A5001839243- Schizophrenia research and treatment
- Mental Health and Psychiatry
- Child and Adolescent Psychosocial and Emotional Development
- Psychosomatic Disorders and Their Treatments
- Mental Health Research Topics
- Effects of Radiation Exposure
- Functional Brain Connectivity Studies
- Mental Health Treatment and Access
- Bipolar Disorder and Treatment
- Facial Trauma and Fracture Management
- Psychiatric care and mental health services
- Craniofacial Disorders and Treatments
- Medical and Biological Sciences
- Pulsars and Gravitational Waves Research
- Health and Medical Studies
- Reproductive Biology and Fertility
- Advanced Neuroimaging Techniques and Applications
- Personality Disorders and Psychopathology
- Obsessive-Compulsive Spectrum Disorders
- Neural dynamics and brain function
- Radiation Dose and Imaging
- Tryptophan and brain disorders
- Cleft Lip and Palate Research
- Organ and Tissue Transplantation Research
- Neurological disorders and treatments
University of Bern
2016-2025
Institute of Nuclear Physics of Lyon
2020-2025
Institut de Physique des 2 Infinis de Lyon
2020-2025
Laboratoire des Matériaux Avancés
2009-2024
Institut de Radioprotection et de Sûreté Nucléaire
2013-2023
University of Geneva
2016-2023
Université Claude Bernard Lyon 1
2007-2021
Institut National de Physique Nucléaire et de Physique des Particules
2010-2021
Centre National de la Recherche Scientifique
2007-2021
Universitätsklinik für Kinder und Jugendpsychiatrie
2020
Diverse models have been developed to predict psychosis in patients with clinical high-risk (CHR) states. Whether prediction can be improved by efficiently combining and biological broadening the risk spectrum young depressive syndromes remains unclear.To evaluate whether transition predicted CHR or recent-onset depression (ROD) using multimodal machine learning that optimally integrates neurocognitive data, structural magnetic resonance imaging (sMRI), polygenic scores (PRS) for...
Early detection of psychosis is an important topic in psychiatry. Yet, there limited information on the prevalence and clinical significance high-risk symptoms children adolescents as compared to adults. We examined ultra-high-risk (UHR) criteria a sample individuals aged 8-40 years from general population Canton Bern, Switzerland, enrolled June 2011 May 2014. The current presence attenuated psychotic (APS) brief intermittent (BLIPS) fulfillment onset/worsening frequency requirements for...
Section III of the Diagnostic and Statistical Manual Mental Disorders, Fifth Edition (DSM-5) lists attenuated psychosis syndrome as a condition for further study. One important question is its prevalence clinical significance in general population.
[Correction Notice: An Erratum for this article was reported in Vol 125(7) of Journal Abnormal Psychology (see record 2016-47529-004). In the article, there an error Author Note. The affiliation Daniela Hubl incorrectly listed as "University Hospital Child and Adolescent Psychiatry Psychotherapy, University Bern." It should have been All versions corrected.] Schizotypy is considered indicator psychosis-proneness therefore, a precursor to schizophrenia-spectrum psychosis. early detection...
Impaired cognition is an important dimension in psychosis and its at-risk states. Research on the value of impaired for prediction samples, however, mainly relies study-specific sample means neurocognitive tests, which unlike widely available general test norms are difficult to translate into clinical practice. The aim this study was explore combined predictive criteria deficits according with a risk stratification approach.Potential predictors (neurocognitive criteria) over 24 months were...
An efficient indicated prevention of psychotic disorders requires valid risk criteria that work in both clinical and community samples. Yet, ultra-high basic symptom were recently recommended for use samples only. Their the was discouraged lack knowledge about their prevalence, relevance factors non-clinical, settings when validly assessed with same instruments used clinic.Using semi-structured telephone interviews established psychosis-risk instruments, we studied prevalence symptoms...
Abstract Aims Clinical high-risk for psychosis (CHR-P) states exhibit diverse clinical presentations, prompting a shift towards broader outcome assessments beyond manifestation. To elucidate more uniform profiles and their trajectories, we investigated CHR-P in community sample. Methods Participants ( N = 829; baseline age: 16–40 years) comprised individuals from Swiss sample who were followed up over roughly 3 years. latent class analysis was applied to symptom data at follow-up, classes...
Abstract Background Beyond psychosis prediction, clinical high-risk (CHR-P) symptoms show relevance by their association with functional impairments and psychopathology, including personality pathology. Impaired functioning is prioritized in recent dimensional disorder models (DSM-5, ICD-11), yet underexplored CHR-P, as are associations cognitive biases, which early studies indicate possibly linking CHR-P-symptoms Methods A community sample ( N = 444, 17–60 years, 61.8% female) was assessed...
Abstract Background This study aimed to deepen the understanding of psychological mechanisms underlying formation and maintenance clinical high-risk symptoms for psychosis (CHR-P) in real-life contexts. Specifically, it examined whether (i) momentary feelings stress increase frequency CHR-P symptoms, or conversely, (ii) intensity stress. Additionally, potential moderators relationship between were explored. Methods Using Ecological Momentary Assessment, 79 patients (age: 11–36; 50.6% female)...
Abstract Aim: The Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Cluster A personality disorders (PDs), particularly schizotypal PD, are considered a part the schizophrenia spectrum risk factor psychosis. role PDs accentuations (PAs) in predicting conversion to psychosis was studied patients symptomatically at risk, assuming major subtype. Methods: PAs, assessed baseline with self‐report questionnaire, were compared between risk‐, gender‐ age‐matched at‐risk ( n = 50)...