- Advanced Electron Microscopy Techniques and Applications
- Electron and X-Ray Spectroscopy Techniques
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes Treatment and Management
- Methane Hydrates and Related Phenomena
- Graphene research and applications
- Cardiovascular Health and Disease Prevention
- Surface and Thin Film Phenomena
- Spacecraft and Cryogenic Technologies
- Nanopore and Nanochannel Transport Studies
- Advanced X-ray Imaging Techniques
- Metabolism, Diabetes, and Cancer
- Pancreatic function and diabetes
- Diabetic Foot Ulcer Assessment and Management
- Diabetes Management and Research
- Geological Studies and Exploration
- Liver Disease Diagnosis and Treatment
- Gout, Hyperuricemia, Uric Acid
- Electrohydrodynamics and Fluid Dynamics
- Force Microscopy Techniques and Applications
- Chronic Kidney Disease and Diabetes
- Solar-Powered Water Purification Methods
- Bone health and osteoporosis research
- Chronic Disease Management Strategies
- Cardiovascular Function and Risk Factors
Institute of Physics, Academia Sinica
2016-2025
National Taiwan University of Science and Technology
2024
Academia Sinica
2021-2023
Kaohsiung Municipal Hsiao-Kang Hospital
2015-2022
Kaohsiung Medical University
2014-2022
Kaohsiung Medical University Chung-Ho Memorial Hospital
2014-2022
Weatherford College
2022
National Tsing Hua University
2012-2018
Texas A&M University
2007
The triglyceride–glucose (TyG) index has been correlated with insulin resistance. We aim to investigate the role of TyG on cardiovascular (CV) events in type 2 diabetes mellitus and compare roles fasting glucose, hemoglobin A1c, predicting CV events. This retrospective study enrolled 3524 patients from Kaohsiung Medical University Research Database 2009 this longitudinal followed them until 2015. was calculated as log (fasting triglyceride level (mg/dL) × glucose (mg/dL)/2). included...
Obesity is an important risk factor for the development of diseases including diabetes, hypertension, and cardiovascular disease. However, few reports have investigated relationships between these obesity-related indices diabetic nephropathy. The aim this study was to evaluate associations markers with albuminuria advanced kidney disease in patients type 2 diabetes mellitus (DM). Obesity-related body mass index (BMI), waist-to-hip ratio (WHR), waist-to-height (WHtR), roundness (BRI),...
We demonstrate a new and simple process to fabricate tungsten tips with good control of the tip profile. In this process, we use commercial function generator without any electronic cutoff circuit or complex mechanical setup. The length can be varied from 160 μm 10 mm, corresponding an aspect ratio 1.6–100. radius curvature apex controlled size <10 nm. Surface roughness taper angle independently. Through etching parameters, length, curvature, surface roughness, suit different...
// Wei-Hao Hsu 1, 2 , Pi-Jung Hsiao 3 Pi-Chen Lin 1 Szu-Chia Chen 2, 3, 4, 5 Mei-Yueh Lee 4 and Shyi-Jang Shin 6 Division of Endocrinology Metabolism, Department Internal Medicine, Kaohsiung Medical University Hospital, University, Kaohsiung, Taiwan Municipal Hsiao-Kang Faculty College Graduate Institute Clinical Nephrology, Center for Lipid Glycomedicine Research, Correspondence to: Lee, email: lovellelee@hotmail.com Keywords: metformin; diabetes mellitus; chronic kidney disease; renal...
Patients with type 2 diabetes mellitus (DM) may experience chronic microvascular complications such as diabetic retinopathy (DR) and nephropathy (DN) during their lifetime. In clinical studies, serum uric acid concentration has been found to be associated DR DN. The goal of this study was evaluate the relationship between increases in level severity albuminuria Taiwanese patients DM. We recorded concentration, DR, by calculating urinary albumin-to-creatinine ratio (UACR) 385 multivariate...
Keywords: triglyceride-glucose index; microangiopathy; macroangiopathy; type 2 diabetes mellitus.
Halide perovskite quantum dots (PQDs) are promising materials for diverse applications including displays, light-emitting diodes, and solar cells due to their intriguing properties such as tunable bandgap, high photoluminescence yield, absorbance, narrow emission peaks. Despite the prosperous achievements over past several years, PQDs face severe challenges in terms of stability under different circumstances. Currently, researchers have overcome part problem, making sustainable water,...
Water hydrogen bonding is extremely versatile; ≈20 ice structures and several types of clathrate hydrate are identified. These crystalline water form at temperatures below room temperature and/or high pressure. Transmission electron microscopy used to study a new structure in state that prepared by sandwiching gas‐supersaturated between graphene layers under ambient conditions. In this state, molecules 3D hydrogen‐bonding network encloses gas‐filled cages 2–4 nm size. Herein, the derived...
Background: It is well known that diabetes mellitus impairs immunity and therefore an independent risk factor for tuberculosis. However, the influence of associated metabolic factors, such as hypertension, dyslipidemia gout has yet to be confirmed. This study aimed investigate whether strong association between tuberculosis from hypertension dyslipidemia, its treatment in elderly Taiwanese patients. Methods: A total 27,958 patients aged more than 65 years were identified National Health...
Introduction: Dipeptidyl peptidase 4 inhibitors (DPP-4 inhibitors) are incretin-based oral antidiabetic drugs. Previous studies have shown an association between increased plasma activity of DPP-4 and chronic hepatitis C virus (HCV) infection. may be associated with preventing the development HCV The aim this study was to investigate whether use is a decreased risk hepatocellular carcinoma (HCC) in patients diabetes mellitus (DM) Methods: In retrospective cohort study, we enrolled type 2...
Background: Diabetes mellitus is known to exacerbate bacterial infection, but its effect on the severity of viral infection has not been well studied. The thrombocytopenia an indicator dengue virus infection. We investigated whether diabetes associated with in dengue-infected patients. Methods: studied clinical characteristics 644 patients at a university hospital during epidemic 1 June 2002 31 December Taiwan. Platelet counts and biochemical data were compared between without diabetes....
The contact of water with graphene is fundamental importance and great interest for numerous promising applications, but how interacts remains unclear. Here we used atomic force microscopy (AFM) to investigate hydrophilic mica substrates some regions covered by mechanically exfoliated layers in water. In containing air gas close the saturation concentration (within ∼40%), cap-shaped nanostructures (or interfacial nanobubbles) ordered-stripe domains were observed on graphene-covered not pure...
Although some studies have reported that low ankle-brachial index (ABI) is associated with diabetic retinopathy (DR) in patients, it remains controversial as to which stage of DR. The aim this study assess whether peripheral artery disease (PAD), indicated by abnormally or high ABI, different stages DR patients type 2 diabetes mellitus (DM), and further evaluate the risk factors. A total 2001 (858 men 1143 women) DM who underwent ABI measurement an outpatient clinic were enrolled. PAD was...
Abstract Although some studies have reported an association between peripheral artery disease (PAD) and diabetic retinopathy (DR) in patients with diabetes, whether or not a causal relationship exists is unknown. The aim of this study was to investigate PAD, as indicated by abnormally low high ankle-brachial index (ABI), associated the development DR type 2 diabetes mellitus (DM) without DR. We enrolled 414 (221 men 193 women) DM who underwent ABI measurements at our outpatient clinic. PAD...
Emerging evidence suggests that glycemic variability may be a more reliable measure of control than mean HbA1c in type 2 diabetes mellitus. This study aimed to determine if is associated with cardiovascular events diabetic patients and different renal functions affect such association. longitudinal enrolled 8259 from the Kaohsiung Medical University Research Database 2009 were followed-up until 2015. Intra-individual HbA1C was defined as standard deviation (SD) hospitalization for coronary...
Abstract There are only a handful of scanning techniques that can provide surface topography at nanometre resolution. At the same time, there no methods capable non-invasive imaging three-dimensional thin free-standing crystalline material. Here we propose new technique—the divergent beam electron diffraction (DBED) and show it directly image inhomogeneity in atomic positions crystal. Such inhomogeneities transformed into intensity contrast first-order spots DBED patterns linearly depends on...
Background: Osteoporosis is highly prevalent in postmenopausal women and may result fractures disabilities. Total thyroidectomy has also been associated with loss of bone mass. The aim this cross-sectional study was to evaluate associations among nutritional status, skeletal muscle index markers turnover mineral density who had undergone total thyroidectomy. Methods: Fifty were included. Body composition measured using dual-energy X-ray absorptiometry (DXA). Geriatric Nutritional Risk Index...
Abstract Prediabetes increased risk of diabetes and diabetes‐related macrovascular microvascular complication. Glycohemoglobin (HbA 1c ) is clinically used as the gold standard for glycemic control diabetes. Glycated albumin (GA) an early Amadori‐type glycation protein between glucose serum albumin, which changes in a shorter period time than HbA superior to reflecting fluctuations blood glucose. In this study, we aim assess predictive value GA glycohemoglobin (HbA1c) on progression diabetic...
Transmission electron microscopy of gas-supersaturated water in graphene liquid cells shows two microscopic structures: polycrystalline nano-particles and a clathrate structure. The observations challenge conventional view gas water.