Systemic sclerosis (SSc) is a rare systemic autoimmune disease, characterized by progressive cutaneous and internal organ fibrosis. Orofacial manifestations of are extremely disabling treatment options limited. In this study, we aimed to assess the safety efficacy autologous fat grafting in face patients with sclerosis. We enrolled 16 SSc suffering from facial limited mouth opening capacity. Autologous injection ranging 15 40 ml was administered per patient, based on their morphology. The...

We report two cases of lichen planus following COVID-19 vaccination in middle-aged women, where the first patient presented with lichenplanopilaris (LPP) relapse and development 14 days after second dose AstraZeneca vaccine, other who had a previous scattered lesion LP which extended increased severity Sinopharm. The suggested cause could be due to immune dysregulation up regulation T cell lymphocytes was triggered vaccination. What supports our hypothesis that occurred vaccination, is one...

Acne vulgaris is a common skin disease that more in young population and it can be associated with some sequels after resolving the lesions. Post-inflammatory erythema one of these complications disturbing for patients does not have any definite treatment. This study was aimed to evaluate efficacy safety tranexamic acid (TA) as mesotherapy treatment post-acne (PAE) treatment.This clinical trial performed dermatology clinic on 17 persistent PAE (3 months acne recovery). Two sessions were by...

Abstract Background The management of melasma is still challenging, and new treatment modalities with favorable side effect profile are required. Methimazole, a peroxidase inhibitor, seems to have beneficial in the but there paucity studies for evaluation its efficacy. This double‐blinded trial was aimed evaluate efficacy safety methimazole vs hydroquinone 4% which gold standard melasma. Methods Fifty patients were enrolled randomly divided into two groups receive or 5% once daily 8 weeks....

Neutrophil or platelet to lymphocyte ratio (NLR and PLR) has been proposed be used as prognostic purposes in a variety of diseases. The aim this study was evaluate the usefulness these ratios monitoring response TNF-α-inhibitors psoriatic patients. Eighty patients were included treated with for 12 months based on drug protocol. Hematologic indices, including NLR PLR values assessed before after treatment. Data psoriasis area severity index (PASI), smoking behavior, alcohol intake habit, nail...

Summary Background and aim A comprehensive study comparing two different modalities, Nokor needle subcision ( NNS ) blunt cannula BCS ), for treatment of acne scars, has not been reported previously. The was to compare the effectiveness these methods based on patient's doctor's satisfaction measures, in addition late complications 3 months postsubcision. Method intervention Patients had 18‐65 years old, with scars both malar sides. They were treated at one side another side. monitored during...

In spite of the increasing prevalence polycystic ovary syndrome, there are restricted studies about different features PCOS. this study, we evaluate serum prolactin levels in PCOS patients and compare clinical hormone between with hyperprolactinemia normal prolactin.Serum level 330 were evaluated. If (equal to or less than 25 ng/ml) patient was considered normal. >25 ng/ml, then measured by Polyethylene glycol (PEG) precipitation method detect macroprolactinemia. Furthermore, brain MRI done...

Rituximab-induced serum sickness (RISS) is a rare complication of Rituximab (RTX) in immunobullous disorders. Clinicians should be aware the occurrence symptoms during RTX administration, and prompt initiation corticosteroid therapy crucial these patients. Additionally, RISS may occur with subsequent doses patients counseled accordingly.

Atopic dermatitis (AD) is a chronic skin disease that may be triggered by psychological conditions and several allergens. Patients with AD experienced exacerbation due to the COVID-19 pandemic lifestyle including home-quarantine increased stress. We obtained electronic data of 100 patients admitted our hospital from 2016 2019 called them specific phone line. Out patients, 43 were male, 57 female (mean age ± SD: 45.85 16.90). Sixty (37 females 23males; mean age: 42.22 14.71) confronted...

Steroid pulse therapy has shown satisfactory efficacy and safety in treating pemphigus vulgaris (PV). However, there is a paucity of data about the methylprednisolone, despite its frequent administration. The aim this study to evaluate steroid PV. In 10-year retrospective cohort study, 312 patients with PV, who had received methylprednisolone therapy, were included. Data sessions, adjuvant medications, dosages, remission rates, complications, mortalities collected from all patients. A total...

Isotretinoin has revolutionized the treatment of acne by improving cosmetic outcome and decreasing psychological damage. However, use isotretinoin is associated with significant side-effects such as mucocutaneous involvement, dyslipidaemia liver dysfunction, indicated increases in enzymes. The responsible enzyme for homocysteine metabolism, cystathionine-beta-synthase, might also be affected isotretinoin-induced which leads to hyperhomocysteinaemia, an independent risk factor thrombovascular...

Pyodermatitis-pyostomatitis vegetans is a rare inflammatory dermatosis. There strong association between pyodermatitis-pyostomatitis and bowel disease, particularly ulcerative colitis. Herein, we report case of with positive direct immunofluorescence staining findings review the literature for past 18 years to characterize its epidemiologic characteristics, associations, pathology indirect findings. The total number cases was 38, including 22 men 16 women, an average age forty. Direct had...

Background: Few studies have evaluated patients' motivations for seeking minimally invasive cosmetic procedures. Objective: This study aimed to assess the demographic characteristics and motivation of patients who seek procedures in two academic referral dermatology centers. Methods: The included adult facial at centers Tehran, Iran, between January 2019 June 2019. Results: majority were married, employed women with a mean age 39.6 ± 10.74 years. most common region face they expected change...

Multiple eccrine hidrocystomas (MEH) are benign cystic lesions of the sweat gland ducts. They characterized by translucent, skin-colored or bluish dome-shaped papules on face, causing cosmetic concern. Recently, botulinum toxin-A, because its antiperspirant properties, has been used to treat facial MEH. However, there only some case reports in literature.Here, we conducted a prospective study assess efficacy and safety intralesional injection toxin-A (Dysport) for treatment MEH.Twenty...