A5078128904- Catalytic C–H Functionalization Methods
- Cyclopropane Reaction Mechanisms
- Fiber-reinforced polymer composites
- Catalytic Cross-Coupling Reactions
- Catalytic Alkyne Reactions
- Asymmetric Hydrogenation and Catalysis
- Polymer composites and self-healing
- biodegradable polymer synthesis and properties
- Asymmetric Synthesis and Catalysis
- Synthesis and Catalytic Reactions
- Surface Modification and Superhydrophobicity
- Synthetic Organic Chemistry Methods
- Synthesis and properties of polymers
- Click Chemistry and Applications
- Chemical Synthesis and Reactions
- Chemical Synthesis and Analysis
- Angiogenesis and VEGF in Cancer
- Polymer crystallization and properties
- Fluorine in Organic Chemistry
- Polymer Nanocomposites and Properties
- Oxidative Organic Chemistry Reactions
- Heparin-Induced Thrombocytopenia and Thrombosis
- Graphene research and applications
- Traditional and Medicinal Uses of Annonaceae
- Simulation and Modeling Applications
Changchun University of Technology
2018-2025
Tianjin Medical University Cancer Institute and Hospital
2025
Southwest Hospital
2025
Army Medical University
2025
Changchun University
2005-2025
Beijing Technology and Business University
2023
Institute of Hematology & Blood Diseases Hospital
2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2023
Shanghai Medical College of Fudan University
2023
Nanjing University of Aeronautics and Astronautics
2023
A highly enantioselective palladium-catalyzed iodine atom transfer cycloisomerization of unactivated alkenes has been developed. This represents the first example carboiodination olefin-tethered aryl iodides, which provides a perfect economy method to construct series optically active 2,3-dihydrobenzofuran, indolines and chromane bearing an alkyl iodide group in moderate good yields. Moreover, use readily available starting materials, broad substrate scope, high selectivity, mild reaction...
Reinforcement mechanism introduced by the fully bio-based HWPU sizing agent.
The first example of highly enantioselective intramolecular hydroarylation allyl aryl ethers was realized by palladium-catalyzed reductive heck reactions utilizing a new chiral sulfinamide phosphine ligand (N-Me-XuPhos). N-Me-XuPhos can be easily prepared on gram scale from readily available starting materials in one-pot synthesis approach. A series optically active 2,3-dihydrobenzofurans bearing quaternary stereocenter were obtained good yields and with excellent enantioselectivities....
Abstract Sonogashira‐type cross‐couplings are one of the most significant alkynylations in organic chemistry. One first palladium‐catalyzed intramolecular Heck/Sonogashira reactions alkenes with terminal alkynes is now reported. With this method, a variety uniquely substituted chiral benzene‐fused heterocycles bearing propargyl‐substituted all‐carbon quaternary stereocenter were obtained straightforward, high‐yielding, and highly stereoselective manner under mild conditions. Salient features...
Abstract The first example of highly enantioselective fluoroarylation gem‐difluoroalkenes with aryl halides is presented by using a new chiral sulfinamide phosphine ( Sadphos ) type ligand TY‐Phos . N‐Me‐ can be easily synthesized on gram scale from readily available starting materials in three steps. Salient features this work including materials, good yields, high enantioselectivities as well broad substrate scope make approach very practical and attractive. Notably, the asymmetric...
Abstract To address the issue of inadequate interfacial adhesion in carbon fiber/poly ether ketone (CF/PEEK) composites, an innovative approach that combines carbene chemistry and sizing treatment was meticulously designed to achieve remarkable synergistic enhancement. Specifically, cyano groups were chemical‐grafted on CF surface via reaction. Meanwhile, a water‐based self‐catalyzed cross‐linkable PENK‐NH 2 agent with good storage stability prepared. Noteworthy, presence amino as blocking...
The synthetic potential of highly directional formal insertion a carbene between carbon and hydrogen carbon–hydrogen bond has recently been developed for intramolecular reactions that lead to compounds biological medicinal interest. Stereoselective regiocontrolled processes from diazoacetate reactants, catalyzed by dirhodium(II) with chiral carboxamidate ligands, provide efficient selective access as diverse enterolactone, baclofen, imperanene, xylolactone, rolipram. A comparison the C–H...
A base-assisted metal species modulation mechanism enables Ni-catalyzed stereodivergent transfer semihydrogenation of alkynes with water, delivering both olefinic isomers smoothly using cheap and nontoxic catalysts additives. Different from most precedents, in which E-alkenes derive the isomerization Z-alkene products, were formed orthogonal catalytic pathways. Mechanistic studies suggest base as a key early element reaction pathways: by adding different bases, nickel disparate valence...
Abstract The inherent structural properties and elevated processing temperatures of thermoplastic resins present new challenges in the realm carbon fiber (CF) sizing agents. Consequently, a water‐based cross‐linkable nitro‐phthalonitrile capped polyfluorenyl ether ketone agent was meticulously designed. exhibits superior storage stability, encapsulating particles spanning dimensions from 66.51 to 87.71 nm. mechanism during hot‐pressing stage involves self‐crosslinking nitrile groups toward...
Abstract A highly enantioselective dicarbofunctionalization of unactivated alkenes was implemented by a Pd‐catalyzed asymmetric tandem Heck/Suzuki coupling reaction. This reaction represents the first example intramolecular cyclization/cross‐coupling olefin‐tethered aryl halides with alkyl‐, alkenyl‐ or arylboronic acids, and provides rapid access to number chiral compounds, such as dihydrobenzofurans, indolines, chromanes, indanes bearing quaternary stereocenter, in good yields excellent...
A palladium catalyzed enantioselective Heck/borylation reaction of alkene-tethered aryl iodides was realized, delivering a variety 2,3-dihydrobenzofuranyl boronic esters in high yield with excellent enantioselectivity.
The carbon fiber/hydroxyapatite (CF/HA) reinforcement with a three-dimensional flower-like structure was rapidly fabricated the biomimetic mineralization method to strengthen interfacial performance and bioactivity of fiber/polyether ether ketone (CF/PEEK) composites. Silk fibroin (SF), which can construct robust interphase between CF PEEK, supported an organic template regulate growth inorganic HA. properties were markedly enhanced through mechanical interlocking interface adhesion induced...