A5100351889- Protein purification and stability
- Microplastics and Plastic Pollution
- Analytical Chemistry and Chromatography
- biodegradable polymer synthesis and properties
- Monoclonal and Polyclonal Antibodies Research
- Platelet Disorders and Treatments
- Microbial bioremediation and biosurfactants
- Nanoparticle-Based Drug Delivery
- Metamaterials and Metasurfaces Applications
- Electrospun Nanofibers in Biomedical Applications
- Cell Adhesion Molecules Research
- Chromatography in Natural Products
- Chemical Synthesis and Analysis
- Advanced Antenna and Metasurface Technologies
- RNA Interference and Gene Delivery
- Pharmaceutical and Antibiotic Environmental Impacts
- Calcium Carbonate Crystallization and Inhibition
- Mass Spectrometry Techniques and Applications
- Protease and Inhibitor Mechanisms
- Advanced Cellulose Research Studies
- Bacteriophages and microbial interactions
- Graphene and Nanomaterials Applications
- Bacterial biofilms and quorum sensing
- Dyeing and Modifying Textile Fibers
- Blood properties and coagulation
Tianjin University
2014-2024
Shandong University of Science and Technology
2022-2024
Changchun University of Technology
2023-2024
Jiangnan University
2024
University of Waterloo
2024
Fujian Normal University
2023
Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai)
2023
Nanning Normal University
2023
Qingdao University
2023
State Key Laboratory of Pollution Control and Resource Reuse
2018-2023
Reinforcement mechanism introduced by the fully bio-based HWPU sizing agent.
ABSTRACT Rhamnolipids have multiple potential applications as “green” surfactants for industry, remediation, and medicine. As a result, they been intensively investigated to add our understanding of their biosynthesis improve yields. Several studies noted that the addition fatty acid cosubstrate increases rhamnolipid yields, but metabolic explanation has not offered, partly because date used sugar or derivatives carbon source. The objective this study was investigate role cosubstrates in...
Abstract Inhibition of amyloid β-protein (Aβ) aggregation is considered as a promising strategy for the prevention and treatment Alzheimer’s disease. Epigallocatechin-3-gallate (EGCG) curcumin have been recognized effective inhibitors Aβ aggregation. Herein, we proposed dual-inhibitor modification hyaluronic acid (HA) to explore synergistic effect two inhibitors. EGCG-modified HA (EHA) formed dispersed hydrogel structures, while EGCG-curcumin bi-modified (CEHA) self-assembled into nanogels...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSorption hysteresis as a probe of pore structureHailing Liu, Lin Zhang, and Nigel A. SeatonCite this: Langmuir 1993, 9, 10, 2576–2582Publication Date (Print):October 1, 1993Publication History Published online1 May 2002Published inissue 1 October 1993https://pubs.acs.org/doi/10.1021/la00034a016https://doi.org/10.1021/la00034a016research-articleACS PublicationsRequest reuse permissionsArticle Views314Altmetric-Citations56LEARN ABOUT THESE...
Virus-like particle (VLP) of murine polyomavirus (MPV) is a T = 7d icosahedral capsid that self-assembles from 72 capsomeres (Caps), each which pentamer major coat protein VP1. VLP has great potential in vaccinology, gene therapy, drug delivery, and materials science. However, its application hindered by high cost downstream processes, leading to an urgent demand highly efficient affinity ligand for the separation purification Cap chromatography. Herein biomimetic design strategy peptide...
PETase exhibits a high degradation activity for polyethylene terephthalate (PET) plastic under moderate temperatures. However, the effect of non-active site residues in second shell on catalytic performance remains unclear. Herein, we proposed crystal structure- and sequence-based strategy to identify key residue. D186 was found be capable modulating enzyme stability. The most active PETaseD186N improved both thermostability with an increase Tm by 8.89 °C. PET product concentrations were...
Hydrophobic charge induction chromatography (HCIC) is an adsorption combining hydrophobic interaction in with electrostatic repulsion elution. The method has been successfully applied the separation and purification of antibodies other proteins. However, little understood about protein conformational transition dynamic process within adsorbent pores. In present study, a pore model established to represent realistic porous composed matrix immobilized HCIC ligands. Protein adsorption,...
Platelet adhesion on a collagen surface through integrin α2β1 has been proven to be significant for the formation of arterial thrombus. However, molecular determinants mediating integrin-collagen complex remain unclear. In present study, dynamics binding and interactions were investigated using (MD) simulations mechanics-Poisson-Boltzmann area (MM-PBSA) analysis. Hydrophobic interaction is identified as major driving force complex. On basis MD simulation MM-PBSA results, an affinity model...
Photothermal therapy (PTT), which involves an increase in temperature triggered only by light signals at tumor sites to remove cancer cells, has been considered attractive strategy therapy. Nevertheless, the vivo applications of photosensitizer-based PTT are limited due poor biocompatibility photothermal agents. Employing red blood cell (RBC) membranes encapsulate agents can solve this issue, but extra surface coating will suppress heat dissipation, is unfavorable for subsequent treatment....
Crystal morphology has a significant effect on the properties and applications of energetic materials (EMs). Here, we have combined single-crystal X-ray diffraction (SCXRD) rotation imaging techniques to study crystal habit high explosive octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX) in different solvents. The Miller index area exposed facets been determined for HMX crystals grown acetone dimethyl sulfoxide (DMSO). For acetone, importance order (011) > (110) (020) (101̅), while...
Polyethylene terephthalate (PET) is one of the most prevalent transparent thermoplastics. It commonly utilized due to its low cost and high durability. With massive accumulation waste PET, however, serious environmental pollution has become a global problem. Compared traditional chemical degradation, biodegradation PET catalyzed by hydrolase (PETase) more environmentally friendly energy-efficient. BbPETaseCD from Burkholderiales bacterium PETase that shows favorable properties for...
Abstract Poor bone growth remains a challenge for degradable implants. Montmorillonite and strontium were selected as the carrier promoting elements to prepare strontium-doped montmorillonite coating on Mg–Ca alloy. The surface morphology composition characterized by SEM, EDS, XPS, FT-IR XRD. hydrogen evolution experiment electrochemical test results showed that alloy coated with Sr-MMT possessed optimal corrosion resistance performance. Furthermore, in vitro studies cell activity, ALP...
High ligand density is usually required in hydrophobic charge induction chromatography (HCIC) for high adsorption capacity. However, it not clear to what extent the alters and desorption behaviors, or if this leads protein conformational transition within adsorbent pores. In present study, molecular dynamics simulation performed examine effects of HCIC using a 46-bead β-barrel coarse-grained model pore established our earlier work. Four densities (1.474, 1.769, 2.212, 2.949 μmol/m2) are...
Ebola virus (EBOV) belongs to the Filoviridae family, which can cause severe hemorrhagic fever in humans and nonprimates. The neutralization of EBOV by monoclonal antibody (mAb) ADI-15946 was reported recently. In present study, molecular interactions between receptor GPcl were studied dynamics (MD) simulation mechanics–Poisson–Boltzmann surface area (MM–PBSA) analysis. Hydrophobic interaction identified as main driving force for binding on EBOV. Moreover, contribution each amino acid...