Yuanshui Sun

ORCID: 0000-0003-1237-9938
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About
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Research Areas
  • Gastric Cancer Management and Outcomes
  • Metastasis and carcinoma case studies
  • Enhanced Recovery After Surgery
  • Colorectal Cancer Surgical Treatments
  • Nutrition and Health in Aging
  • Gastrointestinal Tumor Research and Treatment
  • Gastrointestinal disorders and treatments
  • Esophageal and GI Pathology
  • Bariatric Surgery and Outcomes
  • GDF15 and Related Biomarkers
  • Clinical Nutrition and Gastroenterology
  • Helicobacter pylori-related gastroenterology studies
  • Colorectal Cancer Treatments and Studies
  • Appendicitis Diagnosis and Management
  • Cancer, Lipids, and Metabolism
  • Radiomics and Machine Learning in Medical Imaging
  • Pancreatic and Hepatic Oncology Research
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Cancer, Hypoxia, and Metabolism
  • Cancer Research and Treatments
  • Colorectal and Anal Carcinomas
  • Intestinal and Peritoneal Adhesions
  • Traditional Chinese Medicine Studies
  • Cancer survivorship and care
  • Hernia repair and management

Tongde Hospital of Zhejiang Province
2015-2024

Yahoo (United Kingdom)
2023

Shandong First Medical University
2020

Shandong Tumor Hospital
2020

Zhejiang Provincial People's Hospital
2006-2015

Zhejiang Hospital
2012

Early noninvasive screening of patients who would benefit from neoadjuvant chemotherapy (NCT) is essential for personalized treatment locally advanced gastric cancer (LAGC). The aim this study was to identify radio-clinical signatures pretreatment oversampled computed tomography (CT) images predict the response NCT and prognosis LAGC patients.LAGC were retrospectively recruited six hospitals January 2008 December 2021. An SE-ResNet50-based prediction system developed CT preprocessed with an...

10.1097/js9.0000000000000432 article EN cc-by-sa International Journal of Surgery 2023-05-03

To investigate the prognostic significance of tumor necrosis factor receptor (TNFR),-associated 6 (TRAF6),-and ubiquitin in gastric cancer patients. Biopsies rectus abdominis muscle were obtained intra operatively from 102 patients and 29 subjects undergoing surgery for benign abdominal diseases, TRAF6 mRNA expression proteasome proteolytic activities assessed. was significantly upregulated compared with control muscles. 67.65% (69/102) cancer. Over muscles associated TNM stage, level serum...

10.1186/1756-9966-31-81 article EN cc-by Journal of Experimental & Clinical Cancer Research 2012-09-26

Aim: PD-L1 monoclonal antibody-conjugated miR-130a/oxaliplatin-loaded immunoliposomes were constructed for enhanced therapeutic efficacy against gastric cancer. Materials & methods: The in vitro antitumor of the was evaluated by cell viability, invasion, apoptosis and western blot analysis vivo a HGC27-bearing tumor xenograft model. Results: inhibitory role miR-130a demonstrated HGC27 cells downregulation RAB5A FOCL1 signaling pathways. Consequently, PD-miOXNP exhibited strongest anticancer...

10.2217/nnm-2019-0073 article EN cc-by-nc-nd Nanomedicine 2019-07-01

We read with great interest the recent study evaluating effectiveness and costeffectiveness of blood-based biomarker screening for colorectal cancer (CRC) compared to established methods like fecal immunochemical testing (FIT) colonoscopy. 1The authors have contributed an important analysis in a rapidly evolving field.Nevertheless, we would provide some insights observations regarding certain methodological choices assumptions.First, notable area further exploration is influence genetic...

10.1093/jnci/djae340 article EN other-oa JNCI Journal of the National Cancer Institute 2024-12-19

BACKGROUND Myosin phosphatase target subunit 1 (MYPT1) serves as a subgroup of myosin phosphatases, and is frequently low-expressed in human cancers. However, little known about the effects MYPT1 gastric cancer (GC). MATERIAL AND METHODS In our study, expression was detected by quantitative real-time reverse transcription PCR (qRT-PCR) GC tissues, different advanced pathological stages preoperative postoperative patients. Kaplan-Meier analysis used to measure overall survival analyzed...

10.12659/msm.906852 article EN Medical Science Monitor 2018-04-24

Situs inversus totalis (SIT) is a rare congenital disease with series of clinical features characterized by mirror image distribution the viscera to normal anatomy.This study aims report 63-year-old male SIT patient gastric cancer preoperative diagnosis stage IIB (cT3N0M0), who underwent multi-disciplinary treatment (MDT) discussion and an abdominal enhancement CT for visceral evaluation ensure successful operation. A laparoscopic-assisted distal gastrectomy including D2 lymph node...

10.3389/fsurg.2023.1090910 article EN cc-by Frontiers in Surgery 2023-03-21

miR-205 is a tumor suppressor and plays an important role in invasiveness. However, the of human gastric cancer (GC) epithelial-mesenchymal transition (EMT) remains unclear. The aim this study was to investigate molecular mechanism regulation EMT GC invasion.Quantitative polymerase chain reaction (qPCR) used detect expression GC. Further, correlation between pathological parameters prognosis statistically analyzed. A transwell model evaluate effect miR-205-3p on invasion migration cells....

10.5230/jgc.2020.20.e19 article EN Journal of the Korean Gastric Cancer Association 2020-01-01

Malignant melanoma with gastric metastasis is extremely rare. We report a case of caused by malignant the lower limb.A 60-year-old woman was hospitalized for left plantar pain. The patient found black maculopapular eruption on sole her foot, which pain when pressed, and aggravated walking, so she went to our hospital treatment. On second day admission, lesion foot removed under local anesthesia, tissue sent pathological examination. Combined immunohistochemistry, it consistent melanoma....

10.3389/fonc.2023.1181728 article EN cc-by Frontiers in Oncology 2023-04-11

Introduction Small bowel obstruction is a common surgical emergency abdominal condition in clinical practice. Fecalith one of the rare causative factors, especially phytobezoars. Case Report We report case 66-year-old man admitted with “abdominal pain vomiting for 1 day.” Enhanced CT abdomen suggested incomplete small obstruction. The symptomatic treatment fasting, fluid replacement, gastrointestinal decompression, and antibiotics was conducted after patient to hospital. After 2 days...

10.3389/fsurg.2022.855904 article EN Frontiers in Surgery 2022-04-26

Introduction Left-sided appendicitis is a rare condition, and we report patient with left abdominal heterotopia of the right colon complicated by acute in lower quadrant. Case presentation A 39-year-old male was admitted to hospital following pain for 1 day. Imaging examination CT showed that appendix not clearly seen, mass found abdomen. Because patient's severe current diagnosis clear, after soliciting consent, performed laparoscopic exploration. This exploration revealed cecum ascending...

10.3389/fsurg.2022.896116 article EN cc-by Frontiers in Surgery 2022-08-24

Introduction: Abdominal cocoon is a very rare abdominal disease. mainly leads to intestinal obstruction, and with gastrointestinal perforation rare. Case Presentation: We report 63-year-old man who was admitted our hospital “persistent lower pain for one day”. CT examination revealed small amount of free gas in the cavity, ascites, perforation. An emergency operation performed. During operation, end right ileum found be conglutinated twisted into mass, local dilatation, wall black gangrene,...

10.3389/fsurg.2021.747151 article EN cc-by Frontiers in Surgery 2021-10-15

Objective To compare the surgical outcomes between laparoscopic and open wedge resection for gastrointestinal stromal tumors of stomach. Methods Clinical data 18 cases undergoing from June 2000 to August 2009 at Zhejiang Provincial People's Hospital were compared with 30 patients treated by surgery. The perioperative parameters prognosis two groups compared. Results Compared group,laparoscopic group was found longer operative time, less blood loss, requirement postoperative analgesia,...

10.3760/cma.j.issn.1671-0274.2011.08.011 article EN 2011-08-01

Adult intussusception is a rare disease that difficult to diagnose and treat even rarer when it caused by lipoma of the small intestine. We reported case intestine combined with intussusception, which can guide people in future clinical work. A 51-year-old female was admitted hospital "abdominal pain for 1 month." Enhanced computed tomography (CT) abdomen suggested left lower quadrant proximal intussusception. After excluding surgical contraindications, laparoscopic exploration performed on...

10.3389/fsurg.2022.915114 article EN cc-by Frontiers in Surgery 2022-06-30
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