A5018145782- Aquaculture disease management and microbiota
- Invertebrate Immune Response Mechanisms
- Gut microbiota and health
- Aquaculture Nutrition and Growth
- Immune Cell Function and Interaction
- Sperm and Testicular Function
- Physiological and biochemical adaptations
- RNA Research and Splicing
- Immune Response and Inflammation
- Fish Ecology and Management Studies
- Dermatology and Skin Diseases
- RNA modifications and cancer
- Technology and Security Systems
- Olfactory and Sensory Function Studies
- Biochemical Analysis and Sensing Techniques
- Microbial infections and disease research
- Antimicrobial Peptides and Activities
- Ocean Acidification Effects and Responses
- Marine animal studies overview
- Immunotherapy and Immune Responses
- MicroRNA in disease regulation
- Bacteriophages and microbial interactions
- Reproductive biology and impacts on aquatic species
- Smart Grid and Power Systems
- Cancer-related molecular mechanisms research
Huazhong Agricultural University
2019-2023
Institute of Hydrobiology
2022-2023
Chinese Academy of Sciences
2022-2023
University of Chinese Academy of Sciences
2022-2023
State Nuclear Power Technology Company (China)
2021
The skin of vertebrates is the outermost organ body and serves as first line defense against external aggressions. In contrast to mammalian skin, that teleost fish lacks keratinization has evolved operate a mucosal surface containing skin-associated lymphoid tissue (SALT). Thus far, IgT representing prevalent Ig in SALT have only been reported upon infection with parasite. However, very little known about types B cells Igs responding bacterial mucosa, well inductive or effector role such...
The buccal mucosa (BM) is a critical first line of defense in terrestrial animals. To gain further insights into the evolutionary origins and primordial roles BM teleosts here we show that rainbow trout, teleost fish, contains diffuse mucosal associated lymphoid tissue (MALT) within its cavity. Upon parasite infection, fish immunoglobulin specialized immunity (sIgT) was induced to high degree, parasite-specific sIgT responses were mainly detected mucus. Moreover, trout microbiota prevalently...
The pharyngeal organ is located at the crossroad of respiratory and digestive tracts in vertebrate, it continuously challenged by varying Ags during breathing feeding. In mammals, mucosa (PM) a critical first line defense. However, evolutionary origins ancient roles immune defense microbiota homeostasis PM are still unknown. this study, to our knowledge, we find that diffuse MALT present rainbow trout, an early vertebrate. Importantly, following parasitic infection, detect strong...
The mucosa of vertebrates is a particularly complex but dynamic environment in which the host constantly interacts with trillions commensal microorganisms and pathogens. Although internal external mucosal microbiomes immune defense mammals have been well investigated, relationship between microbes their host’s responses has not systematically understood early vertebrates. In this study, we compared composition distribution microbiota common carp ( Cyprinus carpio ), found that there were...
The digestive tract is a unique series of organs that it inhabited by range commensal microbes, while also exposed to an overwhelming load dietary antigens. It widely known mammals have evolved complex and efficient immune strategies protect the mucosa tract. However, in early vertebrates, roles mucosal defense microbial communities different segments are not well understood. Here, we constructed bath infection model with infectious hematopoietic necrosis virus (IHNV) rainbow trout...
Abstract MicroRNAs are important post-transcriptional regulators, yet the molecular crosstalk between miRNAs and their target genes during sex differentiation remains poorly understood. Medaka ( Oryzias latipes ), first fish in which determination gene was identified, serves as an ideal model for studying this process. Here, we generated gonadal RNA-seq small data from XY DMY - females, wild-type females males to explore crosstalk. A total of twenty-seven datasets, comprising 188 Gb raw...
The buccal mucosa (BM) of vertebrates is a critical mucosal barrier constantly exposed to rich and diverse pathogens from air, water, food. While mammals are known contain associated lymphoid tissue (MALT) in the cavity which induces B-cells immunoglobulins (Igs) responses against bacterial pathogens, however, very little about evolutionary roles MALT immune defense. Here we developed bath infection model that rainbow trout experimentally Flavobacterium columnare (F. columnare), well as...
The olfactory organs (OOs) of vertebrates play important roles in their extraordinary chemosensory capacity, a process during which they are continuously exposed to environmental pathogens. Nasopharynx-associated lymphoid tissue (NALT) contains B cells and immunoglobulins (Igs), function as the first defense line against antigens mammals also exist teleosts. However, immune responses teleost NALT Igs bacterial infection remain largely uncharacterized. In this study, rainbow trout were...
The crosstalk between the immune system and microbiota drives an amazingly complex mutualistic symbiosis. In mammals, upper respiratory tract acts as a gateway for pathogen invasion, dynamic interaction mucosal immunity on its surface can effectively prevent disease development. However, relationship virus-mediated responses microbes in lower vertebrates remains uncharacterized. this study, we successfully constructed infection model by intraperitoneally injecting common carp ( Cyprinus...
Alternative splicing is an important way of regulating gene functions in eukaryotes. Several key genes involved sex determination and gonadal differentiation, such as nr5a1 ddx4, have sex-biased transcripts between males females, suggesting a potential regulatory role alternative gonads. Currently, the sex-specific events not been comprehensively studied at genome-wide level zebrafish. In this study, through global analysis on three independent sets RNA-seq data from matched zebrafish testes...
Organisms are colonized by microorganism communities and play a pivotal role in host function influencing physiology development. In mammals, bacterial community may alter gonadal maturation drive sex-specific differences gene expression metabolism. However, microbiota diversity the gonads of early vertebrates has not been fully elucidated. Here, we focused on swamp eel ( Monopterus albus ), which naturally undergoes sex reversal, systematically analyzed profiles between females males using...
Global warming is increasing interest in how aquatic animals can adjust their physiological performance and cope with temperature changes. Therefore, understanding the behavioral changes molecular underpinnings fish under crucial for both individual groups survival. This could provide experimental evidence resource evaluating impact of global warming. Three genetic families common carp (Cyprinus carpio) were generated. These juveniles constructed short-term (4 days) long-term (30 to...
Abstract The skin of vertebrates is the outermost organ body and serves as first line defense against external aggressions. In contrast to mammalian skin, that teleost fish lacks keratinization has evolved operate a mucosal surface containing skin-associated lymphoid tissue (SALT). Thus far, IgT representing prevalent immunoglobulin (Ig) in SALT have only been reported upon infection with parasite. However, very little known about types B cells Igs responding bacterial mucosa, well inductive...
Abstract Cell fate determination during early embryonic development is a complex process modulated by gene expression. The intricate interplay of transcriptional and post-transcriptional regulation integral to the developmental trajectory embryogenesis, yet how RNA processing may contribute programming largely elusive. Leveraging recent technological advances in single-molecule nanopore sequencing, we developed single-cell long-read transcriptome sequencing technology, allowing clear view...
The immunoglobulin (Ig) is a crucial component of adaptive immune system in vertebrates including teleost fish. Here complete cDNA sequence IgD heavy chain gene from common carp (Cyprinus carpio) was cloned and analyzed. full-length contained an open reading frame (ORF) 2460 bp encoding 813 amino acids. According to acids sequence, multiple alignment phylogenetic analysis showed that Igs are closely related those Cyprinidae Transcriptional expression as well IgM, IgZ1 IgZ2 similar patterns...
Affected by the inherent ideas like "Focus on Function Realization, Despise Security Protection", there are lots of hidden threats in industrial control system wind farms (ICS-WF), such as unreasonable IP configuration, failure virus detection and killing, which prone to illegal invasion attack from cyberspace. Those unexpected unauthorized accesses quite harmful for stable operation regional power grid. Therefore, investigating current security situation needs ICS-WF, analyzing...
Because of the lacking professional and systematic security planning layout relevant technical post setting, overwhelming wind farms are in a state "under protection" "over problems. Based on lots research practice, this paper analyzes overall functional architecture communication characteristics farm power monitoring system, clarifies protection needs, anatomizes mechanisms key points various techniques, then puts forward feasible strategies suggestions.
Global warming due to human activities and natural factors has aggravated over the years. Climate drives air water temperatures, affecting both terrestrial aquatic animals. However, little is known about effects of on fish performance, especially juvenile fish. The common carp (Cyrinus carpio), a typical distributed worldwide, can tolerate wide range climate temperatures. This study aimed investigate global behavioral responses underlying mechanisms in C. carpio, constructing model...
The swamp eel (Monopterus albus) is a commonly cultured freshwater fish. Selection and cultivation of fecund broodstock crucial for efficient artificial reproduction in this species. However, there are currently no guidelines selecting high-quality males M. albus. This study quantitatively investigated the sperm motility male eels during breeding season by using computer-assisted analysis system. Variability proportion number motile was observed between individual males. testes were grouped...