patients >or= 18 years age diagnosis RA (ICD-9-CM 714.0x) on three non-diagnostic different days between January 1, 1999 September 30, 2006, at least 12 months continuous enrollment...
Patients with type 2 diabetes mellitus (T2DM) must remain adherent and persistent on antidiabetic medications to optimize clinical benefits. This analysis compared adherence persistence among adults initiating dipeptidyl peptidase-4 inhibitors (DPP-4is), sulfonylureas (SUs), thiazolidinediones (TZDs) between patients saxagliptin or sitagliptin, two DPP-4is. retrospective cohort study utilized the US MarketScan® (Truven Health Analytics, Ann Arbor, MI, USA) Commercial Medicare Supplemental...
To examine, among patients with type 2 diabetes, the association between hospitalization for heart failure (hHF) and treatment dipeptidyl peptidase 4 inhibitors (DPP-4is) versus sulfonylureas (SUs), saxagliptin sitagliptin.This was a retrospective, observational study using U.S. insurance claims database. Patients initiated 1 August 2010 30 2013, had no use of comparator treatments in prior 12 months (baseline). Each comparison consisted matched 1:1 on propensity score. Time to each outcome...
OBJECTIVE Understanding how changes in weight over the life course shape risk for diabetes is critical prevention of diabetes. Using data from National Health and Nutrition Examination Survey (NHANES), we investigated association between self-reported change young adulthood to midlife incident RESEARCH DESIGN AND METHODS We categorized individuals into four weight-change groups: those who remained nonobese (stable nonobese), moved an obese BMI a (losing), (gaining), obese). Diabetes status...
Bleeding is a significant complication in cardiac surgery and associated with substantial morbidity mortality. This study evaluated the impact of bleeding on length stay (LOS) critical care utilization nationwide sample patients treated at English hospitals. Retrospective, observational cohort using linked Hospital Episode Statistics (HES) Clinical Practice Research Datalink (CPRD) records for aged ≥18 years who underwent coronary artery bypass graft (CABG), valve repair/replacement, or...
Abstract Purpose To quantify the sensitivity and positive predictive value (PPV) of body mass index (BMI)‐related ICD‐9‐CM ICD‐10‐CM diagnosis codes in claims data. Methods De‐identified electronic health record (EHR) data were obtained from Optum Integrated Claims‐Clinical Database for cross‐sections commercial Medicare Advantage plan members age ≥ 20 years 2013, 2014, 2016. In each calendar year, members' BMI as coded insurance (error‐prone measure) was compared with their recorded EHR...
Cesarean delivery is the most common major operating room procedure performed in United States. Wound closure after cesarean includes suturing for uterine and to close fascial-and sometimes subcutaneous-tissue layer followed by skin closure. Optimal critical as it affects risk of both wound infection dehiscence. To our knowledge, however, no clinical or real-world studies comparing 2OPMT with conventional sutures following have been published date. We sought compare economic outcomes...
Aim: Trends in the use and comparative outcomes for barbed conventional sutures have not been well-reported robotic surgery. Materials & methods: This retrospective study used hospital discharge data US to assess suture during colorectal surgery (CR), total hysterectomy (TH) ventral hernia repair (VHR) performed between 1 October 2015 30 June 2022. We first examined quarterly trends of sutures, (specifically STRATAFIX™ knotless tissue control devices [KTCD]) then compared clinical...
The ATHENA trial (A placebo-controlled, double-blind, parallel arm Trial to assess the efficacy of dronedarone 400 mg bid for prevention cardiovascular Hospitalization or death from any cause in patiENts with Atrial fibrillation/atrial flutter) demonstrated that reduced risk (CV) hospitalization/death by 24% (P < 0.001) patients atrial fibrillation (AF) and flutter (AFL).In order estimate cost savings associated use, we estimated costs CV hospitalizations inpatient mortality a large cohort...
Quantify the incremental health care costs and workplace absence short-term disability costs, to payers employers, of patients hospitalized for acute coronary syndrome (ACS).Retrospective study using medical insurance claims years 2002 2007. Patients were aged 18 64 ACS between January 1, 2003, December 31, 2006; comparison without evidence artery disease also selected. The impact was estimated weighted regression.30,200 Incremental annual direct $40,671 (P < 0.001). For indirect cost...