A5089787757- Acute Kidney Injury Research
- Sepsis Diagnosis and Treatment
- Cardiac Arrest and Resuscitation
- COVID-19 Clinical Research Studies
- Venous Thromboembolism Diagnosis and Management
- Muscle and Compartmental Disorders
- Hemodynamic Monitoring and Therapy
- Renal function and acid-base balance
- Dialysis and Renal Disease Management
- COVID-19 and healthcare impacts
- Cardiac, Anesthesia and Surgical Outcomes
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Traumatic Brain Injury and Neurovascular Disturbances
- Infective Endocarditis Diagnosis and Management
- Electrolyte and hormonal disorders
- Pneumocystis jirovecii pneumonia detection and treatment
- Antifungal resistance and susceptibility
Amsterdam University Medical Centers
2004-2021
University of Amsterdam
2008-2020
Institute of Infection and Immunity
2008-2013
Amsterdam UMC Location University of Amsterdam
2008
Although acute renal failure (ARF) is believed to be common in the setting of critical illness and associated with a high risk death, little known about its epidemiology outcome or how these vary different regions world.To determine period prevalence ARF intensive care unit (ICU) patients multiple countries; characterize differences etiology, severity, clinical practice; impact on patient outcomes.Prospective observational study ICU who either were treated replacement therapy (RRT) fulfilled...
Coronavirus disease 2019 (COVID-19) can lead to systemic coagulation activation and thrombotic complications.To investigate the incidence of objectively confirmed venous thromboembolism (VTE) in hospitalized patients with COVID-19.Single-center cohort study 198 COVID-19.Seventy-five (38%) were admitted intensive care unit (ICU). At time data collection, 16 (8%) still 19% had died. During a median follow-up 7 days (IQR, 3-13), 39 (20%) diagnosed VTE whom 25 (13%) symptomatic VTE, despite...
Objective: According to recent research, diuretics may increase mortality in acute renal failure patients. The administration of such patients has been discouraged. Our objective was determine the impact on rate critically ill with failure. Design: Prospective, multiple-center, multinational epidemiologic study. Setting: Intensive care units from 54 centers and 23 countries. Patients: Patients were 1,743 consecutive who either treated replacement therapy or fulfilled predefined criteria for...
Objectives: To describe current practice for the discontinuation of continuous renal replacement therapy in a multinational setting and to identify variables associated with successful discontinuation. The approach discontinue may affect patient outcomes. However, there is lack information on how under what conditions discontinued. Design: Post hoc analysis prospective observational study. Setting: Fifty-four intensive care units 23 countries. Patients: Five hundred twenty-nine patients...
Background. The RIFLE classification scheme for acute kidney injury (AKI) is based on relative changes in serum creatinine (SCr) and urine output. SCr criteria, therefore, require a pre-morbid baseline value. When unknown, current recommendations are to estimate by the MDRD equation. However, approach assumes glomerular filtration rate of ∼75 mL/min/1.73 m 2 . This method has not been validated. Methods. Data from Beginning Ending Supportive Therapy Kidney (BEST Kidney) study, prospective...
Coronavirus disease 2019 (COVID-19) can lead to systemic coagulation activation and thrombotic complications. We investigated the incidence of objectively confirmed venous thromboembolism (VTE) in 198 hospitalized patients with COVID-19 a single-center cohort study. Seventy-four (37%) were admitted intensive care unit (ICU). At time data collection, 58 (29%) still 14% had died. During median follow-up 5 days (IQR, 3-9), 33 (17%) diagnosed VTE whom 22 (11%) symptomatic VTE, despite routine...
The prescription and delivery of renal replacement therapy for acute kidney injury is subject to a wide variation conditioned by multiplicity factors. A variety modalities are now available treat injury; however, there no standards the dosage, choice modality, intensity duration these therapies. Although several observational interventional studies have addressed topics, consensus recommendations in this field.The literature on topic draft research area were developed using modified Delphi...
Objectives: To evaluate the yield of mini-bronchoalveolar lavage compared with that directed bronchoalveolar in critically ill patients suspected coronavirus disease 2019–associated pulmonary aspergillosis. Design: A retrospective cohort study. Setting: The ICU Amsterdam University Medical Centers. Patients: Patients confirmed 2019 screened for INTERVENTIONS: Mini-bronchoalveolar and/or lavage. Measurements and Main Results: In total, 76 were included, 20 whom underwent lavage, 40 16 both...