- Sperm and Testicular Function
- Sexual Differentiation and Disorders
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Spondyloarthritis Studies and Treatments
- Transcranial Magnetic Stimulation Studies
- Cell Adhesion Molecules Research
- Parental Involvement in Education
- Prostate Cancer Treatment and Research
- Neural and Behavioral Psychology Studies
- COVID-19 diagnosis using AI
- Vestibular and auditory disorders
- Urticaria and Related Conditions
- Epigenetics and DNA Methylation
- Vasculitis and related conditions
- Radiomics and Machine Learning in Medical Imaging
- Geophysical and Geoelectrical Methods
- Inflammatory Biomarkers in Disease Prognosis
- Effects and risks of endocrine disrupting chemicals
- Human Health and Disease
- IL-33, ST2, and ILC Pathways
- Folate and B Vitamins Research
- Acupuncture Treatment Research Studies
- Cardiovascular Conditions and Treatments
- Whipple's Disease and Interleukins
- Cystic Fibrosis Research Advances
Guangxi Medical University
2024-2025
Union Hospital
2025
Huazhong University of Science and Technology
2025
State Key Laboratory of Information Engineering in Surveying Mapping and Remote Sensing
2025
Taihe Hospital
2024
Science and Technology Department of Sichuan Province
2023-2024
Shanghai University of Medicine and Health Sciences
2023
Xinjiang Medical University
2023
Tumor Hospital of Xinjiang Medical University
2023
West China Medical Center of Sichuan University
2005-2022
Magnetotelluric (MT) forward modeling is fundamental for improving the accuracy and efficiency of MT inversion. Neural operators (NOs) have been effectively used rapid modeling, demonstrating their promising performance in solving modeling-related partial differential equations (PDEs). Particularly, they can obtain electromagnetic field at arbitrary locations frequencies. In these NOs, projection layers dominated by multi-layer perceptrons (MLPs), which may potentially reduce solution due to...
Lung adenocarcinoma (LUAD) is the leading cause of cancer-related deaths. High-resolution computed tomography (HRCT) has improved detection ground glass nodules (GGNs), which are early indicators lung cancer. Accurate assessment GGN invasiveness crucial for determining appropriate surgical approach. Dual-layer spectral detector (DLCT) offers advanced imaging capabilities, including electron density and iodine density, enhance evaluation invasiveness. This study aims to develop a machine...
Abstract Testis-specific protein Y-linked 1 (TSPY1) is expressed predominantly in adult human spermatogonia and functions the process of spermatogenesis; however, our understanding underlying mechanism limited. Here we observed that TSPY1, as an interacting partner TSPY-like 5 (TSPYL5), enhanced competitive binding TSPYL5 to ubiquitin-specific peptidase 7 (USP7) conjunction with p53. This activity, together its promotion expression by acting a transcription factor, resulted increased p53...
The testis‐specific protein, Y‐linked 1 ( TSPY 1), a newly recognized cancer/testis antigen, has been suggested to accelerate tumor progression. However, the mechanisms underlying cancer‐related function remain limited. By mining RNA sequencing data of lung and liver tumors from Cancer Genome Atlas, we found frequent ectopic expression in adenocarcinoma LUAD ) hepatocellular carcinoma LIHC ), male‐specific protein was associated with higher mortality rate worse overall survival patients ....
The present study aimed to investigate whether the cerebellar fastigial nucleus (FN) is involved in post‑stroke depression (PSD), and observe effect of direct cerebellar‑hypothalamic γ‑aminobutyric acid (GABA)ergic glutamatergic projections on PSD, order understand mechanisms underlying modulation mood emotion. Healthy Sprague‑Dawley rats were randomly divided into five groups: Sham‑operated, Stroke, FN lesion, decussation superior peduncle (XSCP) lesion groups. Sham surgery was performed...
Acute hypokalaemic paralysis is characterised by acute flaccid muscle weakness and has a complex aetiological spectrum. Herein we report, for the first time, case of unilateral adrenal hyperplasia accompanied periodic type I resulting from novel dominant mutation in CACNA1S. We present clinical features prognosis after adrenalectomy this case. A 43-year-old Han Chinese male presented with severe that remitted taking oral potassium. The patient had suffered attacks more than 20 years....
Abstract Testis‐specific protein Y‐encoded 1 ( TSPY1 ), a Y chromosome‐linked oncogene, is frequently activated in prostate cancers (PCa) and its expression correlated with the poor prognosis of PCa. However, cause ectopic transcription PCa remains unclear. Here, we observed that methylation status CpG islands (CGI) promoter was negatively level different human samples. The acetyl‐histone H4 trimethylated histone H3‐lysine 4, two post–translational modifications histones occupying promoter,...
The previous study showed that the Mandarin Tinnitus Questionnaire (MTQ) has satisfactory reliability and validity. We have also completed classification of severity tinnitus based on MTQ scores. In clinical studies, efficacy is often judged by whether results are statistically significant; however, statistical significance does not necessarily equate to significance, whereas minimum clinically important difference (MCID) scale does. following project, we will explore MCID MTQ.We recruited...
Objective Smartphone addiction is on the rise globally. This study aimed to compare rehabilitative effects of transcranial direct current stimulation (tDCS) and exergames smartphone among college students. Additionally, we discussed central mechanisms through changes in electroencephalography (EEG) provide clinical insights. Methods Thirty-six participants were randomly assigned three groups: control group, tDCS group (bilateral dorsolateral prefrontal cortex stimulation), exergame group....
Background Heredity and epigenetics affect the pathogenesis of microscopic polyangiitis (MPA). Tyrosine kinase 2 (TYK2) polymorphisms (rs2304256C > A, rs280519A G, rs12720270G A) may be potential protective factors against anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). Current research suggests that TYK2 is associated with various autoimmune diseases; however, no study has examined relationship between AAV. This assessed effect on susceptibility to MPA. Methods...