A5110644249- Plant Pathogens and Fungal Diseases
- Plant-Microbe Interactions and Immunity
- Plant pathogens and resistance mechanisms
- Plant Disease Management Techniques
- Plant Disease Resistance and Genetics
- Mycorrhizal Fungi and Plant Interactions
- Plant Pathogens and Resistance
- Nematode management and characterization studies
- Fungal Biology and Applications
- Entomopathogenic Microorganisms in Pest Control
- Soil Carbon and Nitrogen Dynamics
- Legume Nitrogen Fixing Symbiosis
- Plant tissue culture and regeneration
- Fungal Plant Pathogen Control
- Fungal and yeast genetics research
- Agronomic Practices and Intercropping Systems
- Plant and Fungal Interactions Research
- Mycotoxins in Agriculture and Food
- Garlic and Onion Studies
- Composting and Vermicomposting Techniques
- Plant Parasitism and Resistance
- Microbial Community Ecology and Physiology
- Yeasts and Rust Fungi Studies
- Biofuel production and bioconversion
- Agriculture, Plant Science, Crop Management
Genomics (United Kingdom)
2024
Sheffield Children's NHS Foundation Trust
2018-2023
Foundation for Arable Research
2019-2022
Sheffield Children's Hospital
2022
Lincoln University
2009-2019
University of Glasgow
2004-2018
Scion
2015-2017
Marrone Bio Innovations (United States)
2014-2016
Museum of New Zealand Te Papa Tongarewa
2015
Lincoln University - Pennsylvania
2002-2013
Low-molecular-weight organic compounds in root exudates play a key role plant-microorganism interactions by influencing the structure and function of soil microbial communities. Model exudate solutions, based on acids (OAs) (quinic, lactic, maleic acids) sugars (glucose, sucrose, fructose), previously identified rhizosphere Pinus radiata, were applied to microcosms. Root compound solutions stimulated dehydrogenase activity addition OAs increased pH. The active bacterial communities,...
Trichoderma species are soil-borne filamentous fungi widely utilized for their many plant health benefits, such as conferring improved growth, disease resistance and abiotic stress tolerance to hosts. Many able produce the auxin phytohormone indole-3-acetic acid (IAA), its production has been suggested promote root growth. Here we show that of IAA is strain dependent diverse external stimuli associated with production. In in vitro assays, Arabidopsis primary length was negatively affected by...
A conserved injury-defense mechanism is present in plants and animals, which the production of reactive oxygen species (ROS) lipid metabolism are essential to response. Here, we describe that filamentous fungus Trichoderma atroviride , injury results formation asexual reproduction structures restricted regenerating cells. High-throughput RNA-seq analyses response T. suggested an oxidative activation calcium-signaling pathways, as well participation metabolism, this phenomenon....
Following the diagnosis of a paediatric disorder caused by an apparently de novo mutation, recurrence risk 1-2% is frequently quoted due to possibility parental germline mosaicism; but for any specific couple, this figure usually incorrect. We present systematic approach providing individualized risk. By combining locus-specific sequencing multiple tissues detect occult mosaicism with long-read determine parent-of-origin we show that can stratify majority couples into one seven discrete...
Microbial denitrification plays a key role in determining the availability of soil nitrogen (N) to plants. However, factors influencing structure and function denitrifier communities rhizosphere remain unclear. Waterlogging can result root anoxia increased denitrification, leading significant N loss from potential nitrous oxide (N(2)O) emissions. This study investigated gene abundance, community activity wheat response limitation. Denitrifier differed that bulk soil, copy numbers (nirS,...
Introduction In October 2020, rapid prenatal exome sequencing (pES) was introduced into routine National Health Service (NHS) care in England, requiring the coordination of from specialist genetics, fetal medicine (FM) and laboratory services. This mixed methods study explored experiences professionals involved delivering pES service during first 2 years its delivery NHS. Methods A survey ( n = 159) semi-structured interviews 63) with healthcare professionals, including clinical geneticists,...
The rhizosphere competence of the biological control agent Trichoderma atroviride isolate C52 was studied on onion roots both in glasshouse and field when introduced into soil a range formulations. Proliferation T. formulation‐dependent. A pellet formulation maintained fungal concentration at 10 5 cfu per g soil, whereas solid‐substrate seed‐coating formulations gave concentrations 4 1 respectively. To facilitate rhizosphere‐competence studies, UP‐PCR band profile generated with primer L45...
Four fungi ( Chaetomium globosum, Trichoderma viride, T. harzianum, sp.) were capable of reducing the incidence onion white rot relative to untreated control in two soil‐box trials. When applied as a soil additive (sand: bran: fungal homogenate, 1:1:2) at rate 0‐1% wheat bran/g dry soil, all isolates provided levels disease equivalent fungicide (procymidone 0‐5 g a.i./100g seed) treatment. The best results achieved with globosum and (C62) which gave 78% 73% rot. respectively, trial 1 67%...
Auriculocondylar syndrome (ACS) is a rare craniofacial disorder consisting of micrognathia, mandibular condyle hypoplasia and specific malformation the ear at junction between lobe helix. Missense heterozygous mutations in phospholipase C, β 4 (PLCB4) guanine nucleotide binding protein (G protein), α inhibiting activity polypeptide 3 (GNAI3) genes have recently been identified ACS patients by exome sequencing. These are predicted to function within G protein-coupled endothelin receptor...
Soil-borne plant pathogens such as Rhizoctonia solani (Kuhn), Pythium ultimum (Trow) and Sclerotinia trifoliorum (Eriks) can reduce grass forage legume establishment. The potential for biocontrol of these by Trichoderma fungi was evaluated. Following dual culture assays, nine isolates (five atroviride one each hamatum, koningiopsis, viride virens) were chosen assessment in pot experiments. In the presence R. solani, perennial ryegrass (Lolium perenne L.) emergence increased 60–150% two T....
Isolates (a total of 129) R hizoctonia solani were collected from black scurf on potato tubers different potato‐growing regions in N ew Z ealand. Sequence analysis the nuclear ribosomal DNA internal transcribed spacer (r – ITS ) these isolates identified three anastomosis groups ( AG s), ‐3 PT , ‐2‐1 and ‐5. classified as widely distributed, whereas ‐5 confined to distinct locations. heterogeneity was 100 isolates. Variation sequence length r IGS 1 region also observed for selected ‐2‐1....