A5079046858- Orthopedic Infections and Treatments
- Bone fractures and treatments
- Hip and Femur Fractures
- Surgical site infection prevention
- Trauma and Emergency Care Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Orthopaedic implants and arthroplasty
- Pelvic and Acetabular Injuries
- Foot and Ankle Surgery
- Orthopedic Surgery and Rehabilitation
- Medical Imaging Techniques and Applications
- Musculoskeletal pain and rehabilitation
- Photoacoustic and Ultrasonic Imaging
- Diversity and Career in Medicine
- Traumatic Brain Injury and Neurovascular Disturbances
- Bacterial Identification and Susceptibility Testing
- Healthcare cost, quality, practices
- Diabetic Foot Ulcer Assessment and Management
- Hip disorders and treatments
- Ocular Infections and Treatments
- Optical Coherence Tomography Applications
- Bacterial biofilms and quorum sensing
- Optical Imaging and Spectroscopy Techniques
- MRI in cancer diagnosis
- Total Knee Arthroplasty Outcomes
Dartmouth–Hitchcock Medical Center
2017-2025
Dartmouth College
2020-2025
Dartmouth Psychiatric Research Center
2024
University of Maryland, Baltimore
2017-2024
Dartmouth Health
2023-2024
Population Health Research Institute
2024
Hamilton Health Sciences
2024
McMaster University
2024
Dartmouth Hospital
2022
Molloy College
2021
Studies evaluating surgical-site infection have had conflicting results with respect to the use of alcohol solutions containing iodine povacrylex or chlorhexidine gluconate as skin antisepsis before surgery repair a fractured limb (i.e., an extremity fracture).
Fracture-related infection is one of the most challenging complications in orthopaedic trauma surgery. However, effect on functional and pain-related outcomes has not been well established. The aims this study were to evaluate recovery for patients with fracture a deep surgical site compared without whether pain severity, social support, preinjury mental health have moderating magnitude direction relationship between recovery.
Objectives: The goals of this study are to evaluate mortality after Vancouver B periprosthetic fractures and determine predictors mortality; compare among patients with loose femoral stems treated revision arthroplasty versus fixation alone; radiographically “indeterminate” or fixation; the rate return surgery for who underwent compared fixation. Design: Retrospective study. Setting: Three academic level 1 trauma centers. Patients/Participants: Two hundred three fractures. Intervention: N/A....
Extremity fractures are common, and most managed operatively; however, despite successful reduction, up to half of patients report persistent post-surgical pain. Furthermore, psychological factors such as stress, distress, anxiety, depression, catastrophizing, fear-avoidance behaviors have been associated with the development chronic The purpose this pilot study was examine feasibility a randomized controlled trial determine effect in-person cognitive behavioral therapy (CBT) vs. usual care...
Outcomes following surgery to operatively manage extremity fractures are variable, and up two-thirds of patients report chronic post-surgical pain. Preliminary evidence suggests that psychotherapy directed at improving coping skills reducing somatic vigilance may improve outcomes among fracture patients. The objective this pilot study was test the feasibility acceptability a randomized controlled trial comparing an online cognitive behavioural therapy (CBT) program versus usual care in with...
SignificanceIn orthopedic trauma surgery, spatially structured biofilm ecosystems of bacteria that colonize devices account for up to 65% all healthcare infections, including tens millions people affected in the United States. These infections typically show increased resistance antibiotics due their structure and composition, which contributes significantly treatment failure. Anti-biofilm approaches are needed together with clinically usable microscopic-resolution imaging techniques...
Orthopedic implant-associated infections cause serious complications primarily attributed to bacterial biofilm formation and are often characterized by increased antibiotic resistance diminished treatment response. Yet, no methods currently exist identify biofilms intraoperatively-surgeons rely solely on their eyes hands cannot detect or differentiate infected tissue determine the location extent of contamination. As first step in addressing this unmet clinical need, here, we develop an...
(1) Compare the outcomes of patients with orthopaedic trauma culture-negative infection those pathogens identified; (2) identify incidence and describe common characteristics.Retrospective study.Two level 1 centers.A total 391 16 years age or older who underwent irrigation debridement for surgical site after having undergone fracture fixation were included.Patients cultures, antibiotic therapy was initiated.Treatment failure due to unsuccessful eradication time union.We found 9% infection....
In an intra-articular calcaneal fracture, the sustentaculum tali is generally thought to remain tightly bound talus by interosseous talocalcaneal ligaments, spring ligament, and deltoid providing a "constant" fragment that remains anatomically aligned. The extensile lateral approach commonly used for reduction based on this assumption, but because it provides only limited access medial aspect of calcaneus, indirect fracture required restore anatomic relationship these fragments sustentacular...
Introduction Patients who sustain orthopaedic trauma are at an increased risk of venous thromboembolism (VTE), including fatal pulmonary embolism (PE). Current guidelines recommend low-molecular-weight heparin (LMWH) for VTE prophylaxis in patients. However, emerging literature total joint arthroplasty patients suggests the potential clinical benefits with aspirin. The primary aim this trial is to compare aspirin LMWH as a thromboprophylaxis fracture Methods and analysis PREVENT CLOT...
Prompt administration of antibiotics is a critical component open fracture treatment. Traditional antibiotic recommendations have been first-generation cephalosporin for Gustilo Type-I and Type-II fractures, with the addition an aminoglycoside Type-III fractures penicillin soil contamination. However, concerns over changing bacterial patterns side effects aminoglycosides led to interest in other regimens. The purpose present study was describe adherence current prophylactic guidelines.We...
Background. The purpose of this study was to evaluate prognostic predictors complications and need for secondary surgery in a series calcaneal avulsion fractures. Methods. Thirty-three patients who sustained extra-articular fractures from 2002 2011 were retrospectively identified. Main outcome measurement surgical procedures. Secondary such as soft tissue loss fixation noted. Prognostic factors measures Results. There operations 12 cases. Of those, 10 (83%) had wound 5 (41.7%) failure...
The effects of varying the indocyanine green injection dose, rate, physiologic dispersion dye, and intravenous tubing volume propagate into shape magnitude arterial input function (AIF) during intraoperative fluorescence perfusion assessment, thereby altering observed kinetics images in vivo.Numerical simulations are used to demonstrate effect AIF on metrics derived from tissue concentration curves such as peak fluorescence, time-to-peak (TTP), egress slope.Forward models were produced by...
Background: The aim of this study was to determine the ability Harris heel view confirm placement sustentacular screw during calcaneal fixation. Methods: A 4.0 cancellous placed in a cadaveric specimen, from lateral medial 5 configurations: (1) within sustentaculum, (2) misdirected inferiorly (3) superiorly (4) anteriorly and (5) posteriorly sustentaculum. views were obtained at angulations analyzed placement. Results: anatomically radiographically confirmed by be sustentaculum all views. An...
Background. Bohler’s angle (BA) is the most commonly utilized radiographic measurement in study of calcaneus fractures and has been shown to be prognostic nature. Therefore, it critical that BA accurate as both therapeutic information relies on it. Oblique lateral radiographs can a cause error measurements. However, effects X-ray beam obliquity have not established literature. The purpose this was determine understand beam’s BA. Methods. A cadaver specimen imaged using C-arm obtain perfect...
The risk of developing a surgical site infection after extremity fracture repair is nearly 5 times greater than in most elective orthopedic procedures. For all procedures, it standard practice to prepare the operative with an antiseptic solution; however, there limited evidence guide choice solution used for repair.To compare effectiveness iodophor vs chlorhexidine solutions reduce infections and unplanned fracture-related reoperations patients who underwent repair.The PREP-IT (Program...
In this study, an indocyanine green (ICG)-based dynamic contrast- enhanced fluorescence imaging (DCE-FI) technique was evaluated as a method to provide objective real-time data on bone perfusion using porcine osteotomy model. DCE-FI with sequentially increasing injury osseous blood supply performed in 12 tibias. There were measurable, reproducible and predictable changes across each condition have been observed simple kinetic curve-derived variables well derived from novel bone-specific The...
Abstract Introduction: Traditional physical therapy (PT) requires patients to attend weekly in-office supervised appointments. However, between 50% and 70% of who would benefit do not receive prescribed PT due barriers access. Virtual Reality (VR) provides a platform for remote delivery address these access barriers. Methods: We developed VR-PT program consisting training, games, progress dashboard 3 common lower extremity exercises. enrolled orthopaedic trauma with injuries. Patients...