A5038684763- Mesenchymal stem cell research
- Tree Root and Stability Studies
- Bone health and treatments
- Orthopaedic implants and arthroplasty
- Bone fractures and treatments
- Bone and Dental Protein Studies
- Crop Yield and Soil Fertility
- Biomedical and Engineering Education
- Engineering Education and Curriculum Development
- S100 Proteins and Annexins
- Engineering Education and Pedagogy
- Polysaccharides and Plant Cell Walls
- Bamboo properties and applications
- TGF-β signaling in diseases
- Dynamics and Control of Mechanical Systems
- Blood groups and transfusion
- Bone health and osteoporosis research
- Blood properties and coagulation
- Connective tissue disorders research
- Mechanics and Biomechanics Studies
- Soil Mechanics and Vehicle Dynamics
- Erythrocyte Function and Pathophysiology
- Bone Metabolism and Diseases
- Total Knee Arthroplasty Outcomes
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
University of Mount Union
2024
New York University Abu Dhabi
2017-2018
Hashemite University
2010-2013
Rutgers, The State University of New Jersey
2008-2012
Rutgers New Jersey Medical School
2008-2012
New Jersey Institute of Technology
2009-2010
Abstract Diabetes mellitus is a common systemic disease that has been associated with poor fracture healing outcomes. The mechanism through which diabetes impairs bone regeneration unknown. One possible may be related to either decreased or uncoordinated release of local growth factors at the site. Indeed, previous studies have found reduced platelet‐derived factor (PDGF) levels in callus diabetic rats, suggesting application PDGF overcome negative effects and promote healing. To test this...
Stalk lodging is a serious challenge in the production of maize and sorghum. A comprehensive understanding will likely require accurate characterizations mechanical properties such plants. One most important for structural analysis bending modulus elasticity. The purpose this study was to measure elasticity dry, mature rind tissues using three different loading modes (bending, compression tensile), determine accuracy reliability each test method.The testing produced comparable elastic...
The compressional modulus of elasticity is an important mechanical property for understanding stalk lodging, but this rarely available thin-walled plant stems such as maize and sorghum because excised tissue samples from these plants are highly susceptible to buckling. purpose study was develop a testing protocol that provides accurate reliable measurements the compressive rind pith-filled stems. general approach relying upon standard methods practices much possible, while developing new...
Objective: Recombinant human bone morphogenetic protein-2 (rhBMP-2) has been shown to enhance new formation in fracture and defect models both normal diabetic rats. Effects of rhBMP-2 a segmental femoral model diabetes mellitus (DM) BB Wistar rats have not reported. Methods: Collagen sponge soaked with either buffer or was inserted mid-diaphyseal 3.0-mm fixed polyimide plate stainless steel screws, 62 DM Progress the monitored serial radiographs every 2 weeks. Histomorphometric analysis done...
Allograft (Allo) incorporation in the presence of a systemic disease like diabetes mellitus (DM) is becoming major issue orthopedic community. Mesenchymal stem cells (MSC) are multipotent that may be derived from adult, whole bone marrow and have been shown to induce formation segmental defects when combined with appropriate carrier/scaffold. The objectives this study were analyze effect DM upon Allo rat femoral defect also investigate MSC augmentation incorporation. Segmental (5 mm) created...
Abstract Local insulin delivery has been shown to improve osseous healing in diabetic animals. The purpose of this study was quantify the effects local intramedullary saline or Ultralente (UL) on various fracture parameters using an vivo non‐diabetic BB Wistar rat model. Quantitation levels showed a rapid release from fractured femora, demonstrating complete at 2 days. RT‐PCR analysis revealed that expression early osteogenic markers (Col1α2, osteopontin) significantly enhanced with UL...
Abstract A significant number of lower extremity fractures result in mal‐union necessitating effective treatments to restore ambulation. Prior research diabetic animal fracture models demonstrated improved healing following local insulin application the site and indicated that therapy can aid bone regeneration, at least within an insulin‐dependent model. This study tested whether could accelerate femur repair normal, non‐diabetic rats. High (20 units) low (10 doses were delivered a calcium...
Despite the recapitulative nature of bone, a large percentage nonunions still occur. Many exogenous substances have been administered to aid in arthrodesis process, yet few proven efficacious relative time and cost. With recent advancements bone biology involving cellular molecular signaling, it is now possible selectively retain progenitor cells from patient's marrow. The commercially available product, CellectTM Cellect selective cell retention device has gained attention for its fast...
Abstract Work in Progress: A New Undergraduate Biomedical Engineering Program : An Innovative a Liberal Arts Institution Abstract: This paper describes new biomedical engineering undergraduate program at small liberal arts institution. The development of the was initiated by comprehensive feasibility report made 2016 that included assessment growth bioscience industry, cohesion with existing programs institution, potential students, and current trends future needs. curriculum provides depth...
Abstract Work in Progress: Clinical Immersion Model for Biomedical Engineering Undergraduate Students with Experienced Nurses Key words: Engineering, Nursing, Immersion, Design and Development Loay Al-Zube, Sara Dorris Abstract: The first phase the product design development process is need identification. There are many factors that can affect biomedical engineers' readiness ability to identify healthcare providers' clinical needs. Some of these include age, maturity, prior experience...
Abstract Engineers have the ability and responsibility to design develop solutions that can improve people's lives, solve pressing problems, make world a better place. Real-world challenges are becoming increasingly complex global, engineering projects often require collaboration between people from different cultures. Global is general course required by all students. The focuses on designing developing real-world problems in global context. In spring 2024, was offered an innovative way,...
A two dimensional three segments coupled pendulum system that mathematically models human arm configuration was developed along with constructing and solving the equations of motions for this model using energy (work) based approach Lagrange. The motion were solved iteratively both as an initial value problem a point boundary problem. In solutions, (segment angles) velocity angular velocities) used inputs, whereas, in solutions final configurations time inputs to solve trajectory motion....
Normalization of blood glucose levels with systemic insulin or by local administration to the fracture site can normalize early parameters healing. However, short biological half-lives growth factors and cytokines may impose severe restraints on their clinical usefulness. To find an optimal carrier, calcium salts (Calcium sulfate (CaSO 4 ) β-tricalcium phosphate (TCP)) have been investigated as possible delivery vehicles for in osseous repair. Released kinetics was determined both materials...