A5100420166- melanin and skin pigmentation
- Skin Protection and Aging
- Autophagy in Disease and Therapy
- NF-κB Signaling Pathways
- Circadian rhythm and melatonin
- Mast cells and histamine
- Natural product bioactivities and synthesis
- Liver Disease Diagnosis and Treatment
- Pharmacological Effects of Natural Compounds
- Advancements in Battery Materials
- Dermatologic Treatments and Research
- Phytochemicals and Antioxidant Activities
- Acne and Rosacea Treatments and Effects
- Adipokines, Inflammation, and Metabolic Diseases
- Diverse Topics in Contemporary Research
- Cancer Cells and Metastasis
- Wnt/β-catenin signaling in development and cancer
- Connexins and lens biology
- Action Observation and Synchronization
- Sirtuins and Resveratrol in Medicine
- Olfactory and Sensory Function Studies
- Advanced Battery Technologies Research
- Gestational Trophoblastic Disease Studies
- Adenosine and Purinergic Signaling
- Inflammatory mediators and NSAID effects
Yonsei University
2016-2025
Severance Hospital
1990-2024
Pusan National University
2002-2023
Sungkyunkwan University
2020-2023
Samsung (South Korea)
2023
Korea University
2002-2022
Korea University Medical Center
2022
Bucheon St. Mary's Hospital
2021
Catholic University of Korea
2021
Chosun University
2009-2020
Homogeneously dispersed Sn nanoparticles approximately ⩽10 nm in a polymerized C60 (PC60) matrix, employed as the anode of Li-ion battery, are prepared using plasma-assisted thermal evaporation coupled by chemical vapor deposition. The self-relaxant superelastic characteristics PC60 possess ability to absorb stress-strain generated and can thus alleviate problem their extreme volume changes. Meanwhile, well-dispersed dot-like nanoparticles, which surrounded thin SnO2 layer, have suitable...
Abstract Autophagy regulates cellular turnover by disassembling unnecessary or dysfunctional constituents. Recent studies demonstrated that autophagy and its regulators play a wide variety of roles in melanocyte biology. Activation is known to induce melanogenesis regulate melanosome biogenesis melanocytes. Also, induction was reported physiologic skin color via degradation, although the downstream effectors are not yet clarified. To determine role as degradation machinery, we administered...
Abstract Accumulation of advanced glycation end products (AGEs) is linked with development or aggravation many degenerative processes disorders, including aging and atherosclerosis. AGEs production in skin cells known to promote stiffness loss elasticity through their buildup connective tissue. However, the impact has yet be fully explored melanocytes. In this study, we confirmed existence receptor for AGE (RAGE) melanocytes western blot immunofluorescence along increased melanin ex vivo...
Betaine is an important human nutrient obtained from various foods. In the present study, we assessed anti-inflammatory effect of betaine on nuclear factor-kappaB (NF-kappaB) during aging. Sprague-Dawley (SD) rats, ages 7 and 21 months, were used in this study. The older rats fed betaine. To elucidate oxidative stress-induced NF-kappaB its signaling pathway at molecular levels, YPEN-1 cells used. Results showed that suppressed related gene expressions cyclooxygenase-2 (COX-2), inducible...
The reported health benefits of Korean red ginseng (KRG) include antioxidant, antitumor, antimutagenic, and immunomodulatory activities; however, the effects on oxidative stress have not yet been evaluated. Therefore, we assessed effect KRG antioxidant enzymes markers in humans.We conducted a randomized, double-blind, placebo-controlled study with three groups, including placebo, low-dose (3 g/day), high-dose (6 which were randomly assigned to healthy subjects aged 20-65 years. Lymphocyte...
In the present study, we have investigated cellular mechanisms of androgen-induced antral follicular growth arrest and possible involvement chemerin its receptor chemokine-like 1 (CMKLR1) in this process, using a chronically androgenized rat model. We hypothesize that hyperandrogenism induces follicle via action ovarian structural changes, resulting from granulosa cell oocyte apoptosis theca survival. Dihydrotestosterone (DHT) treatment resulted increased expression CMKLR1 follicles, absence...
Copper (Cu) thin films have been widely used as electrodes and interconnection wires in integrated electronic circuits more recently substrates for the synthesis of graphene. However, ultra-high vacuum processes required high-quality Cu film fabrication, such molecular beam epitaxy (MBE), restricts mass production with low cost. In this work, we demonstrated using a single-crystal target radio-frequency (RF) sputtering technique; resulting quality was comparable to that produced MBE, even...
Peroxynitrite (ONOO(-)), formed from the reaction of superoxide ((*)O(2)(-)) and nitric oxide ((*)NO), induces cellular tissue injury, resulting in several human diseases such as stroke, Alzheimer's disease, atherosclerosis. Due to lack endogenous enzymes responsible for ONOO(-) scavenging activity, finding a specific scavenger is considerable importance. In this study we examined effects zingerone ginger against ONOO(-), intracellular RS (reactive species), ONOO(-). The data show that can...
[Purpose] Many assumptions have been made about taping and several studies considered tape application methods; however, the true effect of on muscle strength remains unclear. Most previous compared techniques using Kinesio (KT), but that non-elastic (NT) are limited. Moreover, no applied KT NT in same way to assess grip normal subjects. The purpose this study was evaluate immediate two tapes with different elastic properties maximal healthy adults. [Subjects Methods] Twenty adults were...