James S. Khan

ORCID: 0000-0003-1210-7545
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About
Contact & Profiles
Research Areas
  • Anesthesia and Pain Management
  • Cardiac, Anesthesia and Surgical Outcomes
  • Musculoskeletal pain and rehabilitation
  • Pain Management and Opioid Use
  • Pediatric Pain Management Techniques
  • Spine and Intervertebral Disc Pathology
  • Hemodynamic Monitoring and Therapy
  • Pain Mechanisms and Treatments
  • Pain Management and Placebo Effect
  • Health and Medical Research Impacts
  • Hip and Femur Fractures
  • Cardiac Health and Mental Health
  • Shoulder Injury and Treatment
  • Nerve Injury and Rehabilitation
  • Non-Invasive Vital Sign Monitoring
  • Anesthesia and Sedative Agents
  • Acupuncture Treatment Research Studies
  • Diversity and Career in Medicine
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Heart Rate Variability and Autonomic Control
  • Nausea and vomiting management
  • Pain Management and Treatment
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Botulinum Toxin and Related Neurological Disorders
  • Cancer survivorship and care

University of Toronto
2016-2025

Mount Sinai Hospital
2019-2025

Sinai Health System
2023-2024

University of California, San Francisco
2024

University Health Network
2014-2023

National Hospital for Neurology and Neurosurgery
2021

University College London
2021

McMaster University
2014-2019

Population Health Research Institute
2014-2019

Impact
2019

Tobacco smoking is associated with adverse health effects, and its relationship to pain complex. The longitudinal effect of on patients attending a tertiary management center not well established. Using the Collaborative Health Outcomes Information Registry Stanford Pain Management Center from 2013 2017, we conducted propensity-weighted analysis determine independent effects chronic pain. We adjusted for covariates including age, sex, body mass index, depression anxiety history, ethnicity,...

10.1097/j.pain.0000000000001631 article EN Pain 2019-05-28

Perioperative hypotension is associated with cardiovascular events in patients having noncardiac surgery. It unknown if the severity of preexisting coronary artery disease determines susceptibility to risks perioperative hypotension.In this retrospective exploratory analysis a substudy an international prospective blinded cohort study, 955 45 yr age or older history risk factors for underwent computed tomographic angiography before elective inpatient The authors evaluated potential...

10.1097/aln.0000000000002654 article EN Anesthesiology 2019-03-17

Chronic postsurgical pain is a common complication of surgery. The role psychologic risk factors like depression and anxiety substantially understudied in cardiac This study sought to identify perioperative associated with chronic at 3, 6, 12 months after authors hypothesize that baseline vulnerabilities have negative influence on pain.The prospectively collected demographic, psychologic, cohort 1,059 patients undergoing surgery the Toronto General Hospital between 2012 2020. Patients were...

10.1097/aln.0000000000004621 article EN Anesthesiology 2023-05-16

Objective Four sets of eight audible alarms matching the functions specified in IEC 60601-1-8 were designed using known principles from auditory cognition with intention that they would be more recognizable and localizable than those currently standard. Background The associated 60601-1-8, a global medical device standard, are to difficult learn retain, there have been many calls update them. There design might form basis readily alarms. is also scope for improvement localizability existing...

10.1177/0018720817712004 article EN Human Factors The Journal of the Human Factors and Ergonomics Society 2017-06-02

Background The purpose of this study was to determine the incidence, characteristics, impact, and risk factors associated with persistent incisional pain. hypothesis that patient demographics perioperative interventions are Methods This a secondary analysis an international prospective cohort from 2012 2014. included patients who were 45 yr age or older underwent major inpatient noncardiac surgery. Data collected perioperatively at 1 after surgery assess for development pain (pain present...

10.1097/aln.0000000000003951 article EN Anesthesiology 2021-09-09
Kyle Gouveia Sheila Sprague Jodi Gallant Gina Del Fabbro Jordan Leonard and 95 more Sofia Bzovsky Paula McKay Jason W. Busse Mohit Bhandari Gerard P. Slobogean Lehana Thabane Randi E. McCabe Emil H. Schemitsch Gordon Guyatt P.J. Devereaux Ida Leah Gitajn Matilda E. Nowakowski Eleni G. Hapidou Delia Chiaramonte Henrick Kehlet James S. Khan Aresh Sepehri Natalie Fleming Christy Shibu Diane Heels‐Ansdell Brad Petrisor Dale Williams Bill Ristevski Jamal Al-Asiri Herman Johal Matthew Denkers Kris Rajaratnam Sarah MacRae Kaitlyn Pusztai Sara Renaud Nicki Johal Steven Papp Karl‐André Lalonde Bradley Meulenkamp Allan Liew Manisha Mistry Braden Gammon Wade Gofton Geoffrey Wilkin Melanie Dodd-Moher Dávid Puskás Travis Marion Tina Lefrancois Jubin Payandeh Claude Cullinan Tracy Wilson Kurt Droll Michael Riediger Rabail Siddiqui Shalyn Littlefield Simrun Chahal Paige Wagar Prism S. Schneider Tosin Ogunleye Tanya Cherppukaran Karin Lienhard Nicholas Smith Sarah Anthony Krista Butt LaShann Selby Murali Kovvur Joshua Lawrence Skyler Sampson Kristin Turner Todd Jaeblon Haley K. Demyanovich Sneh Talwar Caroline Benzel Theresa A. Chockbengboun Devin S. Mullin Paul J. Appleton John J. Wixted Edward K. Rodriguez Michael F. McTague Katiri Wagner Kristina Brackpool Kate Hegermiller Nhi Nguyen Roman M. Natoli Courteney L. Fentz Maricela Diaz Jill Niceley Tammy Garrett Kyle J. Jeray Thomas M. Schaller Michael S. Sridhar John D. Adams Richard W. Gurich Stephanie L. Tanner Kyle Adams Michelle Donohue Emily Bray Calleigh Brignull Harper Sprouse Christina Tieszer

Extremity fractures are common, and most managed operatively; however, despite successful reduction, up to half of patients report persistent post-surgical pain. Furthermore, psychological factors such as stress, distress, anxiety, depression, catastrophizing, fear-avoidance behaviors have been associated with the development chronic The purpose this pilot study was examine feasibility a randomized controlled trial determine effect in-person cognitive behavioral therapy (CBT) vs. usual care...

10.1186/s40814-023-01430-y article EN cc-by Pilot and Feasibility Studies 2024-01-06
Kyle Gouveia Sheila Sprague Jodi Gallant Sarah MacRae Gina Del Fabbro and 90 more Sofia Bzovsky Paula McKay Herman Johal Jason W. Busse Mohit Bhandari Gerard P. Slobogean Lehana Thabane Randi E. McCabe Emil H. Schemitsch Gordon Guyatt PJ Devereaux Lehana Thabane Mohit Bhandari Ida Leah Gitajn Gerard P. Slobogean Emil H. Schemitsch Randi E. McCabe Matilda E. Nowakowski Eleni G. Hapidou Delia Chiaramonte Henrick Kehlet James S. Khan Matilda E. Nowakowski Aresh Sepehri Natalie Fleming Christy Shibu Diane Heels‐Ansdell Brad Petrisor Dale Williams Bill Ristevski Jamal Al-Asiri Matthew Denkers Kris Rajaratnam Kaitlyn Pusztai Sara Renaud Nicki Johal Steven Papp Karl‐André Lalonde Bradley Meulenkamp Allan Liew Manisha Mistry Braden Gammon Wade Gofton Geoffrey Wilkin Melanie Dodd-Moher Prism S. Schneider Tosin Ogunleye Tanya Cherppukaran Karin Lienhard Nicholas Smith Sarah Anthony Krista Butt Gerard P. Slobogean LaShann Selby Murali Kovvur Joshua Lawrence Skyler Sampson Kristin Turner Todd Jaeblon Haley K. Demyanovich Sneh Talwar Caroline Benzel Ida Leah Gitajn Theresa A. Chockbengboun Devin S. Mullin Paul J. Appleton John J. Wixted Edward K. Rodriguez Michael F. McTague Katiri Wagner Kristina Brackpool Kate Hegermiller Nhi Nguyen Roman M. Natoli Courteney L. Fentz Maricela Diaz Jill Niceley Tammy Garrett Jonathan Robin Kyle J. Jeray Thomas M. Schaller Michael S. Sridhar John D. Adams Richard W. Gurich Stephanie L. Tanner Kyle Adams Michelle Donohue Emily Bray Calleigh Brignull Harper Sprouse

Outcomes following surgery to operatively manage extremity fractures are variable, and up two-thirds of patients report chronic post-surgical pain. Preliminary evidence suggests that psychotherapy directed at improving coping skills reducing somatic vigilance may improve outcomes among fracture patients. The objective this pilot study was test the feasibility acceptability a randomized controlled trial comparing an online cognitive behavioural therapy (CBT) program versus usual care in with...

10.1186/s40814-024-01592-3 article EN cc-by-nc-nd Pilot and Feasibility Studies 2025-01-11
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