A5101803610- Oral microbiology and periodontitis research
- Nuclear Physics and Applications
- Dental Health and Care Utilization
- Streptococcal Infections and Treatments
- Nuclear physics research studies
- Catalysts for Methane Reforming
- Infective Endocarditis Diagnosis and Management
- Catalytic Processes in Materials Science
- Salivary Gland Disorders and Functions
- HIV/AIDS oral health manifestations
- Hydrogen Storage and Materials
- Bacterial biofilms and quorum sensing
- Catalysis and Hydrodesulfurization Studies
- Catalysis for Biomass Conversion
- Microbial Community Ecology and Physiology
- Polyoxometalates: Synthesis and Applications
- Advanced Battery Materials and Technologies
- Endodontics and Root Canal Treatments
- Methane Hydrates and Related Phenomena
- Particle accelerators and beam dynamics
- Metal-Organic Frameworks: Synthesis and Applications
- Oral Health Pathology and Treatment
- Thermochemical Biomass Conversion Processes
- Dental Radiography and Imaging
- Carbon dioxide utilization in catalysis
Hirosaki University
2017-2024
Matsumoto Dental University
2015-2024
Japan Research Institute
2018
Kanagawa University
2009-2017
Kyushu Dental University
2005-2015
RIKEN Nishina Center
2008-2013
The University of Tokyo
1992-2009
RIKEN
1992-2009
Kyushu University
1997-2008
Tokyo University of Marine Science and Technology
2008
Although poor oral health influences the occurrence of pulmonary infection in elderly people, it is unclear how degree linked to mortality from infection. Therefore, we evaluated relationship between and four-year pneumonia an Japanese population. The study population consisted 697 (277 males, 420 females) 1282 individuals who were 80 years old 1997. Data on systemic obtained by means questionnaires, physical examinations, laboratory blood tests. One hundred eight persons died 1998 2002. Of...
ABSTRACT Streptococcus mutans is implicated as a major etiological agent in human dental caries, and one of the important virulence properties this organism its ability to form biofilms (dental plaque) on tooth surfaces. We examined role autoinducer-2 (AI-2) S. biofilm formation by constructing GS-5 luxS -null mutant. Biofilm mutant 0.5% sucrose defined medium was found be markedly attenuated compared wild type. Scanning electron microscopy also revealed that formed larger clumps parental...
ABSTRACT Streptococcus mutans has been strongly implicated as the principal etiological agent in dental caries. One of important virulence properties these organisms is their ability to form biofilms known plaque on tooth surfaces. Since roles sucrose and glucosyltransferases S. biofilm formation have well documented, we focused our attention sucrose-independent factors. We initially identified several mutants that appear be defective abiotic surfaces by an insertional inactivation...
Tin-based electrocatalysts with different tin species distributions were deposited on the carbon paper substrate by three electrodeposition methods and applied to selective electroreduction of dioxide formic acid. Among them, prepared using unipolar pulse (UPED) method exhibited maximum HCOOH faradaic efficiency 89% at −1.7 V (vs Ag/AgCl) a current density 6.0 mA cm–2 long-term stability in 0.1 M CO2-saturated KHCO3 solution. Moreover, effects surface oxides performance tin-based...
Design and fabrication of efficient electrocatalysts is essential for electrochemical reduction carbon dioxide (CO2). In this work, bismuth (Bi)-doped SnO nanosheets were grown on copper foam (Bi-SnO/Cu foam) by a one-step hydrothermal reaction method applied the CO2 to formic acid (HCOOH). The experimental results indicated that Bi doping stabilized divalent tin (Sn2+) existing surface electrocatalyst, making it difficult be reduced metallic (Sn0) during process. addition, combining with...
The development of highly efficient eletrocatalysts for water electrolysis application is a rising hot issue; especially the oxygen evolution reaction (OER) attracted wide attention due to significant overpential derived by complex four electron-transfer coupled reaction. In this study, hierarchical NiO microflake@NiFe-layer double hydroxide (LDH) nanosheet core–shell arrays on nickel foam were fabricated combining two-step hydrothermal synthesis and calcination process. Due...
ABSTRACT A 5′ nuclease TaqMan PCR assay was developed for the quantitative detection of major cariogenic bacteria Streptococcus mutans and sobrinus . The absolute relative numbers were measured by this method. This will be useful quantifying these organisms in oral specimens analyzing biofilm formation.
Background: Porphyromonas gingivalis , Treponema denticola and Tannerella forsythia (previously T. forsythensis ), which are regarded as the principal periodontopathogenic bacteria, exist a consortium in subgingival biofilms. We aimed to examine quantitative relationships between P . T biofilms relationship quantity prevalence of these three bacteria site‐specific periodontal health. Methods: This study was cross‐sectional. The population consisted 35 adult subjects who visited Kyushu Dental...
A 5' nuclease TaqMan PCR was developed for the quantitative detection of periodontopathic bacteria Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis. The relative numbers were measured by comparative threshold cycle method. This simplified method is a way obtaining quantities these organisms from specimens monitoring effect therapy.
Findings from several studies suggest associations between tooth loss and health outcomes, including malnutrition, poor quality of life, mortality, in older individuals. However, limited information is available regarding whether those remain true very elderly subjects after adequately considering confounding factors such as sex smoking status. Herein, we determined the number teeth 80-year-old an independent predictor mortality. We initially contacted 1282 community-dwelling individuals...
The glucosyltransferases of Streptococcus mutans are recognized as important virulence factors for this cariogenic bacterium. To study the expression gtfB gene S. in biofilms, a promoter (PgtfB)–green fluorescent protein (GFP) reporter system was developed. A Streptococcus–Escherichia coli shuttle vector harbouring PgtfB::gfp cassette introduced into GS-5, and GFP by transformed cells confirmed fluorescence microscopy. Furthermore, confocal laser scanning microscopy carried out on biofilms...
Many studies have examined the presence of Porphyromonas gingivalis in periodontal pockets. However, monitoring number bacterial cells is difficult. In this study, we performed quantitative analyses P. to clarify relationship between numbers organism and status. Using TaqMan real‐time PCR system, found a significant positive correlation ( P < 0.0001) pocket depth. The slope regression line indicated that for every 1‐mm increase depth, increased 10‐ fold. There was also reduction 0.01)...
ABSTRACT Loop-mediated isothermal amplification (LAMP), a novel nucleic acid method, was developed for the rapid detection of major periodontal pathogens Porphyromonas gingivalis , Tannerella forsythia and Treponema denticola . The LAMP method amplifies DNA with high specificity, efficiency, rapidity under conditions using set four specially designed primers polymerase strand displacement activity. In this study, we initially assays to detect these bacteria evaluated specificity sensitivity...