A5045169513- Nanoparticle-Based Drug Delivery
- Nanoplatforms for cancer theranostics
- Microfluidic and Bio-sensing Technologies
- 3D Printing in Biomedical Research
- Cell Adhesion Molecules Research
- Microfluidic and Capillary Electrophoresis Applications
- Advanced Nanomaterials in Catalysis
- Photoacoustic and Ultrasonic Imaging
- Cerebrovascular and Carotid Artery Diseases
- Cardiac Imaging and Diagnostics
- Biochemical and Structural Characterization
- Advanced biosensing and bioanalysis techniques
- Monoclonal and Polyclonal Antibodies Research
- Hydrogels: synthesis, properties, applications
- Peptidase Inhibition and Analysis
- Polymer Surface Interaction Studies
- Electrospun Nanofibers in Biomedical Applications
- Blood properties and coagulation
- Extracellular vesicles in disease
- Advanced Drug Delivery Systems
- Nanoparticles: synthesis and applications
- Characterization and Applications of Magnetic Nanoparticles
- Protease and Inhibitor Mechanisms
- Glycosylation and Glycoproteins Research
- Innovative Microfluidic and Catalytic Techniques Innovation
Griffith University
2020-2025
The University of Queensland
2014-2024
University of Oulu
2021
Australian Research Council
2019
Princess Alexandra Hospital
2019
Brisbane School of Theology
2018
Baker Heart and Diabetes Institute
2010-2018
Tianjin Beichen Hospital
2013
Monash University
2011
University Medical Center Freiburg
2011
Two important challenges in the field of 19F magnetic resonance imaging (MRI) are maintenance high fluorine content without compromising performance, and effective targeting small particles to diseased tissue. To address these challenges, we have developed a series perfluoropolyether (PFPE)-based hyperbranched (HBPFPE) nanoparticles with attached peptide aptamer as ligands for specific vivo detection breast cancer MRI sensitivity. A detailed comparison HBPFPE (NPs) previously reported...
Fluorine-containing polymeric materials are receiving increasing attention as imaging probes in fluorine-19 magnetic resonance (19F MRI), for example to enable quantitative vivo detection of cells. Here we describe the one-pot polymerization synthesis 19F-containing functional poly(oligo(ethylene glycol) methyl ether methacrylate-co-2,2,2-trifluoroethyl acrylate-b-poly(styrene-co-3-vinylbenzaldehyde) (poly(OEGA-co-TFEA)-b-poly(St-co-VBA)) copolymers a new class fluorinated MRI agent. A range...
Abstract Responsive nanoprobes play an important role in bioassay and bioimaging, early diagnosis of diseases treatment monitoring. Herein, a upconversional nanoparticle (UCNP)‐based nanoprobe, Ru@UCNPs, for specific sensing imaging hypochlorous acid (HOCl) is reported. This Ru@UCNP nanoprobe consists two functional components,, i.e., NaYF 4 :Yb, Tm UCNPs that can convert near infrared light‐to‐visible light as the energy donor, HOCl‐responsive ruthenium(II) complex [Ru(bpy) 2 (DNCH‐bpy)](PF...
Abstract Thrombosis and its complications are responsible for 30% of annual deaths. Limitations methods diagnosing treating thrombosis highlight the need improvements. Agents that provide simultaneous diagnostic therapeutic activities (theranostics) paramount an accurate diagnosis rapid treatment. In this study, silver‐iron oxide nanoparticles (AgIONPs) developed highly efficient targeted photothermal therapy imaging thrombosis. Small iron employed as seeding agents generation a new class...
Antibody-targeted delivery of imaging agents can enhance the sensitivity and accuracy current techniques. Similarly, homing effector cells to disease sites increases efficacy regenerative cell therapy while reducing number required. Currently, targeting be achieved via chemical conjugation specific antibodies, which typically results in loss antibody functionality severe damage. An ideal technique should ensure retention antigen-binding activity targeted biological component.To develop a...
Reactive oxygen species (ROS) and reactive nitrogen (RNS) are key signaling molecules that play an important role in the inflammation progression of many diseases such as cardiovascular disease, especially atherosclerosis. ROS particular a significant factor development rheumatoid arthritis other autoimmune allergies. In this study, novel Fe3O4/CeO2 core-shell theranostic nanoparticles capable reacting with being detected by MRI were synthesized thoroughly characterized. vitro studies,...