- Obesity, Physical Activity, Diet
- Diet and metabolism studies
- Nutritional Studies and Diet
- Eating Disorders and Behaviors
- Dietary Effects on Health
- Nutrition and Health in Aging
- Child Nutrition and Water Access
- Obesity and Health Practices
- Birth, Development, and Health
- Consumer Attitudes and Food Labeling
- Physical Activity and Health
- Regulation of Appetite and Obesity
- Adipose Tissue and Metabolism
- Body Composition Measurement Techniques
- Genetics, Aging, and Longevity in Model Organisms
- Child Nutrition and Feeding Issues
- Muscle metabolism and nutrition
- Nutrition, Genetics, and Disease
- Health and Lifestyle Studies
- Food composition and properties
- Infant Nutrition and Health
- Diet, Metabolism, and Disease
- Childhood Cancer Survivors' Quality of Life
- Mobile Health and mHealth Applications
- Schizophrenia research and treatment
Tufts University
2016-2025
Dartmouth College
2023-2025
University of North Carolina at Greensboro
2024
University College London
2015-2024
University College Hospital
2024
Jean Mayer Human Nutrition Research Center on Aging
2014-2023
Davidson College
2022
United States Department of Agriculture
1993-2021
Florey Institute of Neuroscience and Mental Health
2020
The University of Melbourne
2000-2020
Although disuse of skeletal muscle and undernutrition are often cited as potentially reversible causes frailty in elderly people, the efficacy interventions targeted specifically at these deficits has not been carefully studied.
Objective. The prevalence of obesity has increased dramatically in recent years. However, the role dietary composition body weight regulation remains unclear. purpose this work was to investigate acute effects glycemic index (GI) on energy metabolism and voluntary food intake obese subjects. Methods. Twelve teenage boys were evaluated three separate occasions using a crossover study protocol. During each evaluation, subjects consumed identical test meals at breakfast lunch that had low,...
Objective. To assess prospectively the influence of peers, parents, and media on development weight concerns frequent dieting. Design. Prospective cohort study. Setting. Questionnaires mailed annually to participants throughout United States. Participants. One-year follow-up 6770 girls 5287 boys who completed questionnaires in 1996 1997 were between 9 14 years age 1996. Main Outcome Measure. Onset high levels concern with dieting frequently control weight. Results. During 1 year follow-up,...
Caloric restriction (CR), energy intake reduced below ad libitum (AL) intake, increases life span in many species. The implications for humans can be clarified by randomized controlled trials of CR.To determine CR's feasibility, safety, and effects on predictors longevity, disease risk factors, quality nonobese aged 21-51 years, 218 persons were to a 2-year intervention designed achieve 25% CR or AL diet. Outcomes change from baseline resting metabolic rate adjusted weight ("RMR residual")...
Total daily energy expenditure ("total expenditure") reflects needs and is a critical variable in human health physiology, but its trajectory over the life course poorly studied. We analyzed large, diverse database of total measured by doubly labeled water method for males females aged 8 days to 95 years. increased with fat-free mass power-law manner, four distinct stages. Fat-free mass-adjusted accelerates rapidly neonates ~50% above adult values at ~1 year; declines slowly levels ~20...
Calorie restriction (CR) increases longevity in many species and reduces risk factors for chronic diseases. In humans, CR may improve health span, yet concerns remain about potential negative effects of CR.To test the effect on mood, quality life (QOL), sleep, sexual function healthy nonobese adults.A multisite randomized clinical trial (Comprehensive Assessment Long-term Effects Reducing Intake Energy Phase 2 [CALERIE 2]) was conducted at 3 academic research institutions. Adult men women (N...
Aging | doi:10.18632/aging.100994. Simin N. Meydani, Sai K. Das, Carl F. Pieper, Michael R. Lewis, Sam Klein, Vishwa D. Dixit, Alok Gupta, Dennis T. Villareal, Manjushri Bhapkar, Megan Huang, Paul J. Fuss, Susan B. Roberts, John O. Holloszy, Luigi Fontana
Abstract Nutritional epidemiology aims to link dietary exposures chronic disease, but the instruments for evaluating intake are inaccurate. One way identify unreliable data and sources of errors is compare estimated intakes with total energy expenditure (TEE). In this study, we used International Atomic Energy Agency Doubly Labeled Water Database derive a predictive equation TEE using 6,497 measures in individuals aged 4 96 years. The resultant regression predicts expected from easily...
To examine the association between frequency of consuming restaurant food and body fatness in adults.Usual free-living dietary intake from seven different types (fried chicken, burger, pizza, Chinese, Mexican, fried fish, "other") were assessed by questionnaire 73 healthy men women [ages 19 to 80, mass index (BMI) 18 33]. In addition, (percent weight) was determined hydrostatic weighing, physical activity other lifestyle parameters questionnaire. The relationship after controlling for age,...
Abstract Objective : We present an updated method for identifying physiologically implausible dietary reports by comparing reported energy intake (rEI) with predicted requirements (pER), and we examine the impact of excluding these reports. Research Methods Procedures Adult data from Continuing Survey Food Intakes Individuals 1994 to 1996 were used. pER was calculated reference equations. Within‐subject variations errors in rEI [coefficient variation (CV) ∼ 23%] over 2 days (d), (CV 11%),...
Objective: The causes of adult weight gain leading to obesity are uncertain. We examined the association and with subscales eating behavior characteristics in older women. Methods Procedures: Current height weight, (disinhibition subscales—habitual, situational, emotional; restraint subscales—flexible rigid; hunger subscales—internal external) as assessed using Eating Inventory (EI), self‐reported body at six prior age intervals were reported by 535 women aged 55–65 years. Multiple...
Abstract Objective : We examined relationships of eating patterns and reported energy intake (rEI) with BMI percentile in U.S. children. Research Methods Procedures Two 24‐hour dietary recalls from the Continuing Surveys Food Intakes by Individuals 1994 to 1996 1998 (1005 boys, 990 girls) were averaged, children categorized into three age groups: 3 5 years ( n = 1077), 6 11 537), 12 19 381). Physiologically implausible reports due reporting bias or abnormal (rEI outside ±18% 23% predicted...