- Cardiac Structural Anomalies and Repair
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Diversity and Career in Medicine
- Cardiovascular Issues in Pregnancy
- Cerebrovascular and Carotid Artery Diseases
- Cardiac Arrhythmias and Treatments
- Cardiovascular Function and Risk Factors
- Cardiovascular Health and Disease Prevention
- Dementia and Cognitive Impairment Research
- Blood Pressure and Hypertension Studies
- Cardiac electrophysiology and arrhythmias
- Cardiac, Anesthesia and Surgical Outcomes
- Healthcare professionals’ stress and burnout
- Infective Endocarditis Diagnosis and Management
- Intensive Care Unit Cognitive Disorders
- Cardiac Health and Mental Health
- Heart Failure Treatment and Management
- COVID-19 Clinical Research Studies
- COVID-19 and Mental Health
- Health and Medical Research Impacts
- Long-Term Effects of COVID-19
- Heart Rate Variability and Autonomic Control
- Pulmonary Hypertension Research and Treatments
Brown University
2016-2025
Providence College
2010-2024
Lifespan
2014-2024
John Brown University
2002-2024
Providence VA Medical Center
2002-2024
Rhode Island Hospital
2012-2022
Miriam Hospital
2017-2022
Newport Hospital
2020-2022
American College of Cardiology
2016-2021
Athena Group (United States)
2015-2021
The COVID-19 pandemic required a significant redeployment of worldwide healthcare resources. Fear infection, national lockdowns and altered priorities have the potential to impact utilisation resources for non-communicable diseases. To survey health professionals' views on rate timing admission patients with ST-elevation myocardial infarction (STEMI), European Society Cardiology (ESC) administered an internet-based questionnaire cardiologists cardiovascular nurses across 6 continents. 3101...
Temporal changes in systemic arterial compliance and wave propagation properties (pulsatile load) their role ventricular-systemic coupling during gestation have not been explored. Noninvasive methods combined with recently developed mathematical modeling techniques were used to characterize vascular left ventricular (LV) mechanical adaptations normal gestation.Fourteen healthy women studied at each trimester of pregnancy again postpartum. Experimental measurements included instantaneous...
Long QT syndrome (LQTS) is a heritable disease associated with ECG interval prolongation, ventricular tachycardia, and sudden cardiac death in young patients. Among genotyped individuals, mutations genes encoding repolarizing K+ channels (LQT1:KCNQ1; LQT2:KCNH2) are present approximately 90% of affected individuals. Expression pore mutants the human KCNQ1 (KvLQT1-Y315S) KCNH2 (HERG-G628S) rabbit heart produced transgenic rabbits long phenotype. Prolongations intervals action potential...
Background and Purpose- Left atrial enlargement has been shown to be associated with ischemic stroke, but the association embolic stroke mechanisms remains unknown. We aim study associations between left volume index (LAVI) subtypes fibrillation (AF) detection on cardiac event monitoring in patients of unknown source. Methods- Data were collected from a prospective cohort consecutive admitted comprehensive center over 18 months. Stroke subtype was classified into cardioembolic...
<h3>Importance</h3> There has been limited research on patients with ST-segment elevation myocardial infarction (STEMI) and COVID-19. <h3>Objective</h3> To compare characteristics, treatment, outcomes of STEMI vs without COVID-19 infection. <h3>Design, Setting, Participants</h3> Retrospective cohort study consecutive adult admitted between January 2019 December 2020 (end follow-up in 2021) out-of-hospital or in-hospital at 509 US centers the Vizient Clinical Database (N = 80 449)....
Background and Purpose— The presence of white matter hyperintensities on brain MRI is common among elderly individuals. Previous research suggests that cardiovascular risk factors are associated with increased hyperintensities. Examining the role direct physiological measures vascular function will help to clarify mechanisms related aim present study was examine association between endothelial-dependent endothelial-independent vasodilatation hyperintensity volume. Methods— Twenty-five older...
Several trials support the usefulness of disease management (DM) for improving clinical outcomes in heart failure (HF). Most these studies are limited by small sample size; absence concurrent, randomized controls; follow-up; restriction to urban academic centers; and low baseline use effective medications.We performed a prospective, assessment effectiveness HF DM delivered 90 days across diverse provider network heterogeneous population 200 patients with high approved pharmacotherapy. During...
To preliminarily examine the association between cardiac output, a measure of systemic blood flow, and structural brain magnetic resonance imaging indices white matter hyperintensities (WMHs).Cross-sectional.University medical setting.Thirty-six older adults without dementia with prevalent cardiovascular disease (aged 56-85).Cardiac WMHs.Partial correlations, adjusting for age history hypertension, yielded an inverse relationship WMHs adjacent to subcortical nuclei output (correlation...
This study examines the relationship between systemic vascular function, neurocognitive performance, and structural brain abnormalities on magnetic resonance imaging (MRI) among geriatric outpatients with treated, stable cardiovascular disease no history of neurological illness (n = 88, ages 56–85 years). Vascular function was assessed by cardiac ejection fraction output, sequential systolic diastolic blood pressures, flow mediated brachial artery reactivity (BAR), carotid intima media...
Objectives To characterize cognition in patients with moderate to severe heart failure and examine the association between 2 measures of systemic perfusion (ie, ejection fraction cardiac index) cognition. Background Decreased has been implicated as an etiologic factor development cognitive deficits cardiovascular disease. Method Thirty-one 31 disease no completed a medical history interview neuropsychologic assessment. Participants additionally underwent echocardiogram assess function....