- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Cardiovascular Syncope and Autonomic Disorders
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Sarcoidosis and Beryllium Toxicity Research
- Coronary Interventions and Diagnostics
- Heart Rate Variability and Autonomic Control
- Cardiomyopathy and Myosin Studies
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Valve Diseases and Treatments
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular Function and Risk Factors
- ECG Monitoring and Analysis
- Lipoproteins and Cardiovascular Health
- Antiplatelet Therapy and Cardiovascular Diseases
- Viral Infections and Immunology Research
- Infective Endocarditis Diagnosis and Management
- Cardiac Arrest and Resuscitation
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Blood Pressure and Hypertension Studies
- Advanced MRI Techniques and Applications
- Cardiovascular Effects of Exercise
Beth Israel Deaconess Medical Center
2016-2025
Harvard University
2016-2025
Deaconess Hospital
2016-2025
Mount Sinai Beth Israel
2024
Virginia Commonwealth University
2022-2024
University of Michigan
2022-2024
Baum Consult
2005-2023
Hadassah Medical Center
2002-2020
Beth Israel Deaconess Hospital
1997-2018
Cleveland Clinic
2017
Administration of hydroxychloroquine with or without azithromycin for the treatment coronavirus disease 2019 (COVID-19)-associated pneumonia carries increased risk corrected QT (QTc) prolongation and cardiac arrhythmias.
We sought to investigate the impact of multivessel coronary artery disease (CAD) on reperfusion success and prognosis following primary percutaneous intervention (PCI) in patients with acute myocardial infarction (AMI). The influence subsequent survival after PCI has not been studied. In CADILLAC trial, was performed 2082 any age AMI within 12 h symptom onset. Myocardial perfusion post-PCI assessed by ST-segment recovery blush clinical outcomes were stratified extent CAD. Single-, double-,...
Although extending the duration of ambulatory electrocardiographic monitoring beyond 24 to 48 hours can improve detection arrhythmias, lead-based (Holter) monitors might be limited by patient compliance and other factors. We, therefore, evaluated compliance, analyzable signal time, interval arrhythmia detection, diagnostic yield Zio Patch, a novel leadless, device in 26,751 consecutive patients. The mean wear time was 7.6 ± 3.6 days, median 99% total time. Among patients with detected...
Sudden death is one of the more frequent causes for hemodialysis patients, but underlying mechanisms, contribution arrhythmia, and associations with serum chemistries or dialysis procedure are incompletely understood. To study this, implantable loop recorders were utilized continuous cardiac rhythm monitoring to detect clinically significant arrhythmias including sustained ventricular tachycardia, bradycardia, asystole, symptomatic in patients over six months. Serum tested pre- post-dialysis...
AimsPredictors of Response to Cardiac Resynchronization Therapy (CRT) (PROSPECT) was the first large-scale, multicentre clinical trial that evaluated ability several echocardiographic measures mechanical dyssynchrony predict response CRT. Since CRT may be defined as a spectrum and likely influenced by many factors, this sub-analysis aimed investigate relationship between baseline characteristics
Aims ST-segment recovery (ΣSTR) and myocardial blush (MB) evaluate different elements of microcirculatory integrity after reperfusion therapy in acute infarction (AMI). We sought to determine whether the combination ΣSTR MB primary percutaneous coronary intervention (PCI) AMI has greater prognostic utility than either measure alone.
Background— Stratifiers of sudden and total mortality risk are needed to optimally target preventive therapies in patients with coronary artery disease impaired ventricular function. We assessed the prognostic significance ECG markers conduction abnormalities left hypertrophy Multicenter Unsustained Tachycardia Trial (MUSTT). Methods Results— analyzed ECGs 1638 from MUSTT who did not receive antiarrhythmic therapy (antiarrhythmic medication or implantable cardioverter-defibrillator). After...
Background Outpatient ambulatory cardiac rhythm monitoring is a routine part of the management patients with paroxysmal atrial fibrillation (AF). Current systems are limited by patient convenience and practicality . Methods We compared Zio ® Patch, single‐use, noninvasive waterproof long‐term continuous patch, 24‐hour Holter monitor in 74 consecutive AF referred for detection arrhythmias Results The Patch was well tolerated, mean period 10.8 ± 2.8 days (range 4–14 days). Over period, there...
Background— Radiofrequency catheter ablation (RFA) has emerged as an important treatment strategy for atrial fibrillation (AF). The potential cost-effectiveness of RFA AF, relative to antiarrhythmic drug (AAD) therapy, not been fully explored from a US perspective. Methods and Results— We constructed Markov disease simulation model hypothetical cohort patients with drug-refractory paroxysmal treated either with/without AAD or alone. Costs quality-adjusted life-years were projected over 5...