A5072862594- Dementia and Cognitive Impairment Research
- Diet and metabolism studies
- Heart Failure Treatment and Management
- Cardiac Health and Mental Health
- Bariatric Surgery and Outcomes
- Blood Pressure and Hypertension Studies
- Traumatic Brain Injury Research
- Heart Rate Variability and Autonomic Control
- Intensive Care Unit Cognitive Disorders
- Cardiovascular and exercise physiology
- Nutritional Studies and Diet
- Obesity, Physical Activity, Diet
- Eating Disorders and Behaviors
- Cardiovascular Health and Disease Prevention
- Cerebrovascular and Carotid Artery Diseases
- Functional Brain Connectivity Studies
- Thermoregulation and physiological responses
- Attention Deficit Hyperactivity Disorder
- Regulation of Appetite and Obesity
- Sleep and related disorders
- Physical Activity and Health
- Cardiac, Anesthesia and Surgical Outcomes
- Nutrition and Health in Aging
- High Altitude and Hypoxia
- Neural and Behavioral Psychology Studies
Kent State University
2016-2025
National Heart Lung and Blood Institute
2021
Miriam Hospital
2021
Brown University
2003-2021
Providence College
2006-2021
Case Western Reserve University
2010-2021
Summa Health System
2007-2016
Boston University
2007-2016
National Institutes of Health
2016
VA Boston Healthcare System
2016
<i>Background:</i> Obesity indices (i.e. BMI, waist-to-hip ratio) show differential relationships to other health outcomes, though their association neurocognitive outcome is unclear. <i>Methods:</i> We examined whether central obesity would be more closely associated with cognitive function in 1,703 participants from the Baltimore Longitudinal Study of Aging. <i>Results:</i> mixed-effects regression models showed multiple were poorer performance a variety...
Existing work demonstrates that obesity is independently associated with cognitive dysfunction and macrostructural brain changes; however, little known about the association between white matter (WM) integrity. We explore this relationship in a large cohort of otherwise healthy subjects. The present study classified 103 adult participants from Brain Resource International Database 21 86 years age without history neurological, medical, or psychiatric illness according to BMI (normal weight,...
The present study examined the effect of negative expectations on neuropsychological test performance. It was hypothesized that having attention called to a history prior head injury and potential effects cognition would result in diminished performance relative individuals with similar but who did not have their (‘diagnosis threat’). Of 36 participants mild injury, 17 were randomly assigned diagnosis threat 19 neutral directions. group performed significantly worse tests measuring general...
There is a growing evidence that elevated body mass index (BMI) associated with adverse neurocognitive outcome, though no study has examined whether morphometric differences are found in persons across the adult life span. We compared 201 healthy individuals normal weight, overweight, and obese groups (aged 17-79). After correcting for demographic differences, showed smaller whole brain total gray matter volume than weight overweight individuals. These findings support an independent...
The purpose of this study was to examine the impact age, sex, and education on category letter verbal fluency task performance. A secondary goal whether resting EEG theta power in bilateral frontal temporal lobes impacts age-associated decline large sample (N=471) healthy, normal participants, age 21–82, assessed for (i.e., FAS), Animal Naming), with a 32-channel system 'eyes-open' power. effects were examined using analyses variance. Correlation used test performance by controlling when...
The present study explored the explanatory power of Mittenberg's “expectation as etiology” theory for persistence postconcussion syndrome (PCS) complaints. One hundred forty-one participants completed a PCS symptom checklist under 2 conditions. Normal controls, healthy athletes and depressed individuals reported current symptoms expected following hypothetical mild head injury. Head-injured athletes, chronic headache sufferers, 2nd sample normal controls retrospective (prior to their...
Cognitive decline is common in older adults, even the absence of significant medical or neurological conditions. Recent work implicates serum levels brain-derived neurotrophic factor age-related cognitive decline, though no study has directly examined this possibility. A total 35 adults without history underwent fasting blood draw and completed a brief neuropsychological test battery during single session. After adjusting for demographic confounds, higher were associated with better...
Objective Treatment recommendation and guidelines for patients with heart failure (HF) can be complex, past work has shown that HF demonstrate low rates of adherence to recommended health behaviors. Although previous identified several medical, demographic, psychosocial predictors the capacity adhere treatment recommendations persons HF, little is known about contribution cognitive impairment reported in this population. Methods A total 149 (mean [standard deviation] = 68.08 [10.74] years)...
Cognitive impairment is common in heart failure ( HF ) and believed to be the result of cerebral hypoperfusion subsequent brain changes including white matter hyperintensities WMHs ). The current study examined association between blood flow patients with relationship cognitive impairment. Sixty‐nine completed Mini‐Mental State Examination MMSE underwent echocardiography, transcranial Doppler sonography for velocity middle artery, magnetic resonance imaging. Multivariable hierarchical...
Obesity is as an independent risk factor for poor neurocognitive outcomes, including Alzheimer's disease. Bariatric surgery has recently been shown to result in improved memory at 12-weeks postoperatively. However, the long-term effects of bariatric on cognitive function remain unclear.Eighty-six individuals (63 patients, 23 obese controls) were recruited from a prospective study examining surgery. All participants completed self-report measurements and computerized test battery prior...
Obesity is associated with cognitive dysfunction in children and adolescents, although the mechanisms underlying these deficits remain unclear. This study examined associations between body mass index (BMI) regional gray matter volume white integrity 120 healthy adolescents (6–18 years of age) who underwent magnetic resonance diffusion tensor imaging. Bonferroni-corrected partial correlation analyses controlling for demographic clinical characteristics revealed significant inverse...
AbstractObjective: Sports-related concussions are associated with both acute and long-term consequences. Past work has identified novel risk factors modifiers for concussions, including mood neuropsychiatric disorders. Attention Deficit Hyperactivity Disorder (ADHD) is a common disorder that may also contribute to concussion risk, although no study examined this possibility.Methods: One hundred thirty-nine NCAA Division-I athletes at Kent State University (KSU) self-reported history of prior...
Abstract Objectives: Dysbiosis of the gut microbiome is implicated in numerous human health conditions. Animal studies have linked disruption to changes cognitive functioning, although no study has examined this possibility neurologically healthy older adults. Methods: Participants were 43 community-dwelling adults (50–85 years) that completed a brief test battery and provided stool samples for sequencing. performing≥1 SD below normative performance on two or more tests compared persons with...