A5012719099- melanin and skin pigmentation
- Skin Protection and Aging
- Skin and Cellular Biology Research
- Contact Dermatitis and Allergies
- Dermatology and Skin Diseases
- Autoimmune Bullous Skin Diseases
- RNA regulation and disease
- Atherosclerosis and Cardiovascular Diseases
- Hair Growth and Disorders
- Facial Nerve Paralysis Treatment and Research
- Hidradenitis Suppurativa and Treatments
- Psoriasis: Treatment and Pathogenesis
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Healthcare and Venom Research
- T-cell and B-cell Immunology
- Urticaria and Related Conditions
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Cell Adhesion Molecules Research
- Dermatological and Skeletal Disorders
- Autoimmune and Inflammatory Disorders
- Facial Rejuvenation and Surgery Techniques
- Botulinum Toxin and Related Neurological Disorders
- Ophthalmology and Eye Disorders
- Air Quality and Health Impacts
- Amyloidosis: Diagnosis, Treatment, Outcomes
Yonsei University
2022-2025
Severance Hospital
2022-2024
Gangnam Severance Hospital
2022-2023
Korea University
2015
Refractory pruritus is the most distressing, disease-related symptom in patients with dystrophic epidermolysis bullosa (DEB), inducing an itch-scratch-blister cycle. Chronic inflammation a hallmark of DEB, thus upregulation inflammatory cytokines and Janus kinase (JAK) signaling may play role DEB-related pruritus. We retrospectively reviewed medical records DEB refractory who were treated either baricitinib, JAK1/2 inhibitor, or upadacitinib, selective JAK1 inhibitor. Patients received...
Purpose: Understanding the muscle actions and resultant skin movement can enable more safe effective botulinum toxin injection for treatment of forehead wrinkles.We aimed to investigate displacement patterns adjacent due frontalis contraction using three-dimensional vector analysis.Materials Methods: Thirty healthy individuals were enrolled.Photographs face taken at rest during maximal muscle.Each expression image was aligned its respective static compute differences in position.Results:...
Patients with refractory bullous pemphigoid (BP) achieve remission after rituximab treatment but require high-dose systemic corticosteroids until the remission. The aim of this retrospective study was to examine clinical efficacy omalizumab as an adjuvant in patients BP. BP receiving either monotherapy or plus were considered for study. total dose received 60 days administration rituximab, mortality and relapse rates, median time also investigated. Of 49 included study, 25 17 combination...
Primary localized cutaneous nodular amyloidosis (PLCNA) is the rarest form of amyloidosis, characterized by deposits light chain amyloids in dermis and subcutaneous tissue, without apparent systemic involvement.One or several nodules are preferably located on extremities, trunk, face.The most useful stain for detecting amyloid fibrils Congo red, which, when combined with polarized light, makes proteins appear apple-green under a microscope.Immunohistochemical staining can help identify exact...
Air pollution, a global health concern, has been associated with adverse effects on human health. In particular, particulate matter (PM), which is major contributor to air impacts various organ systems including the skins. fact, PM suggested as culprit for accelerating skin aging and pigmentation. this study, using single-cell RNA sequencing, IL-24 was found be highly upregulated among differentially expressed genes commonly altered in keratinocytes fibroblasts of ex vivo skins exposed PM....
Pyoderma gangrenosum (PG) is a rare, non-infectious, neutrophilic dermatosis characterized by painful ulcers with indistinct borders and peripheral erythema. The diagnosis of PG requires the exclusion other causes similar appearing skin manifestations, including vasculitis infections. pathogenesis not clear; however, dysregulation immune system has been suggested in previous studies. More than half patients have underlying diseases; most common being inflammatory bowel disease (IBD)....
House dust mite (HDM) is the most common allergen exacerbating atopic dermatitis (AD), and allergen-specific immunotherapy (AIT) using HDM exhibited significant improvements in previous studies. Alopecia can occur as a complication of AD. totalis (AT), severe form alopecia areata (AA), does not respond well to treatment chance full recovery less than 10%. For extensive hair loss, topical such diphenylcyclopropenone (DPCP) used first-line treatment. However, since DPCP kind contact allergen,...