A5035027309- Polymer crystallization and properties
- biodegradable polymer synthesis and properties
- Polymer Nanocomposites and Properties
- Bladder and Urothelial Cancer Treatments
- Urinary and Genital Oncology Studies
- Fuel Cells and Related Materials
- Membrane-based Ion Separation Techniques
- Fiber-reinforced polymer composites
- Epigenetics and DNA Methylation
- Membrane Separation Technologies
- Ferroptosis and cancer prognosis
- Urological Disorders and Treatments
- Cancer Immunotherapy and Biomarkers
- Ubiquitin and proteasome pathways
- Carbon dioxide utilization in catalysis
- Cancer, Lipids, and Metabolism
- Nanoplatforms for cancer theranostics
- Natural Fiber Reinforced Composites
- Advanced battery technologies research
- Inflammasome and immune disorders
- Electrocatalysts for Energy Conversion
- Immunotherapy and Immune Responses
- Synthesis and properties of polymers
- Estrogen and related hormone effects
- Silicone and Siloxane Chemistry
Third Affiliated Hospital of Sun Yat-sen University
2023-2025
Sun Yat-sen University
2023-2025
Shenyang Aerospace University
2016-2023
Central Hospital Affiliated to Shenyang Medical College
2023
Second Xiangya Hospital of Central South University
2020-2022
Central South University
2020-2022
Jilin University
2012-2013
Background: Bladder cancer is the fourth and tenth most common malignancy in men women worldwide, respectively.One of main reasons for unsatisfactory therapeutic control bladder that molecular biological mechanism complex.Gasdermin B (GSDMB) one member gasdermin family participates regulation cell pyroptosis.The role GSDMB has not been studied to date.Methods: TCGA database was used exam clinical relevance GSDMB.Functional assays such as MTT assay, Celigo fluorescent cell-counting Annexin...
Clear cell renal carcinoma (ccRCC) is the most common subtype of and has highest mortality rate.For metastatic RCC, systemic drug therapy important method in addition to surgical tumor reduction.In recent years, tyrosine kinase inhibitors (TKIs) targeting angiogenesis have been applied treat ccRCC achieved profound therapeutic effects.It reported that patients receiving antiangiogenic will develop resistance within 15 months.The mechanism targeted extremely complex not clarified.Ovarian...
CD155 is a crucial factor in the regulation of T cell function and contributes to immune escape. upregulation has been found several types cancer. However, mechanism by which regulates CD8+ colorectal cancer remains unclear. Here we investigated role function. We studied expression tissues through western blot, immunohistochemistry, TCGA database. verified effects on functions cells vitro experiments. demonstrated that affects migration thus promotes tumor growth mouse subcutaneous model....
Clear cell renal carcinoma (ccRCC) accounts for 85% of all malignant tumors.Currently, the pathogenesis ccRCC is not fully understood.Chromobox (CBX) family proteins are major subunits PcG complexes and implicated in regulating mammalian development.The CBX consists eight members, namely, CBX1-8.Numerous studies have highlighted that each protein exhibits distinct functions prognostic roles specific cancer types.In this study, silico analysis indicated CBX7 was downregulated correlated with...
Styrene (St) was used as comonomer and glycidyl methacrylate (GMA) grafting monomer to prepare SEBS-g-(GMA-co-St) graft copolymers via melt grafting. Then, the were employed a compatibilizer for blending polypropylene (PP) hydrogenated styrene-butadiene-styrene (SEBS) triblock copolymers. The effects of amount GMA in on thermal properties, rheology, crystallization, optical mechanical microstructure blends investigated. results show that St successfully grafted onto SEBS. copolymer...
Glycidyl methacrylate (GMA) and styrene (St) were used as the graft monomer co-graft monomer, respectively, grafted onto poly(ethylene-octene) (POE) linear low-density polyethylene (LLDPE) to prepare a series of GMA-functionalized (POE/LLDPE)-g-(GMA-co-St) copolymers. The copolymers then blended with poly(butylene terephthalate) (PBT) produce PBT/(POE/LLDPE)-g-(GMA-co-St) blends. effects grafting factors copolymer content on mechanical properties, thermal rheology, morphology, deformation...
A core–shell polybutadiene-graft-polystyrene (PB-g-PS) copolymer with a ratio of 70/30 (wt/wt) was synthesized by redox-initiated emulsion graft polymerization. Compatible polymers polyphenylene ether (PPE) and polystyrene (PS) blend were toughened the addition high-impact (HIPS) PB-g-PS copolymer, content PB rubber in whole matrix kept at 17.4 wt %. The influence composition synergistic toughening effect different-sized particles on mechanical properties, morphology, deformation mechanism...
Immunotherapy for colorectal cancer (CRC) with microsatellite stability (MSS) and mismatch repair proficiency (pMMR) has shown limited success in clinical trials. The combination of immunomodulators immune checkpoint inhibitors (ICIs) is a potential strategy treating CRC. Histone deacetylase (HDAC) indoleamine 2,3-dioxygenase 1 (IDO1) expression CRC tissues adjacent normal was analyzed via database analysis, immunohistochemistry, western blotting. A nanodrug designated as NP-I/P subsequently...
Objective Radical nephroureterectomy remains the gold standard for surgical treatment of upper urinary tract urothelial carcinoma (UTUC). Based on previous research, we prospectively compared advantages transperitoneal laparoscopic radical (TLNU) with a three-port technique in single position versus retroperitoneal (RLNU). Methods We evaluated 48 patients diagnosed UTUC at our institution from January 2015 to October 2019. The underwent either TLNU (n = 24) or RLNU 24). randomly assigned...
Abstract This paper presents the synthesis of core‐shell polybutadiene‐graft‐polystyrene (PB‐g‐PS) with a ratio 70/30 in copolymer. The polyphenylene oxide (PPO)/polystyrene (PS) alloy is toughened by high‐impact polystyrene (HIPS) and PB‐g‐PS effect entanglement density on mechanical properties deformation mechanism blends investigated. found to increase increasing PPO content. indicated that HIPS have excellent synergic toughening effects PPO/PS alloy, impact strength elongation at break...
Abstract Background Bladder cancer is the fourth and tenth most common malignancy in men women worldwide, respectively. One of main reasons for unsatisfactory therapeutic control bladder that molecular biological mechanism complex. Gasdermin B (GSDMB) one member gasdermin family participates regulation cell pyroptosis. The role GSDMB has not been studied to date. Methods clinical relevance was examined by TCGA data set. Functional assays, such as MTT assay, Celigo fluorescent cell-counting...
This work focused on the synthesis of a series poly(arylene ether ketone) random copolymers with various controlled pendant carboxylic acid groups (PEAK-COOH) by direct copolymerization method and preparation antifouling ultrafiltration membranes via conventional immersion precipitation phase inversion method. The morphologies PEAK-COOH were investigated scanning electron microscopy. In addition, surface hydrophilicity charged property studied water contact angle membrane potential...
Background A 52-year-old middle-aged woman developed fatigue, poor appetite and elevated CRE levels 6 months ago without known causes of these symptoms. After repeated anti-infective renal function improvement treatment, her symptoms did not significantly improve local progress. Pathological examination confirmed soft spot disease left kidney bladder. Tests Plain computed tomography (CT) scan the lungs urinary system; CT enhancement abdomen pelvis, magnetic resonance (MR) pelvis; positron...