William R. Bobier

ORCID: 0000-0003-1302-985X
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About
Contact & Profiles
Research Areas
  • Ophthalmology and Visual Impairment Studies
  • Visual perception and processing mechanisms
  • Glaucoma and retinal disorders
  • Corneal surgery and disorders
  • Advanced Optical Imaging Technologies
  • Vestibular and auditory disorders
  • Retinal Diseases and Treatments
  • Retinopathy of Prematurity Studies
  • Tactile and Sensory Interactions
  • Advanced Optical Sensing Technologies
  • Intraocular Surgery and Lenses
  • Ocular and Laser Science Research
  • Ophthalmology and Eye Disorders
  • Optical Imaging and Spectroscopy Techniques
  • Retinal Imaging and Analysis
  • Photorefractive and Nonlinear Optics
  • Advanced Neuroimaging Techniques and Applications
  • Motor Control and Adaptation
  • Reading and Literacy Development
  • Leaf Properties and Growth Measurement
  • Ocular Surface and Contact Lens
  • Avian ecology and behavior
  • Ocular Oncology and Treatments
  • Action Observation and Synchronization
  • Digital Imaging in Medicine

University of Waterloo
2014-2023

McGill University
2011

University of Auckland
2011

Fundação Armando Alvares Penteado
2009-2010

Association for Research in Vision and Ophthalmology
2007

University of Guelph
2007

Welch Allyn (United States)
2007

Canada Foundation for Innovation
2004

Natural Sciences and Engineering Research Council
2004

College of Optometrists
1978-1985

<h3>Importance</h3> Binocular amblyopia treatment using contrast-rebalanced stimuli showed promise in laboratory studies and requires clinical trial investigation a home-based setting. <h3>Objective</h3> To compare the effectiveness of binocular video game with placebo for improving visual functions older children adults. <h3>Design, Setting, Participants</h3> The Treatment Amblyopia Using Videogames was multicenter, double-masked, randomized trial. Between March 2014 June 2016, 115...

10.1001/jamaophthalmol.2017.6090 article EN JAMA Ophthalmology 2018-01-04

BackgroundOcclusion therapy for amblyopia is predicated on the idea that primarily a disorder of monocular vision; however, there growing evidence patients with have structurally intact binocular visual system rendered functionally due to suppression. Furthermore, we found dichoptic treatment intervention designed directly target suppression can result in clinically significant improvement both and function adult amblyopia. The fact occurs absence any fellow eye occlusion suggests is, part,...

10.1111/cxo.12192 article EN Clinical and Experimental Optometry 2014-08-18

An optical analysis of a photographic technique, "eccentric photorefraction," designed to measure refraction and accommodative states along single meridian the eye, is presented. Empirical measures taken from model eye support theoretical derivation. The application technique for use with human infants discussed reference measurements eyes.

10.1097/00006324-198509000-00006 article EN Optometry and Vision Science 1985-09-01

To compare emergent literacy skills in uncorrected hyperopic and emmetropic children. "Hyperopes" (>or=2.00 D sphere along the most meridian; n=13; aged 67+/-13 mo) "emmetropes" (<or=1.50 n=19; 58+/-12 were tested for visual acuity (VA) assessed their [three standard tests (letter/word reading skills, receptive vocabulary phonological awareness) an experimental test of orthography]. Parents completed a survey family demographics, health/developmental concerns home experiences. Visual motor...

10.1097/opx.0b013e318157a67a article EN Optometry and Vision Science 2007-11-01

Abstract Purpose Optical treatment alone can improve visual acuity ( VA ) in children with amblyopia, thus clinical trials investigating additional amblyopia therapies (such as patching or videogames) for require a preceding optical phase. Emerging adult patients are entering trials. It is unknown whether effective adults and an correction phase required involving adults. Methods We examined participants who underwent the Binocular Treatment Amblyopia using Videogames BRAVO trial ANZCTR ID :...

10.1111/opo.12437 article EN Ophthalmic and Physiological Optics 2018-01-22

OBJECTIVES: The validity (sensitivity and specificity) of a preschool vision screening program was measured over 3-year period to determine how well strabismus significant refractive errors could be detected. METHODS: Public health nurses were trained administer tests visual acuity, stereoacuity, ocular alignment. Failure on any test, acuity 6/9 or less, stereoacuity less than 100 seconds arc, an apparent misalignment the eyes resulted in referral eye care practitioner. An age-matched...

10.2105/ajph.89.2.193 article EN American Journal of Public Health 1999-02-01

To better understand the neural basis of sensory dominance in normal population, we applied a recently established test designed to quantify degree suppression amblyopia participants with binocular vision.This quantifies dichoptic imbalance coherent motion sensitivity by manipulating contrast stimuli seen two eyes. The at which balanced occurs is referred as "balance point" and an estimate suppression. We apply same logic measurement measuring distribution points" within population.We show...

10.1097/opx.0b013e3182217295 article EN Optometry and Vision Science 2011-06-03

Purpose.: Evidence is accumulating that suppression may be the cause of amblyopia rather than a secondary consequence mismatched retinal images. For example, treatment interventions target lead to better binocular and monocular outcomes. Furthermore, it has recently been demonstrated measurement have prognostic value for patching therapy. these reasons, in clinic needs improved beyond methods are currently available, which provide binary outcome. Methods.: We describe novel quantitative...

10.1167/iovs.12-11314 article EN Investigative Ophthalmology & Visual Science 2013-09-13

Amblyopia is a common neurodevelopmental disorder of vision that characterised by visual impairment in one eye and compromised binocular function. Existing evidence-based treatments for children include patching the nonamblyopic to encourage use amblyopic eye. Currently there are no widely accepted available adults with amblyopia. The aim this trial assess efficacy new binocular, videogame-based treatment amblyopia older adults. We hypothesise will significantly improve acuity relative...

10.1186/s13063-016-1635-3 article EN cc-by Trials 2016-10-18

Abstract Purpose To test the hypothesis that fixational stability of amblyopic eye in strabismics will improve when viewing provides both bifoveal fixation and reduced inter‐ocular suppression by reducing contrast to fellow eye. Methods Seven strabismic amblyopes (Age: 29.2 ± 9 years; five esotropes two exotropes) showing clinical characteristics central were recruited. Interocular was measured a global motion task. For each participant, balance point determined which defined levels for...

10.1111/opo.12119 article EN Ophthalmic and Physiological Optics 2014-02-05

A geometrical-optical technique is used to predict the changes in slope of eccentric-photorefraction intensity profiles as a function refractive state. We investigate how vary with state for different light source configurations and monochromatic aberrations eye. The best possible configuration extends from zero eccentricity (to increase sensitivity reduce dead zone) high working range). An advantage using extended that profile reflex more linear sources than point sources. It also shown...

10.1364/josaa.14.002547 article EN Journal of the Optical Society of America A 1997-10-01

Purpose. To examine the contribution of corneal and lenticular components to total astigmatism in preschool low high astigmats determine whether there was any compensation for by component. Methods. Cycloplegic refractive keratometric measures using Retinomax K-Plus (Nikon Inc., Melville, NY) were conducted on 129 children (mean age, 51.1 ± 8.4 mo) Oxford County, Canada. We divided sample into (total cylinder ≥1 D; mean, 1.38 0.43 n = 29) normal ≤ 0.75 0.22 0.20 100). Measures transposed J0...

10.1097/00006324-200407000-00015 article EN Optometry and Vision Science 2004-07-01

Citation information: Sreenivasan V, Irving EL &amp; Bobier WR. Effect of near adds on the variability accommodative response in myopic children. Ophthalmic Physiol Opt 2011, 31 , 145–154. doi: 10.1111/j.1475‐1313.2010.00818.x Abstract Purpose: Higher (VAR) has been reported myopes and speculated to be a possible risk factor for progression myopia. We investigated whether +2D −2D were capable altering also determined influence phoria viewing condition (binocular vs monocular) VAR emmetropic...

10.1111/j.1475-1313.2010.00818.x article EN Ophthalmic and Physiological Optics 2011-02-10

Five subjects showing slow accommodative responses were given orthoptic treatment. Speed of response improved after 3 to 6 weeks. No regressions evident 18 weeks the cessation training. Slow found in with normal phorias and fusion limits. The technique dynamic photorefraction is introduced for clinical measurement time characteristics.

10.1097/00006324-198308000-00006 article EN Optometry and Vision Science 1983-08-01

A critical challenge in biomedical imaging is to optimally balance the trade-off among image resolution, signal-to-noise ratio, and acquisition time.Acquiring a high-resolution possible; however, it either expensive or time consuming both.Resolution also limited by physical properties of device, such as nature size input source radiation optics device.Super-resolution (SR), which an off-line approach for improving resolution image, free these trade-offs.Several methodologies, interpolation,...

10.1117/1.jbo.19.5.056002 article EN Journal of Biomedical Optics 2014-05-01
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