A5047150310- High-Energy Particle Collisions Research
- Particle physics theoretical and experimental studies
- Nuclear physics research studies
- Quantum Chromodynamics and Particle Interactions
- Stochastic processes and statistical mechanics
- Theoretical and Computational Physics
- Statistical Mechanics and Entropy
- Complex Systems and Time Series Analysis
- Monoclonal and Polyclonal Antibodies Research
- Scientific Research and Discoveries
- Neuroinflammation and Neurodegeneration Mechanisms
- RNA Research and Splicing
- Neural Networks and Applications
- Neuropeptides and Animal Physiology
- Receptor Mechanisms and Signaling
- Viral Infectious Diseases and Gene Expression in Insects
- Advanced Biosensing Techniques and Applications
- Atmospheric chemistry and aerosols
- RNA modifications and cancer
- Fractal and DNA sequence analysis
- Reproductive System and Pregnancy
- Nuclear reactor physics and engineering
- Atmospheric Ozone and Climate
- Music and Audio Processing
- Neuroscience and Music Perception
Saraswati Dental College and Hospital
2024
Centre of Biomedical Research
2020-2023
Sanjay Gandhi Post Graduate Institute of Medical Sciences
2020-2023
Jadavpur University
2004-2021
Dr. C. V. Raman University
2021
Johns Hopkins University
2001-2020
Johns Hopkins Medicine
2013-2019
High Throughput Biology (United States)
2018
H. L. Snyder Medical Foundation
2017
All India Institute of Medical Sciences
2007-2009
Abstract Public archives of next-generation sequencing data are growing exponentially, but the difficulty marshaling this has led to its underutilization by scientists. Here, we present ASCOT, a resource that uses annotation-free methods rapidly analyze and visualize splice variants across tens thousands bulk single-cell sets in public archive. To demonstrate utility identify novel cell type-specific alternative exons nervous system leverage ENCODE GTEx study unique splicing photoreceptors....
Significance Misincorporation of dUTP into DNA is detrimental to eukaryotes, prokaryotes, and viruses. This study reveals the fate uracilated HIV-1 in human cells. Early stages viral life cycle are unaffected, but integration host genome prevented. effect wholly dependent on presence UNG2, a nuclear enzyme that excises uracil from DNA. establishes UNG2 restriction factor for explains why this pathway not fully engaged CD4+ T cells macrophages.
Our present knowledge about trophoblast turnover in human first trimester placental villi based on multiparametric examination of proliferation and apoptosis is limited.Human villous placentae collected during 6, 7 8 weeks (n = 10/each group) gestation were examined for quantitative analyses immunopositive Fas, tumor necrosis factor receptor 1 (TNFR1), cytokeratin 18 fragment (18f), number proliferating cell nuclear antigen (PCNA), Ki67 terminal deoxynucleotidyl transferase-mediated dUTP...
Tanpura is a multi-stringed accompanying drone instrument extensively used in classical music India. The plucked by finger. We know that jitter, shimmer and complexity perturbations (CP) are found also tanpura signals. source of origin these was reported to be related some sort nonlinearity associated with the strings their mode attachment. objective present study see what way fractal-dimensional analysis may helpful relate apparent if there any relation dimensions different part signals...
Abstract Human G protein-coupled receptors (GPCRs) respond to various ligands and stimuli. However, GPCRs rely on membrane for proper folding, making their biochemical properties difficult study. By displaying in viral envelopes, we fabricated a Virion Display (VirD) array containing 315 non-olfactory human functional characterization. Using this array, found that 10 of 20 anti-GPCR mAbs were ultra-specific. We further demonstrated those failed the mAb assays could recognize canonical...
Introduction: Mitophagy, the selective degradation of damaged mitochondria, is essential for maintaining cellular health and function, particularly in high-energy demanding post-mitotic cells like neurons microglial cells. Aging results impaired mitophagy, leading to mitochondrial dysfunction, oxidative stress, release damage-associated proteins (DAMPs), neuroinflammation, which contribute neurodegenerative diseases such as Alzheimer’s Parkinson’s. Mitochondrial dysfunction also contributes...
Progesterone is essential for endometrial receptivity in primates. In studies previously performed using global gene profiling based on microarray technology, attempts have been made to identify changes expression between early luteal-phase and mid-luteal-phase endometria. However, the issue of putative impact preimplantation embryo-derived signal process was missing previous studies. present study, an attempt has delineate transcripts profile implantation-stage endometrium under...
This work studies the validity of negative binomial distribution in multiplicity charged secondaries 16O and 32S interactions with AgBr at 60 GeV/c per nucleon 200 nucleon, respectively. The (NBD) is studied different azimuthal phase spaces. It observed that data can be well parameterized terms NBD law for
The sitar is perhaps the most well known of Indian plucked string musical instruments. It has a varying number strings but 16–20 usual. When played by an expert, produces melodious sound effect. mode attachment and or interaction large strings, some them being playing drone others sympathetic, create total acoustic environment, which also includes global resonance structure instrument. This creates whose complexity difficult to model usual mathematical methods. Fractal dimension effective...
The fractal behaviour of medium-energy knocked-out protons in angular and azimuthal phase space for 28Si-AgBr interactions at 14.5 A GeV has been studied using Takagi's method. generalized dimensions (Dq) are determined from this data reflects the monofractal protons.
An investigation of non-statistical fluctuation the compound multiplicity spectrum in 32S–AgBr interactions at 200 AGeV terms factorial correlators is presented. It observed that correlated moments increase with decrease bin–bin separation D, following a power law, which suggests presence an intermittent nature self-similar dynamical patterns spectrum. The data also support α model intermittency.
The authors present a study of the transverse momentum distribution relativistic alpha particles emerging from interaction 12C and emulsion at 4.5 GeV/c per nucleon. A large statistics 1200 events when compared with Maxwell-Boltzmann reveals existence two temperatures, hot cold, since single cannot fit peak tail simultaneously. This yield distinctly different temperatures in fragmentation region may be interpreted as possible signal for formation quark-gluon plasma.
The paper reports a study revealing self-affine fluctuations in pion, proton, and compound multiplicity (of pions combined with protons) spectra obtained from the interactions of 350 GeV AgBr nuclei. is performed transformed two-dimensional phase space emission azimuthal angles using factorial moment methodology concept Hurst exponent. Evidence nonthermal transition for along an indication such regime to be seen similar proton distributions. bridges anisotropic nature multiparticle...
Abstract Indeterminacy in music, a well known neo-avant-garde approach of composing sound where some features musical work are left open to chance or the interpreter’s free choice, became noticeable among American music composers such as John Cage, Earle Brown, Morton Feldman and Christian Wolff mid 20th century. Simultaneously, group artists from West created “abstract expressionism” visual arts, which showed strong resemblance with this “indeterminate music”, both using two kinds abstract...