Laura Goldstein

ORCID: 0000-0002-7847-0905
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About
Contact & Profiles
Research Areas
  • Atrial Fibrillation Management and Outcomes
  • Cardiac Arrhythmias and Treatments
  • Health Systems, Economic Evaluations, Quality of Life
  • Cardiac electrophysiology and arrhythmias
  • Cardiac pacing and defibrillation studies
  • Liver Disease and Transplantation
  • Organ Transplantation Techniques and Outcomes
  • Colorectal Cancer Surgical Treatments
  • Colorectal Cancer Screening and Detection
  • Cardiac, Anesthesia and Surgical Outcomes
  • Shoulder and Clavicle Injuries
  • Surgical Sutures and Adhesives
  • Pleural and Pulmonary Diseases
  • Shoulder Injury and Treatment
  • Lung Cancer Diagnosis and Treatment
  • Economic and Financial Impacts of Cancer
  • Blood Pressure and Hypertension Studies
  • Esophageal Cancer Research and Treatment
  • Venous Thromboembolism Diagnosis and Management
  • Surgical site infection prevention
  • Cancer Diagnosis and Treatment
  • Breast Implant and Reconstruction
  • Cardiovascular Syncope and Autonomic Disorders
  • Abdominal Surgery and Complications
  • Digital Imaging in Medicine

Johnson & Johnson (United States)
2018-2024

Beth Israel Deaconess Medical Center
2020

Harvard University
2020

University of California, Los Angeles
1988

Los Angeles Medical Center
1988

This study identified factors associated with risk for cardiac perforation in the setting of atrial fibrillation (AF) ablation contemporary clinical practice.Cardiac is an uncommon but potentially fatal complication AF ablation. An improved understanding could facilitate improvements procedural safety.Logistic regression models were used to assess predictors among Medicare beneficiaries who underwent from July 1, 2013 and December 31, 2017. Cardiac was defined as a diagnosis hemopericardium,...

10.1016/j.jacep.2020.01.011 article EN cc-by-nc-nd JACC. Clinical electrophysiology 2020-03-25

Abstract Introduction Research evidence has shown that catheter ablation is a safe and superior treatment for atrial fibrillation (AF) compared to medical therapy, but real‐world practice been slow adopt an early interventional approach. This study aims determine the cost effectiveness of therapy from perspective United Kingdom. Methods A patient‐level Markov health‐state transition model was used conduct cost‐utility analysis. The population included patients previously treated AF with...

10.1111/jce.15317 article EN Journal of Cardiovascular Electrophysiology 2021-12-12

By providing real-time monitoring of catheter-tissue interface and for complications, intracardiac echocardiography (ICE) during catheter ablation ventricular tachycardia (VT) may improve outcomes. To test this hypothesis, we compared 12-month readmission rates (all-cause, cardiovascular [CV]-related, VT-related), repeat ablation, complications among patients with VT structural heart disease undergoing versus without ICE.Using the 2008-2017 IBM MarketScan Commercial Medicare Supplemental...

10.1111/jce.14324 article EN Journal of Cardiovascular Electrophysiology 2019-12-23

Ablation reduces atrial fibrillation (AF) burden and improves health-related quality of life. The relationship between ablation, healthcare utilization, AF type (paroxysmal [PAF] vs persistent [PsAF]) remains unclear.To compare changes in AF-related utilization costs from preablation to postablation among patients with PAF PsAF.Patients (2794 PAF, 1909 PsAF) undergoing ablation (2016-2018) were identified using the Optum database. Outcomes included inpatient admissions, emergency department...

10.1016/j.hroo.2020.12.017 article EN cc-by-nc-nd Heart Rhythm O2 2020-12-16

National guidelines recommend against continuous pulse oximetry use for hospitalized children with bronchiolitis who are not receiving supplemental oxygen, yet guideline-discordant remains high.To evaluate deimplementation outcomes of educational outreach and audit feedback strategies aiming to reduce in oxygen.A nonrandomized clinical single-group trial was conducted 14 non-intensive care units 5 freestanding children's hospitals 1 community hospital from December 1, 2019, through March 14,...

10.1001/jamanetworkopen.2021.22826 article EN cc-by-nc-nd JAMA Network Open 2021-09-02

The objective of our study was to compare resource use and clinical outcomes among atrial fibrillation (AF) patients who underwent catheter ablation versus antiarrhythmic drug (AAD) treatment. A retrospective cohort design using the Clinical Practice Research Data-Hospital Episode Statistics linkage data from England (2008–2013) used. Patients undergoing treatment for AF were indexed date first procedure. AAD with at least two different drugs fill second AAD. matched 1:1 propensity matching....

10.1186/s12872-018-0946-6 article EN cc-by BMC Cardiovascular Disorders 2018-11-07

Abstract Background Catheter ablation (CA) is a common treatment for atrial fibrillation (AF). This study evaluated outcomes of same day discharge (SDD) versus overnight stay (ONS) among AF patients undergoing outpatient CA. Methods The Optum SES Clinformatics Extended Data Mart database was used to identify ≥18 years age CA (2016–2020). Eligible were indexed the date first and classified into SDD ONS groups based on length service. A 1:3 propensity score matching create comparable SDD:ONS...

10.1111/jce.15193 article EN Journal of Cardiovascular Electrophysiology 2021-07-29

Abstract Introduction Perioperative complications impose both a clinical and financial burden on patients the healthcare system. This study sought to identify frequency economic impact of following orthotopic liver transplantation ( OLT ). Methods The Premier Perspective ® Hospital Database was queried for undergoing between 2008 2015. Complications were identified by ICD ‐9 code grouped complication type. Complication as well outcomes calculated. effect cost combined determine annual each...

10.1111/ctr.13209 article EN Clinical Transplantation 2018-01-24

Objectives: The economic burden of surgical complications is borne in distinctly different ways by hospitals and payers. This study quantified the incidence – from both hospital payer perspective selected major colorectal surgery patients undergoing low anterior resection (LAR) for cancer.Methods: Retrospective, observational patient LAR cancer between 1/1/2010 7/1/2015. Analyses were replicated two large healthcare administrative databases: Premier (hospital discharge billing data;...

10.1080/21548331.2019.1568718 article EN Hospital Practice 2019-01-11

Abstract Purpose Real-world data can help medical administrators, physicians, and payers make evidence-based decisions regarding treatment choices. The objective of this study was to compare real-world safety outcomes with the latest catheter technologies used for atrial fibrillation (AF). Methods Vizient Health Systems database, a large US hospital acute complications in AF ablation contact force sensing THERMOCOOL SMARTTOUCH® Catheter or SF (ST) versus second-generation Arctic Front...

10.1007/s10840-020-00734-w article EN cc-by Journal of Interventional Cardiac Electrophysiology 2020-05-11

To determine hospital resource utilization, associated costs and the risk of complications during hospitalization for four types surgical resections to estimate incremental burden among patients with cancer compared those without cancer. Patients (≥18 years old) were identified from Premier Research Database US hospitals if they had any following elective between 1/2008 12/2014: lung lobectomy, lower anterior resection rectum (LAR), liver wedge resection, or total hysterectomy. Cancer status...

10.1186/s13561-017-0160-8 article EN cc-by Health Economics Review 2017-06-02

Abstract Background Catheter ablation is an effective treatment for patients with atrial fibrillation (AF) and heart failure (HF). However, little known about how healthcare utilization cost change after in this population. We sought to determine patterns among AF HF undergoing ablation. Methods Using a large United States administrative database, we identified ( n = 1568) treated primary secondary diagnosis of HF, respectively, were evaluated 1‐year pre‐ postablation outcomes including...

10.1111/jce.14774 article EN cc-by-nc-nd Journal of Cardiovascular Electrophysiology 2020-10-06

Abstract Background Catheter ablation (CA) has emerged as an effective treatment for symptomatic atrial fibrillation (AF). However practice patterns and patient factors associated with referral CA within the first 12 months after diagnosis are poorly characterized. This study examined overall procedural trends predictive of catheter newly-diagnosed in a young, commercially-insured population. Methods A large nationally-representative sample patients age 20 to 64 from years 2010 2016 was...

10.1186/s12872-020-01446-9 article EN cc-by BMC Cardiovascular Disorders 2020-04-06

Catheter ablation (CA) has emerged as an effective therapy for the treatment of paroxysmal atrial fibrillation (AF); however it is unclear whether proceeding expeditiously to CA improves clinical outcomes in a real-world population. This study compares new AF within 6 months diagnosis (very early) 12 after (early) and 24 (later).A large nationally-representative sample patients ages 18 64 who underwent from January 2011 June 2019 was studied using IBM MarketScan Database. The primary outcome...

10.1111/pace.14459 article EN Pacing and Clinical Electrophysiology 2022-02-12

Goldstein, Laura J. JD, MSPH; Chary, Dilip MD, MBA; Brennan, Siobhan BMed Sci, PhD Author Information

10.1097/psn.0000000000000023 article EN Plastic Surgical Nursing 2014-01-01

Aim: To compare outcomes among patients with implantable cardioverter defibrillator/cardiac resynchronization therapy-defibrillator undergoing outpatient ventricular tachycardia (VT) catheter ablation using intracardiac echocardiography (ICE) versus no ICE. Patients & methods: were classified into ICE (n = 1143)/non-ICE 1677) groups based on procedure codes. in each group propensity matched study covariates. Survival analyses used to assess outcomes. examine residual confounding,...

10.2217/cer-2019-0156 article EN Journal of Comparative Effectiveness Research 2020-03-05

As same-day discharge (SDD) after catheter ablation (CA) for atrial fibrillation (AF) is increasingly utilized, it important to further investigate this approach.To the safety and efficacy of SDD CA AF in a large nationwide administrative sample.The IBM MarketScan Commercial Claims Encounters database was used identify adult patients under 65 years undergoing (2016-2020). Eligible were indexed date first classified into or overnight stay (ONS) groups based on length service. A 1:3 propensity...

10.1016/j.hroo.2021.07.001 article EN cc-by Heart Rhythm O2 2021-07-14

Data on the 1-year postoperative revision, complication, and economic outcomes in a hospital setting after total shoulder arthroplasty (TSA) are sparse.

10.1016/j.jse.2024.05.009 article EN cc-by Journal of Shoulder and Elbow Surgery 2024-06-01

Abstract Introduction To date, the financial burden of biliary strictures ( BS ) after orthotopic liver transplantation OLT has remained largely unassessed. This study sought to approximate perioperative costs associated with early and delineate where in hospital these are incurred. Methods The Premier Healthcare Database was queried for patients undergoing between 2010 2016. Patients who did not develop were compared respect outcome variables. Multivariable regression models used estimate...

10.1111/ctr.13396 article EN Clinical Transplantation 2018-08-30
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