- Global Cancer Incidence and Screening
- Breast Lesions and Carcinomas
- Breast Cancer Treatment Studies
- Global Health and Surgery
- Global Health Workforce Issues
- Cardiac, Anesthesia and Surgical Outcomes
- Genetic factors in colorectal cancer
- Urinary Bladder and Prostate Research
- Colorectal Cancer Screening and Detection
- Enhanced Recovery After Surgery
- Gastrointestinal disorders and treatments
- Delphi Technique in Research
- Cancer Risks and Factors
- Cancer and Skin Lesions
- Cervical Cancer and HPV Research
- Urinary Tract Infections Management
- Eosinophilic Esophagitis
- Sarcoma Diagnosis and Treatment
- Cancer Treatment and Pharmacology
- Inflammatory Bowel Disease
- Breast Implant and Reconstruction
- AI in cancer detection
- BRCA gene mutations in cancer
- Diagnosis and treatment of tuberculosis
- Hernia repair and management
University of Cambridge
2025
Nnamdi Azikiwe University
1999-2023
Nnamdi Azikiwe University Teaching Hospital
2005-2023
Fatigue is a common and disabling symptom in cerebrovascular disease has been associated with white matter damage, but the underlying mechanisms are poorly understood. Cerebral autosomal dominant arteriopathy subcortical infarcts leukoencephalopathy (CADASIL) most genetic form of stroke causes cerebral small vessel ischemia. We determined prevalence fatigue CADASIL, factors it, its relationship both depression cognitive impairment. Prospectively recruited genetically confirmed patients...
This study reports on the acceptance and adherence behaviors of patients presenting with a clinical suspicion breast cancer at clinic in Nigeria during 5-year period (2004-2008). Of 275 patients, 28.7% (79 patients) refused biopsy needed for definitive diagnosis. those who agreed to biopsy, 10.2% (28 did not return follow-up visit. Mastectomy was offered 140 47.9% (67 surgery. 53 diagnosed locally advanced lesions neo-adjuvant chemotherapy, 28.3% (15 completed recommended therapy. 44...
Recent evidence suggests that strengthening surgical care within existing health systems will strengthen the overall health-care system. However, Nigeria's national strategic development plan 2018-2022 placed little emphasis on care. To address gap, we worked with professional societies and other partners to develop surgical, obstetric, anaesthesia nursing 2019-2023. The aim was foster actions prioritize for achievement of universal coverage. In addition creating a costed strategy care,...
Abstract This study evaluated the potential risk factors for breast cancer in Nigerian women using a case–control design of 250 with and their age‐matched female controls. Both cases controls were recruited from 4 University Teaching Hospitals Midwestern Southeastern Nigeria. Data on clinical epidemiological characteristics collected interviewer‐administered structured questionnaires. The mean age 46.1 47.1 years, respectively. Fifty‐seven percent premenopausal while 43% postmenopausal....
Leptin, a 16 kDa polypeptide hormone, implicated in various physiological processes, exerts its action through the leptin receptor, member of class I cytokine receptor family. Both and have recently been processes leading to breast cancer initiation progression animal models humans. An A G transition mutation codon 223 exon 6 gene, resulting glutamine arginine substitution (Gln223Arg), lies within first two putative leptin-binding regions may be associated with impaired signaling capacity...
Academic global surgery is a rapidly growing field that aims to improve access safe surgical care worldwide. However, no universally accepted competencies exist inform this developing field. A consensus-based approach, with input from diverse group of experts, needed identify essential will lead standardization in task force was set up using snowball sampling recruit broad content and context experts perioperative care. draft revised through the modified Delphi process two rounds anonymous...
Abstract: The recent upsurge in global obesity and the recognition of role metabolic syndrome other correlates etiology breast cancer chronic diseases has created impetus for renewed interest anthropometric measures risk. This case-control study was designed to evaluate variables susceptibility an indigenous sub-Saharan African population drawn from midwestern southeastern Nigeria, a grossly underreported epidemiologic literature. Study participants were 250 women with who receiving...
In early 2020, the spread of coronavirus disease-2019 (COVID-19) led World Health Organization to declare this disease a pandemic. Initial epidemiological data showed that patients with cancer were at high risk developing severe forms COVID-19. National scientific societies published recommendations modifying patients' breast (BC) management preserve, in theory, quality oncologic care, avoiding increased contamination. The Senology International Society (SIS) decided take an inventory...
Aims and Objectives: Breast lumps are quite common, but the principal issue is differentiating malignant from benign sub-groups. The determinants of histologic diagnosis multifactorial, ranging environmental, genetic to sex age-related factors. This study aimed document spectrum breast in our environment.Materials Methods: a descriptive prospective analysis consecutive biopsied at Federal Teaching Hospital Abakaliki, between December 2010 November 2012. data were analysed using statistical...
Therapeutic management of ductal carcinoma in situ (DCIS) is heterogeneous among countries worldwide, and some treatment indications are still controversial. To investigate DCIS different countries; identify both consensual practices controversial topics; survey opinions about the future DCIS.The Senologic International Society network members participated to an online using a questionnaire, between November 2021 February 2022.Twenty-two responses from 20 showed that organized breast cancer...
Objective: This study aimed to determine if there is association between gastric perforation and non-steroidal anti-inflammatory drugs (NSAIDs) abuse in patients presenting with perforated peptic ulcer disease (PPUD). Material Methods:The data were collected retrospectively from May 2011 2015 then prospectively until December 2017.Sixty diagnosed PPUD on exploratory laparotomy evaluated.Data analyzed using SPSS (version 21.0).P value ≤ 0.05 was considered significant.Results: A total of 60...
Peutz-Jeghers syndrome is a rare condition of muco-cutaneous pigmentation and polyposis the gut. Reports its occurrence from Black world have been infrequent. A case presented an 18 year old Nigerian girl with inner lips soles both feet, recurrent attacks abdominal pain necessitating two surgical procedures for intestinal obstruction removal, in cases, polyps. Problems complications therapeutic modalities are discussed.
There is increasing tendency to multidisciplinary care of patients with breast lesions. This study sought evaluate the initial experience diagnostic arm a new program in resource limited setting.In 2015, we commenced pilot phase an IRB-approved protocol. As part protocol's arm, ultrasound-guided core biopsy training was implemented. Eligible were clinically evaluated and underwent CNB using 16G needle under US guidance. The procedure rated by participants histopathological results compared...