A5059090868- Diabetes, Cardiovascular Risks, and Lipoproteins
- COVID-19 epidemiological studies
- Nutritional Studies and Diet
- Health and Well-being Studies
- Colorectal Cancer Screening and Detection
- Health Promotion and Cardiovascular Prevention
- COVID-19 Pandemic Impacts
- Moyamoya disease diagnosis and treatment
- Chronic Disease Management Strategies
- Sperm and Testicular Function
- Ovarian function and disorders
- Gastric Cancer Management and Outcomes
- Cardiovascular Health and Risk Factors
- Blood Pressure and Hypertension Studies
- Injury Epidemiology and Prevention
- Health disparities and outcomes
- Genetic Associations and Epidemiology
- Iron Metabolism and Disorders
- Lipoproteins and Cardiovascular Health
- Acute Ischemic Stroke Management
- Obesity, Physical Activity, Diet
- Cerebrovascular and genetic disorders
- Ophthalmology and Visual Health Research
- Ultrasound in Clinical Applications
- Coffee research and impacts
Research Institute for Endocrine Sciences
2021-2025
Shahid Beheshti University of Medical Sciences
2017-2025
University of Cambridge
2023-2025
Kharazmi University
2023
Tehran University of Medical Sciences
2015-2020
Birjand University of Medical Sciences
2019-2020
Leiden University Medical Center
2020
Shahid Beheshti University
2020
Qom University of Medical Science and Health Services
2020
Faculty of Public Health
2015
Fatigue is a common and disabling symptom in cerebrovascular disease has been associated with white matter damage, but the underlying mechanisms are poorly understood. Cerebral autosomal dominant arteriopathy subcortical infarcts leukoencephalopathy (CADASIL) most genetic form of stroke causes cerebral small vessel ischemia. We determined prevalence fatigue CADASIL, factors it, its relationship both depression cognitive impairment. Prospectively recruited genetically confirmed patients...
Background White matter hyperintensities (WMHs) are a major risk factor for stroke and dementia, but their pathogenesis is incompletely understood. It has been debated how much accounted by conventional cardiovascular factors (CVRFs), this implications as to effective preventative strategy targeting these will be. Methods Results We included 41 626 UK Biobank participants (47.2% men), with mean age of 55 years (SD, 7.5 years), who underwent brain magnetic resonance imaging at the first...
BACKGROUND: The importance of thromboembolism in the pathogenesis lacunar stroke (LS), resulting from cerebral small vessel disease (cSVD), is debated, and although antiplatelets are widely used secondary prevention after LS, there limited trial evidence well-subtyped patients to support this approach. We sought evaluate whether altered anticoagulation plays a causal role LS cSVD using 2-sample Mendelian randomization. METHODS: From recent genome-wide association study (n=81 190), we 119...
Leukemia accounts for 8% of total cancer cases and involves all age groups with different prevalence incidence rates in Iran the entire world causes a significant death toll heavy expenses diagnosis treatment processes. This study was done to evaluate epidemiology morphology blood during 2003-2008.This cross- sectional carried out based on re- analysis Cancer Registry Center report Health Deputy 6-year period (2003 - 2008). Statistical time trends change percentage performed joinpoint...
Studies on knowledge, attitude, and practice (KAP) can be valuable for public health to help in developing targeted educational programs assessing the effectiveness of interventional programs.This study was designed determine level current regarding cardiovascular diseases (CVDs), CVD risk factors symptoms adults attending care centers Tehran province.A cross-sectional performed using a self-administered questionnaire with score 0 - 100 aged > 20 years ten province, Iran. Descriptive...
Abstract Background Understanding the distinct patterns (trajectories) of variation in blood lipid levels before diagnosing cardiovascular disease (CVD) might carry important implications for improving prevention or treatment. Methods We investigated 14,373 participants (45.5% men) aged 45–84 from two large US prospective cohort studies with a median 23 years follow-up. First, we jointly estimated developmental trajectories indices, including low-density lipoprotein cholesterol (LDL-C),...
Abstract Background Studies on knowledge, attitude, and practice (KAP) can be valuable for public health to help develop targeted educational programs assess the effectiveness of intervention programs. The purpose this study was examine validity reliability a questionnaire regarding cardiovascular diseases (CVDs), their risk factors, symptoms among an Iranian general population. Methods This cross-sectional conducted population older than 20 years referred some Tehran’s healthcare centers....
Glycemic variability (GV) is developing as a marker of glycemic control, which can be utilized promising predictor complications. To determine whether long-term GV associated with incident eGFR decline in two cohorts Tehran Lipid and Glucose Study (TLGS) Multi-Ethnic Atherosclerosis (MESA) during median follow-up 12.2 years.Study participants included 4422 Iranian adults (including 528 patients T2D) aged ≥ 20 years from TLGS 4290 American 521 45 MESA. The Multivariate Cox proportional hazard...
Background Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common monogenic form of stroke associated early-onset dementia. Whether its clinical phenotype becoming milder better risk factor treatments other care improvements unknown. In a large longitudinal CADASIL cohort, we determined whether prognosis has changed over 23 years. Methods Patients were identified from Cambridge register UK Familial study. Change in age at time...
Abstract Background Understanding long-term patterns (trajectories) of cardiovascular diseases (CVD) risk and identifying different sub-groups with the same underlying could help facilitate targeted prevention programs. Methods A total 3699 participants Tehran Lipid Glucose Study (TLGS) (43% men, mean age = 53.2 years), free CVD at baseline in 1999–2001 attending least one re-examination cycle between second (2002–2005) fourth cycles (2009–2011) were included. We examined trajectories risk,...