Sarah B. Nossov

ORCID: 0000-0003-1191-074X
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About
Contact & Profiles
Research Areas
  • Bone fractures and treatments
  • Orthopaedic implants and arthroplasty
  • Hip disorders and treatments
  • Scoliosis diagnosis and treatment
  • Diversity and Career in Medicine
  • Cerebral Palsy and Movement Disorders
  • Congenital Diaphragmatic Hernia Studies
  • Musculoskeletal Disorders and Rehabilitation
  • Child and Adolescent Health
  • Neurogenetic and Muscular Disorders Research
  • Total Knee Arthroplasty Outcomes
  • Orthopedic Surgery and Rehabilitation
  • Spinal Fractures and Fixation Techniques
  • Shoulder and Clavicle Injuries
  • Parvovirus B19 Infection Studies
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Respiratory Support and Mechanisms
  • Shoulder Injury and Treatment
  • Pelvic and Acetabular Injuries
  • Apelin-related biomedical research
  • Elbow and Forearm Trauma Treatment
  • Family and Patient Care in Intensive Care Units
  • Blood Coagulation and Thrombosis Mechanisms
  • Pleural and Pulmonary Diseases
  • Hip and Femur Fractures

Shriners Hospitals for Children - Philadelphia
2017-2024

Cardinal Glennon Children’s Medical Center
2024

Rothman Orthopaedics
2024

Orthopedic Institute
2024

SUNY Downstate Health Sciences University
2024

Shriners Hospitals for Children Medical Center - Lexington
2023

Porter Adventist Hospital
2022

Temple University
2022

Shriners Hospitals for Children - Erie
2017

University of Michigan
2014-2016

An insertion polymorphism of the angiotensin-I converting enzyme gene ( ACE ) is common in humans and higher expressing allele associated with an increased risk diabetic complications. The does not significantly affect blood pressure or angiotensin II levels, suggesting that kallikrein-kinin system partly mediates effects polymorphism. We have therefore explored influence lack both bradykinin receptors (B1R B2R) on nephropathy, neuropathy, osteopathy male mice heterozygous for Akita...

10.1073/pnas.1005144107 article EN Proceedings of the National Academy of Sciences 2010-05-17

Background: The management of pediatric type I open fractures remains controversial. aim this study is to compare outcomes in managed with superficial wound debridement and antibiotics the emergency department (ED) (nonoperative management) patients operative (operative management). Methods: A multicenter retrospective review was performed all forearm, wrist, tibia treated at 4 high volume centers between 2000 2015. Patients multiple traumatic injuries, immunocompromised patients, or those...

10.1097/bpo.0000000000000972 article EN Journal of Pediatric Orthopaedics 2017-03-11

The assisted ventilation rating (AVR) indicates the degree of external respiratory support required in children with thoracic insufficiency syndrome (TIS) and early onset scoliosis. For skeletally immature patients TIS, vertical expandable prosthetic titanium rib (VEPTR) device can be used to improve lung volume growth. We hypothesized that who underwent reconstruction by VEPTR treatment had an improved status.Preoperative postoperative AVR ratings were prospectively collected a multicenter...

10.1097/bpo.0000000000000986 article EN Journal of Pediatric Orthopaedics 2017-04-11

Purpose: Arthrogryposis multiplex congenita (AMC) consists of more than 400 conditions involving severe joint contractures at least two or body regions. Management clubfoot in patients with AMC is notoriously challenging, a higher likelihood recurrence idiopathic clubfoot, which can be treated using the Ponseti technique to avoid delay invasive procedures. The purpose this study determine utility multiple serial casting as treatment Pirani scores an objective measure deformity. Methods: were...

10.7759/cureus.54398 article EN Cureus 2024-02-18

Proximal focal femoral deficiency is a congenital transverse in which the femur globally smaller with typical proximal deformity at hip that may include distal involvement of knees, leg, and feet. Congenital (CFD) describes broader spectrum longitudinal inclusive deficiency. CFD also lateral hypoplasia, knee cruciate ligament deficiency, rotational instability, patellar dislocation, fibular hemimelia, ray absence, contralateral limb involvement. Treatment intends to maximize function by...

10.5435/jaaos-d-21-01186 article EN Journal of the American Academy of Orthopaedic Surgeons 2022-04-28

Abstract Background Classification of the spinal deformity in adolescent idiopathic scoliosis (AIS) remains two-dimensional (2D) as radiographs remain mainstay clinical evaluation disease. 3D classification systems are proposed, however time consuming. We here aim to evaluate application a system by use only posterior-anterior and lateral Lenke 1 (AIS). Methods Forty AIS were classified five observers following three-step flowchart, developed based on our previous system. This characterizes...

10.1186/s12891-020-03798-x article EN cc-by BMC Musculoskeletal Disorders 2020-12-01

Tension band plate and screw implants (TBI) are frequently used for temporary hemiepiphyseodeses to manage angular deformity in growing children. The reported implant breakage rate, when TBI is deformities patients with Blount disease, much higher than other diagnoses. Our hypothesis that perioperative factors can identify risks breakage.A retrospective case-control study was performed of 246 procedures 113 disease at 8 tertiary pediatric orthopaedic centers from 2008 2018. Patient...

10.1097/bpo.0000000000002103 article EN Journal of Pediatric Orthopaedics 2022-02-24

The Pediatric Orthopaedic Society of North America (POSNA) is excited to celebrate 50 years the subspecialty pediatric orthopaedic surgery in America.  In 1996, Dr. Hugh Watts, POSNA historian from 1992-1999, wrote a very detailed and personal account first 25 societies (1971-1996).  current members History & Archives Committee have sought expand on this historical account, with notable updates past (1996-2021).  These highlights are certainly not comprehensive, but seek...

10.55275/jposna-2022-0040 article EN cc-by-nc-nd Journal of the Pediatric Orthopaedic Society of North America 2022-05-01

Background: Despite early osteotomy, many patients with infantile tibia vara (ITV) have persistent or recurrent varus deformity and disordered growth at the medial proximal tibial physis. Our hypothesis was that lateral tension band plating (LTTBP) could guide correction. Methods: A retrospective review 6 centers of 15 (16 extremities) performed LTTBP for following osteotomy in ITV, diagnosed≤4years age. Correction parameters on digital standing anteroposterior lower extremity radiographs...

10.1097/bpo.0000000000002238 article EN Journal of Pediatric Orthopaedics 2022-08-16

While tibia vara is a disorder of the proximal tibial physis, femoral deformity frequently contributes to overall limb malalignment. Our purpose was determine how varus in responds growth modulation, with/without lateral tension band plating (LTBP) femur.One-hundred twenty-seven limbs undergoing LTBP for were reviewed. All had and 35 also varus. Radiographs measured correction mechanical distal angle (mLDFA) axis deviation (MAD). Preoperative-femoral defined with an age-adjusted guide: mLDFA...

10.1097/bpo.0000000000002358 article EN Journal of Pediatric Orthopaedics 2023-02-15

Growth modulation in late-onset tibia vara (LOTV) has been reported to yield variable results. We hypothesized that parameters of deformity severity, skeletal maturity, and body weight could predict the odds a successful outcome.A retrospective review tension band growth for LOTV (onset ≥8 y) was performed at 7 centers. Tibial/overall limb hip/knee physeal maturity were assessed on preoperative anteroposterior standing lower-extremity digital radiographs. Tibial change with first-time...

10.1097/bpo.0000000000002373 article EN Journal of Pediatric Orthopaedics 2023-03-13

Angular deformity correction with tension band plating has not been as successful in early-onset tibia vara (EOTV) it other conditions. Our hypothesis is that perioperative factors can predict the success of lateral tibial (LTTBP) patients EOTV.A retrospective review was performed at 7 centers evaluating radiographic outcomes LTTBP EOTV (onset <7 y age). Single-event outcome assessed through medial proximal angle (MPTA). The final limb alignment following comprehensive growth modulation...

10.1097/bpo.0000000000002375 article EN Journal of Pediatric Orthopaedics 2023-03-24

An argument could be made that the most recognized name in history of pediatric orthopaedics belongs to Dr. Robert Salter. Every medical student last 50 years has at least heard his classification growth plate injuries and have been tested on it. His innovations contributions are numerous stood test time. In 2020, Journal Orthopaedics listed impactful orthopaedic literature, Salter’s is cited 56 top 100 referenced papers. As time passes, impact remain. Yet who was this man? What him a legend...

10.55275/jposna-2023-746 article EN cc-by-nc-nd Journal of the Pediatric Orthopaedic Society of North America 2023-08-01
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